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Intercellular signal essential for a variety of patterning events during development. Additionally we are shipping and many more products for this protein.
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Zebrafish (Danio rerio) Polyclonal SHHA Primary Antibody for WB - ABIN1882186
Ekker, Ungar, Greenstein, von Kessler, Porter, Moon, Beachy: Patterning activities of vertebrate hedgehog proteins in the developing eye and brain. in Current biology : CB 1995
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Opposing Shh (show SHH Antibodies) and Fgf signals initiate nasotemporal patterning of the zebrafish retina.
Hedgehog (show SHH Antibodies) signaling has a role in dental papilla formation and tooth size during zebrafish odontogenesis
Data indicate that the transgenic lines report Hedgehog (show SHH Antibodies) pathway state in individual cells and with high sensitivity.
We further demonstrate that the elevated Hedgehog (show SHH Antibodies) signaling in Sox11 (show SOX11 Antibodies)-deficient zebrafish was caused by a large increase in shha transcription; indeed, suppressing Shha expression rescued the ocular phenotypes of sox11 (show SOX11 Antibodies) morphants.
Pax6 (show PAX6 Antibodies) has an evolutionarily conserved function in establishing the temporospatial expression of Shh (show SHH Antibodies) in the mid-diencephalic organizer in vertebrates.
Sulf1 (show SULF1 Antibodies) triggers Shh (show SHH Antibodies) signaling activity to establish and, later on, modify the spatial arrangement of gene expression in ventral neural progenitors
These studies provide evidence that a signaling pathway involving agrin (show AGRN Antibodies), Fgfs and Shh (show SHH Antibodies) may be a critical target of ethanol exposure during zebrafish embryogenesis.
heterozygote mutations in fgf8 (show FGF8 Antibodies), shh (show SHH Antibodies) or oep (show TDGF1 Antibodies) lead to a reduced number of ascending dopaminergic neurons in zebrafish and may confer increased susceptibility to the Parkinson disease
Hh is able to bypass VEGF to induce arterial differentiation in ECs via the calcitonin receptor-like receptor, thus revealing a surprising complexity in the interplay between Hh and VEGF signaling during arteriovenous specification.
The Sphingosine-1-phospate-dependent anterior foregut endoderm functions primarily through Shh (show SHH Antibodies) to regulate the growth but not dorsoventral patterning of zebrafish jaw precursors.
Intercellular signal essential for a variety of patterning events during development. Signal produced by the notochord that induces somite patterning, dorso-ventral patterning of the brain and early patterning of the developing eyes. Displays floor plate-inducing activity. Binds to the patched (PTC) receptor, which functions in association with smoothened (SMO), to activate the transcription of target genes. In the absence of SHH, PTC represses the constitutive signaling activity of SMO (By similarity).
sonic hedgehog protein A