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Receptor for somatostatin with higher affinity for somatostatin-14 than -28. Additionally we are shipping SSTR1 Kits (29) and SSTR1 Proteins (5) and many more products for this protein.
Showing 10 out of 108 products:
Human Polyclonal SSTR1 Primary Antibody for IHC (p) - ABIN115393
Gu, Brown, Loose-Mitchell, Stork, Schonbrunn: Development and use of a receptor antibody to characterize the interaction between somatostatin receptor subtype 1 and G proteins. in Molecular pharmacology 1996
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Data showed that the distribution of somatostatin (show SST Antibodies) receptor (SSTR (show SSTR3 Antibodies)) subtypes among the 199 pancreatic neuroendocrine tumors (PNETs) was: SSTR2 (show SSTR2 Antibodies) (54.8%), SSTR1 (53.3%), SSTR4 (show SSTR4 Antibodies) (51.8%), SSTR5 (show SSTR5 Antibodies) (33.7%), and SSTR3 (show SSTR3 Antibodies) (28.6%).
An immunohistochemical investigation of the expression of somatostatin (show SST Antibodies) receptor subtypes
Aberrant methylation inactivates somatostatin (show SST Antibodies) and SSTR1 in head and neck squamous cell carcinoma.
The UMB-7 may prove of great value in the identification of sst1-expressing tumors during routine histopathological examinations. This may open up new routes for diagnostic and therapeutic intervention.
SSTR (show SSTR3 Antibodies)-PET showed high sensitivity for imaging bone, soft tissue and brain metastases, and particularly in combination with CT had a significant impact on clinical stage and patient management.
Activated/phosphorylated pMAPK 44/42 was detected in 82% of medulloblastomas, all subtypes, and in 62.5% of primitive neuroectodermal tumors with coexpression of SSR1 (show SSR1 Antibodies) in one third.
Somatostatin (show SST Antibodies) receptor imaging (SRI (show SRI Antibodies)) using SPECT or PET as a whole-body imaging technique has become a crucial part of the management of Neuroendocrine tumors
Tumor cells in the tissue samples of the patients diagnosed with advanced-stage hepatocellular carcinoma expressed a high proportion of SSTR1 and SSTR5 (show SSTR5 Antibodies).
Somatostatin receptor 1 is a novel methylated gene driven by EBV infection in gastric cancer cells and acts as a potential tumour suppressor.
Data demonstrate that cells transfected with SSTR1 or SSTR1/5 negatively regulates EGF (show EGF Antibodies) mediated effects attributed to the inhibition of EGFR (show EGFR Antibodies) phosphorylation.
This study showed that reduced expression of the Sstr1 which modulate antidepressant action in hippocampus.
The expression and localization of the three receptors (SSTR3 (show SSTR3 Antibodies)-SSTR5 (show SSTR5 Antibodies)) in wild-type (WT), single-knockout (SSTR1 KO) and double-knockout SSTR1/SSTR2 (show SSTR2 Antibodies) (DKO) mice, are reported.
SSTR1 was expressed in Kolliker's organ on E14 (show NPAT Antibodies), on cochlear duct hair cells & supporting cells on E17 and only on the organ of Corti at birth, increasing & peaking at P14 (show PCOLCE Antibodies) but dropping off at P21 (show D4S234E Antibodies).
SSTR1-like immunoreactivity increases in hypothalamus except in paraventricular nucleus of ApoD (show APOD Antibodies)(-/-) mice.
SST (show SST Antibodies) and SSTRs might play an important role in regulation of neurodegeneration
Data suggest an important role for the brain somatostatin receptor 1 subtype in the modulation of the gastrointestinal response to activation of brain CRF (show CRH Antibodies) pathways.
The effect of sst2 (show SSTR2 Antibodies) receptor knockout on sst1 receptor mRNA localization and binding sites throughout the brain has been determined.
The localization of somatostatin (show SST Antibodies) to retinal amacrine cells, together with the expression of somatostatin (show SST Antibodies) receptors in amacrine, bipolar and horizontal cells suggests that somatostatin (show SST Antibodies) acts at multiple levels of retinal circuitry.
Brain somatostatin (show SST Antibodies) receptors 1,2,4 and 5 are up-regulated in somatostatin (show SST Antibodies)-deficient mice, and SSTR3 (show SSTR3 Antibodies) is down-regulated.
sst1 receptor loss causes a significant increase in retinal levels of somatostatin-14 (show SST Antibodies) (SRIF (show SST Antibodies)) whereas it does not affect SRIF (show SST Antibodies) messenger RNA, indicating that sst1 receptors play a role in limiting retinal SRIF (show SST Antibodies) at the post-transcriptional level.
Receptor for somatostatin with higher affinity for somatostatin-14 than -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and Na(+)/H(+) exchanger via pertussis toxin insensitive G proteins.
somatostatin receptor type 1
, somatostatin receptor 1
, Somatostatin receptor subtype 1