anti-Sorting Nexin 27 (SNX27) Antibodies

SNX27 encodes a member of the sorting nexin family, a diverse group of cytoplasmic and membrane-associated proteins involved in endocytosis of plasma membrane receptors and protein trafficking through these compartments. Additionally we are shipping SNX27 Proteins (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SNX27 81609 Q96L92
SNX27 76742 Q3UHD6
SNX27 260323 Q8K4V4
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Top anti-SNX27 Antibodies at antibodies-online.com

Showing 10 out of 85 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of SNX27 (arrow) in 293 cell line lysates (35ug/lane) using Sorting nexin-27 (SNX27) 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p), SimWes, WB Western Blot: SNX27 Antibody [NBP1-45283] - Analysis of SNX27 on mouse brain extracts. Immunohistochemistry: SNX27 Antibody [NBP1-45283] - IHC analysis of SNX27 in mouse bladder using DAB with hematoxylin counterstain. 0.1 mL Log in to see 7 to 9 Days
$408.19
Details
Human Rabbit Un-conjugated WB Western blot analysis of SNX27 Antibody (Center) (ABIN653905) in 293 cell line lysates (35 µg/lane). SNX27 (arrow) was detected using the purified polyclonal antibody. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Cow Rabbit Un-conjugated WB Host: Rabbit Target Name: SNX27 Sample Type: Human Jurkat  Lane A: Primary Antibody  Lane B: Primary Antibody + Blocking Peptide  Primary Antibody Concentration: 1.0 ug/ml Peptide Concentration: 2.0 ug/ml Lysate Quantity: 25 ug/lane Host: Rabbit Target Name: SNX27 Sample Type: Jurkat Whole Cell lysates Antibody Dilution: 1.0ug/ml  SNX27 is supported by BioGPS gene expression data to be expressed in Jurkat 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p), WB Immunohistochemistry: SNX27 Antibody [NBP1-45282] - IHC analysis of SNX27 in mouse bladder using DAB with hematoxylin counterstain. Western Blot: SNX27 Antibody [NBP1-45282] - WB analysis of SNX27 in human liver. 0.1 mL Log in to see 7 to 9 Days
$381.94
Details
Human Rabbit Un-conjugated ELISA, WB   200 μL Log in to see 7 to 9 Days
$713.17
Details
Human Rabbit APC ELISA, WB   200 μL Log in to see 7 to 9 Days
$969.83
Details
Human Rabbit PE ELISA, WB   200 μL Log in to see 7 to 9 Days
$969.83
Details
Human Rabbit FITC ELISA, WB   200 μL Log in to see 7 to 9 Days
$969.83
Details
Human Rabbit Alkaline Phosphatase (AP) ELISA, WB   200 μL Log in to see 7 to 9 Days
$969.83
Details

SNX27 Antibodies by Reactivity, Application, Clonality and Conjugate

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Top referenced anti-SNX27 Antibodies

  1. Human Polyclonal SNX27 Primary Antibody for EIA, WB - ABIN954891 : Nassirpour, Slesinger: Subunit-specific regulation of Kir3 channels by sorting nexin 27. in Channels (Austin, Tex.) 2008 (PubMed)
    Show all 4 references for 954891

  2. Human Polyclonal SNX27 Primary Antibody for ICC, IF - ABIN4355011 : Ish-Shalom, Meirow, Sade-Feldman, Kanterman, Wang, Mizrahi, Klieger, Baniyash: Impaired SNX9 Expression in Immune Cells during Chronic Inflammation: Prognostic and Diagnostic Implications. in Journal of immunology (Baltimore, Md. : 1950) 2015 (PubMed)

More Antibodies against SNX27 Interaction Partners

Human Sorting Nexin 27 (SNX27) interaction partners

  1. This study defines specific acidic amino acid sequences upstream of the PDZ (show INADL Antibodies)-binding motif required for high-affinity engagement of the human SNX27 PDZ domain (show INADL Antibodies).

  2. a function of SNX27 in regulating beta-amyloid (Abeta (show APP Antibodies)) generation by modulating gamma-secretase activity.

  3. PTHR (show PTHLH Antibodies) recycles rapidly through at least two pathways, one involving the ASRT complex of actin, SNX27, and retromer and another possibly involving N-ethylmaleimide-sensitive factor (show NSF Antibodies).

  4. SNX27 inhibits the Wnt regulated transcription activity of TCF/LEF. Our results suggested that SNX27 interacts with Frizzled receptors to regulate the endocytosis and stability of Fzds

  5. SNX27 interaction with FAM21 is required for the precise localization of SNX27 at an endosomal subdomain.

  6. SNX27 deficiency is now added to the growing list of neurodegenerative disorders associated with retromer dysfunction.

  7. The results suggest that SNX27 undergoes dynamic partitioning between different membrane domains during immunological synapse assembly, and underscore the contribution of unique lipid interactions for SNX27 orchestration of cargo trafficking.

  8. The double knockdown of SNX17 (show SNX17 Antibodies) and SNX27 results in a striking reduction of papillomavirus 16 infection due to interruption of their binding to the L2 viral protein.

  9. RNAi-mediated suppression of ANKRD50 phenocopies loss of SNX27-retromer function.

  10. VPS26A (show VPS26A Antibodies) binding increases the affinity of the SNX27 PDZ domain (show INADL Antibodies) for PDZ (show INADL Antibodies)- binding motifs by an order of magnitude, revealing cooperativity in cargo selection.

Mouse (Murine) Sorting Nexin 27 (SNX27) interaction partners

  1. we anticipate that future study will determine whether modulation of a SNX27/Notch (show NOTCH1 Antibodies)/gamma-secretase pathway can also be of therapeutic interest to congenital hydrocephalus (show FOXC1 Antibodies)

  2. We identify binding and trafficking interactions between two of these factors, SORLA (show SORL1 Antibodies) and SNX27, and demonstrate that SNX27 can direct trafficking of SORLA (show SORL1 Antibodies) and the Abeta (show APP Antibodies) precursor APP (show APP Antibodies) to the cell surface to limit the production of Abeta (show APP Antibodies). Diversion APP (show APP Antibodies) to the cell surface through modulation of this molecular complex may represent a complimentary strategy for future development in AD treatment.

  3. A critical role for SNX27-retromer mediated transport of PTHR (show PTH1R Antibodies) in normal bone development.

  4. a function of SNX27 in regulating beta-amyloid (Abeta (show APP Antibodies)) generation by modulating gamma-secretase activity.

  5. VPS26A (show VPS26A Antibodies) binding increases the affinity of the SNX27 PDZ domain (show INADL Antibodies) for PDZ (show INADL Antibodies)- binding motifs by an order of magnitude, revealing cooperativity in cargo selection.

  6. SNX27-dependent mechanism of inhibitory plasticity in DA neurons is a potential intervention point for disorders of dopamine neurons.

  7. SNX27 associates with ZO-2 (show TJP2 Antibodies) and modulates the epithelial tight junction.

  8. a model by which SNX27 regulates trafficking of beta-Pix (show ARHGEF7 Antibodies) to focal adhesions and thereby influences cell motility.

  9. indicate that SNX27 may function to regulate endocytosis and/or endosomal sorting of NR2C (show GRIN2C Antibodies)

  10. SNX27 and NHERF (show SLC9A3R1 Antibodies) specifically interact with the 5-HT4a receptor splice variant

SNX27 Antigen Profile

Protein Summary

This gene encodes a member of the sorting nexin family, a diverse group of cytoplasmic and membrane-associated proteins involved in endocytosis of plasma membrane receptors and protein trafficking through these compartments. All members of this protein family contain a phosphoinositide binding domain (PX domain). A highly similar protein in mouse is responsible for the specific recruitment of an isoform of serotonin 5-hydroxytryptamine 4 receptor into early endosomes, suggesting the analogous role for the human protein.

Gene names and symbols associated with SNX27

  • sorting nexin family member 27 (SNX27) antibody
  • sorting nexin family member 27 (Snx27) antibody
  • 5730552M22Rik antibody
  • ESTM45 antibody
  • ESTM47 antibody
  • mKIAA0488 antibody
  • Mrt1 antibody
  • MY014 antibody
  • R75405 antibody

Protein level used designations for SNX27

methamphetamine-responsive transcript 1 , sorting nexin-27 , MAP-responsive gene protein , PDZ protein Mrt1 , PDZ-protein Mrt1 , methamphetamine (MAP) responsive transcript 1 , methamphetamine-responsive transcript 1 protein

GENE ID SPECIES
81609 Homo sapiens
76742 Mus musculus
260323 Rattus norvegicus
513214 Bos taurus
425666 Gallus gallus
483200 Canis lupus familiaris
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