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anti-Sortilin-Related VPS10 Domain Containing Receptor 1 (SORCS1) Antibodies

SORCS1 encodes one family member of vacuolar protein sorting 10 (VPS10) domain-containing receptor proteins. Additionally we are shipping SORCS1 Kits (5) and SORCS1 Proteins (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SORCS1 114815 Q8WY21
SORCS1 309533  
SORCS1 58178  
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Top anti-SORCS1 Antibodies at antibodies-online.com

Showing 10 out of 32 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated FACS, WB Western blot analysis of SORCS1 Antibody (N-term) (ABIN652682) in K562 cell line lysates (35 µg/lane). SORCS1 (arrow) was detected using the purified polyclonal antibody. SORCS1 Antibody (N-term)(ABIN652682) flow cytometric analysis of k562 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Alkaline Phosphatase (AP) FACS, ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Rabbit Un-conjugated FACS   200 μL Log in to see 8 to 10 Days
$713.17
Details
Human Rabbit HRP FACS, ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Rabbit Un-conjugated FACS, ELISA, WB 400 μL Log in to see 6 Days
$457.14
Details
Human Rabbit Un-conjugated FACS, WB   200 μL Log in to see 11 to 16 Days
$532.71
Details
Human Rabbit PE FACS, ELISA, WB   200 μL Log in to see 16 Days
$710.29
Details
Human Rabbit HRP ELISA, WB   200 μL Log in to see 16 Days
$710.29
Details
Human Rabbit FITC FACS, ELISA, WB   200 μL Log in to see 16 Days
$710.29
Details
Human Rat Un-conjugated FACS   100 μg Log in to see 10 to 12 Days
$298.95
Details

SORCS1 Antibodies by Reactivity, Application, Clonality and Conjugate

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Top referenced anti-SORCS1 Antibodies

  1. Human Monoclonal SORCS1 Primary Antibody for FACS - ABIN2656697 : Chollangi, Thompson, Ruiz, Gardner, Bruick: Hemerythrin-like domain within F-box and leucine-rich repeat protein 5 (FBXL5) communicates cellular iron and oxygen availability by distinct mechanisms. in The Journal of biological chemistry 2012 (PubMed)

More Antibodies against SORCS1 Interaction Partners

Human Sortilin-Related VPS10 Domain Containing Receptor 1 (SORCS1) interaction partners

  1. Data identified associations between single nucleotide polymorphisms in SORCS1 and renal function in large cohorts of European and African ancestry.

  2. The propeptide region of sorCS1 contains two separate sites for binding to sortilin (show SORT1 Antibodies). One of these sites is removed from human sorCS1 during processing.

  3. Genetic variation of the rs10884402 and rs950809 in intron 1 of SORCS1 is associated with late onset Alzheimer disease in the Chinese Han population.

  4. The genetic link between AD[Alzheimer's disease]and SORCS1 gene variations are influenced by ethnic background, sex and whether an individual has type 2 diabetes mellitus

  5. Our data suggested that SORCS1 was in interaction with APOE in the development of late-onset Alzheimer's disease in a Northern Han Chinese population

  6. suggest that genetic variation in SORCS1 is associated with memory performance

  7. the 4 recently reported SNPs,located near BNC2 (show BNC2 Antibodies), SORCS1, GSC (show GSC Antibodies) and WDR72 loci, affecting glycemic control in type 1 diabetes had no apparent effect on HbA1c in type 2 diabetes; but, for SORCS1 SNP, findings do not rule out possible relationship with HbA1c

  8. Dysfunction of SorCS1 may contribute to both the amyloid precursor protein (show APP Antibodies)/amyloidbeta disturbance underlying Alzheimer disease and the insulin (show INS Antibodies)/glucose disturbance underlying diabetes mellitus.

  9. SNP which is nearest to SORCS1 is highly significantly associated with glycemic control in individuals with type 1 diabetes

  10. human sorCS1 has three isoforms, sorCS1a-c, with completely different cytoplasmic tails and differential expression in tissues

Mouse (Murine) Sortilin-Related VPS10 Domain Containing Receptor 1 (SORCS1) interaction partners

  1. Male mice with either the APP (show APP Antibodies)/PSEN1 (show PSEN1 Antibodies) or Sorcs1 -/- genotype displayed earlier onset and persistent impairment in both glucose homeostasis and in learning behavior.

  2. SorCS1 and APP (show APP Antibodies) share trafficking pathways and that SorCS1c can retain APP (show APP Antibodies) from insertion into anterograde transport vesicles

  3. SorCs1 is a global protein trafficking regulator, including AMPA (show GRIA3 Antibodies) receptors and neurexins.

  4. SORCS1 is sufficient to promote secretory granule biogenesis in metabolically stressed beta cells

  5. SorCS3 (show SORCS3 Antibodies) and the homologous sorCS1 and sorCS2 (show SORCS2 Antibodies) genes were expressed in a combinatorial mostly non-overlapping pattern in the developing and mature central nervous system; activity-dependent induction of sorCS3 (show SORCS3 Antibodies) did not require protein synthesis

  6. identification of the Sorcs1 gene provides insight into the pathway underlying the pathophysiology of obesity-induced type 2 diabetes mellitus

  7. Different motifs regulate trafficking of Sorcs isoforms.

SORCS1 Antigen Profile

Protein Summary

This gene encodes one family member of vacuolar protein sorting 10 (VPS10) domain-containing receptor proteins. The VPS10 domain name comes from the yeast carboxypeptidase Y sorting receptor Vps10 protein. Members of this gene family are large with many exons but the CDS lengths are usually less than 3700 nt. Very large introns typically separate the exons encoding the VPS10 domain\; the remaining exons are separated by much smaller-sized introns. These genes are strongly expressed in the central nervous system. Two of the five family members (sortilin and sortilin-related receptor) are synthesized as preproproteins\; it is not yet known if this encoded protein is also a preproprotein. Alternatively spliced transcript variants encoding different isoforms have been identified.

Gene names and symbols associated with SORCS1

  • sortilin-related VPS10 domain containing receptor 1 (SORCS1) antibody
  • sortilin-related VPS10 domain containing receptor 1 (Sorcs1) antibody
  • VPS10 domain receptor protein SORCS 1 (Sorcs1) antibody
  • hSorCS antibody
  • mSorCS antibody
  • Sorcs antibody

Protein level used designations for SORCS1

VPS10 domain receptor protein SORCS 1 , VPS10 domain-containing receptor SorCS1

GENE ID SPECIES
114815 Homo sapiens
477816 Canis lupus familiaris
100155686 Sus scrofa
537536 Bos taurus
309533 Rattus norvegicus
58178 Mus musculus
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