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anti-Sorbin and SH3 Domain Containing 2 (Sorbs2) Antibodies

Arg and c-Abl represent the mammalian members of the Abelson family of non-receptor protein-tyrosine kinases. Additionally we are shipping Sorbs2 Proteins (4) and Sorbs2 Kits (1) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
Sorbs2 8470 O94875
Sorbs2 234214  
Sorbs2 114901 O35413
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Top anti-Sorbs2 Antibodies at antibodies-online.com

Showing 10 out of 26 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated FACS, IF, IHC (p), WB Western blot analysis of ARGBP2 Antibody (N-term) (ABIN652279) in MDA-MB231 cell line lysates (35 µg/lane). ARGBP2 (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human colon carcinoma reacted with ARGBP2 Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of ARGBP2 Antibody (N-term) in MDA-MB231 cell line lysates (35ug/lane). ARGBP2 (arrow) was detected using the purified Pab. 0.4 mL Log in to see 6 to 8 Days
$401.50
Details
Human Mouse Un-conjugated IF, WB Western Blot analysis of SORBS2 expression in transfected 293T cell line by SORBS2 MaxPab polyclonal antibody.Lane 1: SORBS2 transfected lysate(121 KDa).Lane 2: Non-transfected lysate. Immunofluorescence of purified MaxPab antibody to SORBS2 on HepG2 cell. [antibody concentration 10 ug/ml] 50 μg Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded human colon carcinoma labeled with Anti SORBS2 Polyclonal Antibody, Unconjugated (ABIN1387807) at 1:200 followed by conjugation to the secondary antibody and DAB staining Formalin-fixed and paraffin embedded mouse tumor tissue labeled with Anti SORBS2 Polyclonal Antibody, Unconjugated (ABIN1387807) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$269.50
Details
Human Rabbit Alexa Fluor 647 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Biotin IHC (p), WB   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Alexa Fluor 555 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Alexa Fluor 488 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Alexa Fluor 350 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit FITC IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details

Sorbs2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Sorbs2 Antibodies

  1. Human Polyclonal Sorbs2 Primary Antibody for EIA, WB - ABIN453519 : Yuan, Kim, Kaneko, Sussman, Bokoch, Kruh, Nicosia, Testa, Cheng: ArgBP2gamma interacts with Akt and p21-activated kinase-1 and promotes cell survival. in The Journal of biological chemistry 2005 (PubMed)
    Show all 3 references for ABIN453519

  2. Human Polyclonal Sorbs2 Primary Antibody for FACS, IF - ABIN652279 : Olsen, Blagoev, Gnad, Macek, Kumar, Mortensen, Mann: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. in Cell 2006 (PubMed)
    Show all 3 references for ABIN652279

  3. Human Polyclonal Sorbs2 Primary Antibody for IF, WB - ABIN521930 : Lamberti, Sanges, Chambery, Migliaccio, Rosso, Di Maro, Papale, Marra, Parente, Caraglia, Abbruzzese, Arcari: Analysis of interaction partners for eukaryotic translation elongation factor 1A M-domain by functional proteomics. in Biochimie 2011 (PubMed)

More Antibodies against Sorbs2 Interaction Partners

Human Sorbin and SH3 Domain Containing 2 (Sorbs2) interaction partners

  1. SORBS2 transcription is activated by telomere position effect-over long distance upon telomere shortening in muscle cells from patients with facioscapulohumeral dystrophy

  2. ArgBP2 inhibits proliferation, migration, and invasion of gastric cancer cells.MORC2 down-regulates the ArgBP2 via histone methylation in gastric cancer cells.

  3. This study confirmed that SORBS2 as genetic modifiers of age at onset of Alzheimer disease.

  4. ArgBP2 interaction with alpha-actinin and actin stress fibers inhibits cell migration

  5. Tyrosine phosphorylation of ARGBP2 interferes with a SH3 mediated self-interaction, thereby controlling its panel of interacting partners and related functions.

  6. SORBS2 and TLR3 (show TLR3 Antibodies) induce premature senescence in primary human fibroblasts and keratinocytes.

  7. Sarcoplasmic sorbin and SH3 domain-containing protein 2 is released from damaged cardiac tissue into the bloodstream upon lethal acute myocardial infarction.

  8. In epithelial NMuMG cells, immunofluorescence analyses revealed localization of ArgBP2 at tight junctions and mutation analyses found a second SH3 domain (show ITSN1 Antibodies) to be important for ArgBP2 localization to the cell-cell contact sites.

  9. A co-localization of SORBS2 and eEF1A (show EEF1A1 Antibodies) was evidenced at level of plasma membrane, thus suggesting the involvement of eEF1A1 (show EEF1A1 Antibodies) in novel key signal transduction complexes.

  10. Reconstitution of SORBS2 expression resulted significant reduction in cell proliferation, colony formation and anchorage-independent growth in CaSki, HPKII and HaCaT cells, whereby anchorage-independent growth could only be investigated for CaSki cells

Mouse (Murine) Sorbin and SH3 Domain Containing 2 (Sorbs2) interaction partners

  1. The study screened CrkL (show CRKL Antibodies) binding proteins using RNA interference (RNAi) and identified Sorbs1 (show SORBS1 Antibodies) and Sorbs2 as two proteins that are enriched at AChR clusters and are required for the formation of AChR aggregation in vitro.

Sorbs2 Antigen Profile

Protein Summary

Arg and c-Abl represent the mammalian members of the Abelson family of non-receptor protein-tyrosine kinases. They interact with the Arg/Abl binding proteins via the SH3 domains present in the carboxy end of the latter group of proteins. This gene encodes the sorbin and SH3 domain containing 2 protein. It has three C-terminal SH3 domains and an N-terminal sorbin homology (SoHo) domain that interacts with lipid raft proteins. The subcellular localization of this protein in epithelial and cardiac muscle cells suggests that it functions as an adapter protein to assemble signaling complexes in stress fibers, and that it is a potential link between Abl family kinases and the actin cytoskeleton. Alternative splicing results in multiple transcript variants encoding different isoforms.

Gene names and symbols associated with Sorbs2

  • sorbin and SH3 domain containing 2 (sorbs2) antibody
  • sorbin and SH3 domain containing 2 (SORBS2) antibody
  • sorbin and SH3 domain containing 2 (LOC100231821) antibody
  • sorbin and SH3 domain containing 2 (Sorbs2) antibody
  • 2010203O03Rik antibody
  • 9430041O17RIK antibody
  • A530071H08 antibody
  • Argbp2 antibody
  • DKFZp468F1119 antibody
  • mKIAA0777 antibody
  • PRO0618 antibody

Protein level used designations for Sorbs2

sorbin and SH3 domain containing 2 , sorbin and SH3 domain-containing protein 2 , sorbin and SH3 domain-containing protein 2-like , Arg binding protein 2 , Arg/Abl-interacting protein 2 , Arg/Abl-interacting protein ArgBP2 , arg/Abl-interacting protein 2 , nArgBP2 , neural ArgBP2 , Sorbin and SH3 domain-containing protein 2 , sorbin polypeptide

GENE ID SPECIES
100196922 Xenopus (Silurana) tropicalis
461640 Pan troglodytes
696139 Macaca mulatta
100014403 Monodelphis domestica
100050682 Equus caballus
100153277 Sus scrofa
100172173 Pongo abelii
100231821 Taeniopygia guttata
100344295 Oryctolagus cuniculus
100413518 Callithrix jacchus
100469106 Ailuropoda melanoleuca
8470 Homo sapiens
234214 Mus musculus
114901 Rattus norvegicus
396719 Sus scrofa
482906 Canis lupus familiaris
614391 Bos taurus
100724374 Cavia porcellus
422719 Gallus gallus
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