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mediates the transport of sulfated, amidated bile acid, sulfolithocholyltaurine, into rat hepatocytes [RGD, Feb 2006].. Additionally we are shipping Slco1a1 Antibodies (3) and and many more products for this protein.
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Data indicate that organic anion-transporting polypeptides Oatp1a/1b-null mice had increased levels of carboxylesterase (Ces) enzymes, which caused higher conversion of irinotecan to SN-38 in plasma, potentially complicating pharmacokinetic analyses.
PDZK1 (show PDZK1 ELISA Kits) regulates intracellular trafficking of Oatp1a1.
Loss of Oatp1a1 function exacerbates cholestatic liver injury in mice and suggest that Oatp1a1 plays a unique role in liver adaptive responses to obstructive cholestasis.
Dysfunction of organic anion transporting polypeptide 1a1 alters intestinal bacteria and bile acid metabolism.
Oatp1a1 is more highly expressed in males than in females. Null mice showed inhibited hepatocyte transporter functions and an altered urinary metabolome.
Organic anion transporting polypeptide 1a/1b-knockout mice provide insights into hepatic handling of bilirubin, bile acids, and drugs.
organic anion transporting polypeptide-1 (Oatp1) were down-regulated by taurocholate and not affected by cholestyramine feeding
In conclusion, gender-divergent Oatp (show SLCO1A2 ELISA Kits) expression in liver is caused by male-pattern GH secretion pattern and androgens. In kidney, gender-divergent Oatp1a1 expression is exclusively caused by stimulation by androgens.
Report critical role of PPAR-alpha (show PPARA ELISA Kits) in perfluorooctanoic acid- and perfluorodecanoic acid-induced downregulation of Oatp1a1 uptake transporter in mouse liver.
mediates the transport of sulfated, amidated bile acid, sulfolithocholyltaurine, into rat hepatocytes
sodium-independent organic anion-transporting polypeptide 1
, solute carrier family 21 (organic anion transporter), member 1
, solute carrier family 21 member 1
, solute carrier organic anion transporter family member 1A1
, organic anion-transporting polypeptide 1
, sodium-independent organic anion transporter 1
, solute carrier family (organic anion transporter) member 1
, solute carrier family (organic anion transporter) member 3
, solute carrier family 21, member 1