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Solute Carrier Organic Anion Transporter Family, Member 1B1 Proteins (SLCO1B1)

SLCO1B1 encodes a liver-specific member of the organic anion transporter family. Additionally we are shipping SLCO1B1 Antibodies (40) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
SLCO1B1 10599 Q9Y6L6
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Top SLCO1B1 Proteins at antibodies-online.com

Showing 2 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 Days
$5,442.50
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HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
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SLCO1B1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
, ,

More Proteins for Solute Carrier Organic Anion Transporter Family, Member 1B1 (SLCO1B1) Interaction Partners

Human Solute Carrier Organic Anion Transporter Family, Member 1B1 (SLCO1B1) interaction partners

  1. Polymorphisms of the SLCO1B1 gene ate used for predicting risk of adverse events when using statins.

  2. Critical amino acid residues in the predicted transmembrane pore influencing transport kinetics of the hepatic drug transporter OATP1B1 have been identified.

  3. Genetic polymorphisms of the UGT1A1 (show UGT1A1 Proteins) promoter, specifically the T-3279G phenobarbital-responsive enhancer module and (TA)7 dinucleotide repeat, as well as the intron and coding region variants of the OATP2, HMOX1 (show HMOX1 Proteins), and BLVRA (show BLVRA Proteins) genes, were significantly higher among the cases than the controls.

  4. SLCO1B1 genotype was not associated with the risk of statin-associated muscle symptoms.

  5. these findings demonstrate an important role for OATP1B1 in the systemic pharmacokinetics of multiple drugs used in the treatment of acute myeloid leukemia (show BCL11A Proteins)

  6. Genetic link with cholelithiasis among pediatric SCA Tunisian patients: Examples of UGT1A1 (show UGT1A1 Proteins), SLCO1A2 and SLCO1B1.

  7. SLCO1B1 rs113681054, SLCO1B1*5 (rs4149056), CYP3A4 (show CYP3A4 Proteins)*1G (rs2242480), and CYP3A4 (show CYP3A4 Proteins)*5 (rs776746) polymorphisms had no effect on the PK/PD of ticagrelor in healthy Chinese volunteers

  8. SLCO1B1 gene variants could affect the pharmacodynamics of rocuronium.

  9. Polymorphism of SLCO1B1 c.521 T > C could be a strong predictor of 6-MP dose reduction in maintenance chemotherapy in childhood ALL.

  10. No significant difference was observed in the lipid-lowering efficacy of statins between the wild and variant genotypes of SLCO1B1.

SLCO1B1 Protein Profile

Protein Summary

This gene encodes a liver-specific member of the organic anion transporter family. The encoded protein is a transmembrane receptor that mediates the sodium-independent uptake of numerous endogenous compounds including bilirubin, 17-beta-glucuronosyl estradiol and leukotriene C4. This protein is also involved in the removal of drug compounds such as statins, bromosulfophthalein and rifampin from the blood into the hepatocytes. Polymorphisms in the gene encoding this protein are associated with impaired transporter function.

Gene names and symbols associated with SLCO1B1

  • solute carrier organic anion transporter family, member 1B1 (SLCO1B1)
  • HBLRR protein
  • LST-1 protein
  • LST1 protein
  • OATP-C protein
  • OATP1B1 protein
  • OATP2 protein
  • OATPC protein
  • SLC21A6 protein
  • SLCO1B1 protein

Protein level used designations for SLCO1B1

OATP-2 , liver-specific organic anion transporter 1 , sodium-independent organic anion-transporting polypeptide 2 , solute carrier family 21 (organic anion transporter), member 6 , solute carrier family 21 member 6 , solute carrier organic anion transporter family member 1B1 , solute carrier organic anion transporter family, member 1B1 , solute carrier organic anion transporter family member 1B1-like

GENE ID SPECIES
10599 Homo sapiens
465331 Pan troglodytes
705308 Macaca mulatta
100011628 Monodelphis domestica
100448597 Pongo abelii
100585039 Nomascus leucogenys
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