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SNX14 encodes a member of the sorting nexin family. Additionally we are shipping SNX14 Proteins (4) and many more products for this protein.
Showing 10 out of 21 products:
Human Polyclonal SNX14 Primary Antibody for ICC, IF - ABIN4354983
Huang, Yoon, Brooks, Bakal, Berrios, Larsen, Wallace, Han, Chung, Zylka, Philpot: Snx14 regulates neuronal excitability, promotes synaptic transmission, and is imprinted in the brain of mice. in PLoS ONE 2014
A unique ataxia (show USP14 Antibodies) syndrome due to biallelic SNX14 mutations leading to lysosome-autophagosome dysfunction.
SNX19 (show SNX19 Antibodies) and SNX14 PX domains reveal key differences in spatial control of RGS (show PITX2 Antibodies)-PX proteins in cell signaling and trafficking.
Mutations in SNX14 cause a distinctive autosomal-recessive cerebellar ataxia (show USP14 Antibodies) and intellectual disability syndrome.
SNX14 is a dual endogenous negative regulator in 5-HT6R (show HTR6 Antibodies)-mediated signaling pathway.
These data reveal a role for monoallelic Snx14 expression in maintaining normal neuronal excitability and synaptic transmission.
This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. The encoded protein also contains a regulator of G protein signaling (RGS) domain. Regulator of G protein signaling family members are regulatory molecules that act as GTPase activating proteins for G alpha subunits of heterotrimeric G proteins. Two transcript variants encoding distinct isoforms have been identified for this gene.
, sorting nexin 14
, sorting nexin-14-like