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Solute Carrier Organic Anion Transporter Family, Member 1B1 Proteins (SLCO1B1)

SLCO1B1 encodes a liver-specific member of the organic anion transporter family. Additionally we are shipping SLCO1B1 Antibodies (41) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
SLCO1B1 10599 Q9Y6L6
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Top SLCO1B1 Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 59 to 64 Days
$8,623.45
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details

SLCO1B1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,

More Proteins for Solute Carrier Organic Anion Transporter Family, Member 1B1 (SLCO1B1) Interaction Partners

Human Solute Carrier Organic Anion Transporter Family, Member 1B1 (SLCO1B1) interaction partners

  1. SLCO1B1 rs113681054, SLCO1B1*5 (rs4149056), CYP3A4 (show CYP3A4 Proteins)*1G (rs2242480), and CYP3A4 (show CYP3A4 Proteins)*5 (rs776746) polymorphisms had no effect on the PK/PD of ticagrelor in healthy Chinese volunteers

  2. SLCO1B1 gene variants could affect the pharmacodynamics of rocuronium.

  3. Polymorphism of SLCO1B1 c.521 T > C could be a strong predictor of 6-MP dose reduction in maintenance chemotherapy in childhood ALL.

  4. No significant difference was observed in the lipid-lowering efficacy of statins between the wild and variant genotypes of SLCO1B1.

  5. Patients under pravastatin treatment prior to inguinal hernia repair presented with lower postoperative IL-10 (show IL10 Proteins) levels with respect to the baseline concentration, regardless of the presence or absence of SLCO1B1 *1 or SLCO1B1 *5 polymorphisms.

  6. transport of CPR (show POR Proteins) I mediated by OATP1B1 and OATP1B3 and the transport of CPR (show POR Proteins) III mediated by OATPs 1B1, 1B3 and 2B1 (show SPI1 Proteins) is time-dependent, can be saturated and inhibited

  7. The SLCO1B1 rs1104581 polymorphism, weight, and gender appear to play important roles for rifabutin efficiency in African HIV-Infected patients with tuberculosis.

  8. Results identified interethnic differences of genetic variations of the SLCO1B1, SLCO1B3, and SLCO2B1 (show SLCO2B1 Proteins) genes in Korean population compared with other ethnic groups.

  9. SLCO1B1 variants are strongly associated with an increased risk of enalapril-induced cough.

  10. TM11 of OATP1B1 may face the substrate interaction pocket.

SLCO1B1 Protein Profile

Protein Summary

This gene encodes a liver-specific member of the organic anion transporter family. The encoded protein is a transmembrane receptor that mediates the sodium-independent uptake of numerous endogenous compounds including bilirubin, 17-beta-glucuronosyl estradiol and leukotriene C4. This protein is also involved in the removal of drug compounds such as statins, bromosulfophthalein and rifampin from the blood into the hepatocytes. Polymorphisms in the gene encoding this protein are associated with impaired transporter function.

Gene names and symbols associated with SLCO1B1

  • solute carrier organic anion transporter family, member 1B1 (SLCO1B1)
  • HBLRR protein
  • LST-1 protein
  • LST1 protein
  • OATP-C protein
  • OATP1B1 protein
  • OATP2 protein
  • OATPC protein
  • SLC21A6 protein
  • SLCO1B1 protein

Protein level used designations for SLCO1B1

OATP-2 , liver-specific organic anion transporter 1 , sodium-independent organic anion-transporting polypeptide 2 , solute carrier family 21 (organic anion transporter), member 6 , solute carrier family 21 member 6 , solute carrier organic anion transporter family member 1B1 , solute carrier organic anion transporter family, member 1B1 , solute carrier organic anion transporter family member 1B1-like

GENE ID SPECIES
10599 Homo sapiens
465331 Pan troglodytes
705308 Macaca mulatta
100011628 Monodelphis domestica
100448597 Pongo abelii
100585039 Nomascus leucogenys
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