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SNX18 encodes a member of the sorting nexin family. Additionally we are shipping SNX18 Antibodies (54) and SNX18 Proteins (4) and many more products for this protein.
SNX18 promotes autophagosome formation by virtue of its ability to remodel membranes and provide membrane to forming autophagosomes.
The sorting nexin 9 (SNX9 (show SNX9 ELISA Kits)) subfamily members - SNX9 (show SNX9 ELISA Kits), SNX18 and SNX33 - are required for progression and completion of mitosis.
FIP5-SNX18 complex plays a pivotal role in the polarized transport of apical proteins during apical lumen initiation in epithelial cells.
The results indicate that SNX9 (show SNX9 ELISA Kits)-family members make up discrete membrane-scission units together with dynamin (show DNM1 ELISA Kits), and suggest that SNX18 mediates budding of carriers for AP-1 (show FOSB ELISA Kits)-positive endosomal trafficking.
SNX18 may play an active role in axonal elongation
This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein does not contain a coiled coil region, like some family members, but contains a SH3 domain. Multiple transcript variants encoding different isoforms have been found for this gene.
sorting nexin 18
, sorting nexin associated golgi protein 1
, sorting nexin-18
, sorting nexin-18-like
, SH3 and PX domain-containing protein 3B
, sorting nexin-associated Golgi protein 1