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SLCO2A1 encodes a prostaglandin transporter that is a member of the 12-membrane-spanning superfamily of transporters. Additionally we are shipping SLCO2A1 Proteins (5) and many more products for this protein.
Showing 10 out of 22 products:
Human Polyclonal SLCO2A1 Primary Antibody for ELISA, WB - ABIN562902
Mandery, Bujok, Schmidt, Wex, Treiber, Malfertheiner, Rau, Amann, Brune, Fromm, Glaeser: Influence of cyclooxygenase inhibitors on the function of the prostaglandin transporter organic anion-transporting polypeptide 2A1 expressed in human gastroduodenal mucosa. in The Journal of pharmacology and experimental therapeutics 2010
Show all 3 references for ABIN562902
Because no phenotype associated differences could be found in the gene sequence nor in its jejunal transcription profile, SLCO2A1 can most likely be excluded as receptor for F4 bacteria.
overexpression of SLCO2A1 could induce and knockdown inhibit the invasion of lung cancer cells. expression levels of p-mTOR (show FRAP1 Antibodies), p-AKT (show AKT1 Antibodies) and p-S6 were up-regulated or down-regulated with the overexpression or knockdown of SLCO2A1.
cytoplasmic OATP2A1 likely facilitates prostaglandin E2 loading into suitable intracellular compartment(s) for efficient exocytotic prostaglandin E2 release from colorectal cancer cells exposed to oxidative stress
findings indicate that loss-of-function mutations in the SLCO2A1 gene encoding a prostaglandin transporter cause the hereditary enteropathy CNSU
SLCO2A1 and NOS3 (show NANOS3 Antibodies) are involved with prostaglandin reuptake/metabolism and nitric oxide production, respectively, and are consistently decreased in "non-Caucasian" fetal ductus arteriosus
Multiple drug resistance-associated protein (show ABCC1 Antibodies) 4 (MRP4 (show ABCC4 Antibodies)), prostaglandin transporter (PGT), and 15-hydroxyprostaglandin dehydrogenase (15-PGDH (show HPGD Antibodies)) as determinants of PGE2 levels in cancer.
OATP2A1 also diminished the PGE2-mediated expression of interleukin-8 (show IL8 Antibodies) mRNA (IL-8 (show IL8 Antibodies)) and hypoxia-inducible-factor 1alpha (HIF1alpha (show HIF1A Antibodies)) protein in AGS (show JAG1 Antibodies)-OATP2A1 cells.
SLCO2A1 has a role in familial digital clubbing, colon neoplasia, and NSAID resistance
a novel nonsense mutation p.E141* of the SLCO2A1 gene is associated with pachydermoperiostosis
Genetic variability in key genes in prostaglandin E2 pathway (COX-2 (show COX2 Antibodies), HPGD (show HPGD Antibodies), ABCC4 (show ABCC4 Antibodies) and SLCO2A1) and their involvement in colorectal cancer development.
Three novel mutations within the SLCO2A1 gene have been demonstrated to be associated with Chinese primary hypertrophic osteoarthropathy patients.
Slco2a1 contributes to PGE2 secretion by macrophages via exocytosis.
Pulmonary Prostaglandin E2 disposition is largely regulated by SLCO2A1, demonstrating that SLCO2A1 plays a critical role in protecting the lung from Bleomycin-induced fibrosis.
Prostaglandin transporter plays a critical role in closure of the ductus arteriosus after birth by ensuring a reduction in local and/or circulating PGE (show LIPF Antibodies)(2) concentrations.
Renal collecting duct prostaglandin transporter transcription varied with dietary salt intake.
This gene encodes a prostaglandin transporter that is a member of the 12-membrane-spanning superfamily of transporters. The encoded protein may be involved in mediating the uptake and clearance of prostaglandins in numerous tissues.
solute carrier organic anion transporter family, member 2A1
, matrin F/G 1
, prostaglandin transporter
, solute carrier family 21 (prostaglandin transporter), member 2
, solute carrier family 21 member 2
, solute carrier organic anion transporter family member 2A1