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anti-Sorbin and SH3 Domain Containing 1 (SORBS1) Antibodies

Plays a role in tyrosine phosphorylation of CBL by linking CBL to the insulin receptor. Additionally we are shipping SORBS1 Kits (4) and SORBS1 Proteins (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SORBS1 10580 Q9BX66
SORBS1 20411 Q62417
SORBS1 686098  
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Top anti-SORBS1 Antibodies at antibodies-online.com

Showing 10 out of 77 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Goat Un-conjugated IHC (p) 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Goat Un-conjugated IHC, ELISA, WB ABIN184759 (2.5µg/ml) staining of paraffin embedded human skeletal muscle. Steamed antigen retrieval with citrate buffer pH 6, AP-staining. 100 μg Log in to see 4 to 5 Days
$318.20
Details
Hamster Rabbit Un-conjugated EIA, WB Confocal immunofluorescent analysis of SORBS1 / Ponsinin Antibody  with MDA-MB231 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue). Western blot analysis of SORBS1 / Ponsinin Antibody  in CHO cell line lysates (35ug/lane). This demonstrates the SORBS1 antibody detected the SORBS1 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$401.50
Details
Human Goat Un-conjugated ELISA, WB   100 μg Log in to see 4 to 5 Days
$221.76
Details
Human Goat Un-conjugated ELISA, WB   100 μg Log in to see 4 to 5 Days
$221.76
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-Sorbs1 AntibodyTitration: 1.0 µg/mL  Positive Control: Mouse Testis 100 μL Log in to see 2 to 3 Days
$289.00
Details
Hamster Rabbit Un-conjugated IF, WB Confocal immunofluorescent analysis of SORBS1 Antibody (Center) (ABIN654646) with MDA-MB231 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Goat Un-conjugated IHC, ELISA 0.1 mg Log in to see 2 to 3 Days
$433.13
Details
Human Goat Un-conjugated IHC (p), ELISA Human Skeletal Muscle (formalin-fixed, paraffin-embedded) stained with SORBS1 antibody ABIN290372 at 5 ug/ml followed by biotinylated anti-goat IgG secondary antibody ABIN481715, alkaline phosphatase-streptavidin and chromogen. 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Goat Un-conjugated IHC (p), ELISA Human Skeletal Muscle (formalin-fixed, paraffin-embedded) stained with SORBS1 antibody ABIN297694 at 2.5 ug/ml followed by biotinylated anti-goat IgG secondary antibody ABIN481715, alkaline phosphatase-streptavidin and chromogen. 50 μg Log in to see 8 to 10 Days
$451.00
Details

SORBS1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , , ,
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Mouse (Murine) , , ,
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Rat (Rattus) , , ,
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Top referenced anti-SORBS1 Antibodies

  1. Hamster Polyclonal SORBS1 Primary Antibody for EIA, WB - ABIN954882 : Gehmlich, Hayess, Legler, Haebel, Van der Ven, Ehler, Fürst: Ponsin interacts with Nck adapter proteins: implications for a role in cytoskeletal remodelling during differentiation of skeletal muscle cells. in European journal of cell biology 2010 (PubMed)
    Show all 4 references for ABIN954882

  2. Human Polyclonal SORBS1 Primary Antibody for IHC (p) - ABIN374225 : Ribon, Printen, Hoffman, Kay, Saltiel: A novel, multifuntional c-Cbl binding protein in insulin receptor signaling in 3T3-L1 adipocytes. in Molecular and cellular biology 1998 (PubMed)

  3. Human Polyclonal SORBS1 Primary Antibody for ELISA, WB - ABIN190836 : Baumann, Ribon, Kanzaki, Thurmond, Mora, Shigematsu, Bickel, Pessin, Saltiel: CAP defines a second signalling pathway required for insulin-stimulated glucose transport. in Nature 2000 (PubMed)

  4. Human Polyclonal SORBS1 Primary Antibody for ELISA, WB - ABIN185598 : Matson, Pare, Kapiloff: A novel isoform of Cbl-associated protein that binds protein kinase A. in Biochimica et biophysica acta 2005 (PubMed)

More Antibodies against SORBS1 Interaction Partners

Human Sorbin and SH3 Domain Containing 1 (SORBS1) interaction partners

  1. data suggest that SORBS1 might be a gene involved in diabetic nephropathy.

  2. Our NMR and ITC data indicate that the SH3a and SH3b domains of CAP simultaneously bind to a long proline-rich region of vinculin (show VCL Antibodies) with different binding specificities

  3. Sequestration of the ponsin splice variant R85FL by the polyglutamine-expanded Atx7 in cell is mediated by the specific SH3C-PRR (show PVRL1 Antibodies) interaction, which is implicated in the pathogenesis of spinocerebellar ataxia (show USP14 Antibodies) 7.

  4. a novel signaling network containing FRS2 (show FRS2 Antibodies), CAP and flotillin-1 (show FLOT1 Antibodies)

  5. The novel ponsin isoform and its interaction with Nck1 (show NCK1 Antibodies)/2 provide exciting insight into the convergence of signalling pathways at the costameres, and its crucial role for skeletal muscle differentiation and re-generation.

  6. preliminary results indicate the depot-specific differential expression of sorbin and SH3 domain-containing-1(SORBS1) in relation to body mass index

  7. SORBS1 polymorphism does not play a major role in premature pubarche, hyperandrogenism, and/or polycystic ovary syndrome in children and adolescent girls.

  8. Soluble intracellular domain of teneurin-1 (show ODZ1 Antibodies) binds to the cell membrane enriched in CAP/ponsin

  9. analysis of paxillin (show PXN Antibodies) and ponsin interaction in nascent costameres of muscle cells

  10. AA genotype of SORBS1 T228A polymorphism may play a role in lacunar infarction in the Japanese population.

Mouse (Murine) Sorbin and SH3 Domain Containing 1 (SORBS1) interaction partners

  1. The study screened CrkL (show CRKL Antibodies) binding proteins using RNA interference (RNAi) and identified Sorbs1 and Sorbs2 (show Sorbs2 Antibodies) as two proteins that are enriched at AChR clusters and are required for the formation of AChR aggregation in vitro.

  2. Suggest a novel modulatory role for CAP in the heart as a key protein stabilizing antiviral type I interferon (show IFNA Antibodies) production, while protecting from excessive cytotoxic responses in CVB3 mediated endocarditis.

  3. Low- and high-dose ursolic acid can improve the glycometabolism and differentiation of 3T3-L1 adipocytes with insulin (show INS Antibodies) resistance by up-regulating the expression of CAP.

  4. a novel signaling network containing FRS2 (show FRS2 Antibodies), CAP and flotillin-1 (show FLOT1 Antibodies)

  5. The novel ponsin isoform and its interaction with Nck1 (show NCK1 Antibodies)/2 provide exciting insight into the convergence of signalling pathways at the costameres, and its crucial role for skeletal muscle differentiation and re-generation.

  6. CAP, Cbl (show CBL Antibodies) iso-forms, and CrkII (show CRK Antibodies) are not required components of insulin (show INS Antibodies) signaling to GLUT4 (show SLC2A4 Antibodies) transporters

  7. Bone marrow-specific Sorbs1 (Cap) gene deletion protects against high-fat diet-induced insulin (show INS Antibodies) resistance.

  8. These data provide a mechanism for the lipid raft localization of TrkA (show NTRK1 Antibodies) and establish the importance of the CAP adaptor protein for nerve growth factor activation of the extracellular signal-regulated kinase and neuronal differentiation.

SORBS1 Antigen Profile

Protein Summary

Plays a role in tyrosine phosphorylation of CBL by linking CBL to the insulin receptor. Required for insulin- stimulated glucose transport. Involved in formation of actin stress fibers and focal adhesions.

Gene names and symbols associated with SORBS1

  • sorbin and SH3 domain containing 1 (SORBS1) antibody
  • sorbin and SH3 domain containing 1 (Sorbs1) antibody
  • 2310065E01Rik antibody
  • 9530001P15Rik antibody
  • CAP antibody
  • FLAF2 antibody
  • mKIAA1296 antibody
  • R85FL antibody
  • Sh3d5 antibody
  • SH3P12 antibody
  • SORB1 antibody

Protein level used designations for SORBS1

Fas-ligand associated factor 2 , SH3 domain protein 5 , SH3-domain protein 5 (ponsin) , c-Cbl associated protein , c-Cbl-associated protein , ponsin , sorbin and SH3 domain-containing protein 1

GENE ID SPECIES
10580 Homo sapiens
20411 Mus musculus
686098 Rattus norvegicus
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