Sorting Nexin 27 (SNX27) ELISA Kits

SNX27 encodes a member of the sorting nexin family, a diverse group of cytoplasmic and membrane-associated proteins involved in endocytosis of plasma membrane receptors and protein trafficking through these compartments. Additionally we are shipping SNX27 Antibodies (85) and SNX27 Proteins (5) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human SNX27 SNX27 81609 Q96L92
Anti-Mouse SNX27 SNX27 76742 Q3UHD6
Anti-Rat SNX27 SNX27 260323 Q8K4V4
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More ELISA Kits for SNX27 Interaction Partners

Human Sorting Nexin 27 (SNX27) interaction partners

  1. This study defines specific acidic amino acid sequences upstream of the PDZ (show INADL ELISA Kits)-binding motif required for high-affinity engagement of the human SNX27 PDZ domain (show INADL ELISA Kits).

  2. a function of SNX27 in regulating beta-amyloid (Abeta (show APP ELISA Kits)) generation by modulating gamma-secretase activity.

  3. PTHR (show PTHLH ELISA Kits) recycles rapidly through at least two pathways, one involving the ASRT complex of actin, SNX27, and retromer and another possibly involving N-ethylmaleimide-sensitive factor (show NSF ELISA Kits).

  4. SNX27 inhibits the Wnt regulated transcription activity of TCF/LEF. Our results suggested that SNX27 interacts with Frizzled receptors to regulate the endocytosis and stability of Fzds

  5. SNX27 interaction with FAM21 is required for the precise localization of SNX27 at an endosomal subdomain.

  6. SNX27 deficiency is now added to the growing list of neurodegenerative disorders associated with retromer dysfunction.

  7. The results suggest that SNX27 undergoes dynamic partitioning between different membrane domains during immunological synapse assembly, and underscore the contribution of unique lipid interactions for SNX27 orchestration of cargo trafficking.

  8. The double knockdown of SNX17 (show SNX17 ELISA Kits) and SNX27 results in a striking reduction of papillomavirus 16 infection due to interruption of their binding to the L2 viral protein.

  9. RNAi-mediated suppression of ANKRD50 phenocopies loss of SNX27-retromer function.

  10. VPS26A (show VPS26A ELISA Kits) binding increases the affinity of the SNX27 PDZ domain (show INADL ELISA Kits) for PDZ (show INADL ELISA Kits)- binding motifs by an order of magnitude, revealing cooperativity in cargo selection.

Mouse (Murine) Sorting Nexin 27 (SNX27) interaction partners

  1. we anticipate that future study will determine whether modulation of a SNX27/Notch (show NOTCH1 ELISA Kits)/gamma-secretase pathway can also be of therapeutic interest to congenital hydrocephalus (show FOXC1 ELISA Kits)

  2. We identify binding and trafficking interactions between two of these factors, SORLA (show SORL1 ELISA Kits) and SNX27, and demonstrate that SNX27 can direct trafficking of SORLA (show SORL1 ELISA Kits) and the Abeta (show APP ELISA Kits) precursor APP (show APP ELISA Kits) to the cell surface to limit the production of Abeta (show APP ELISA Kits). Diversion APP (show APP ELISA Kits) to the cell surface through modulation of this molecular complex may represent a complimentary strategy for future development in AD treatment.

  3. A critical role for SNX27-retromer mediated transport of PTHR (show PTH1R ELISA Kits) in normal bone development.

  4. a function of SNX27 in regulating beta-amyloid (Abeta (show APP ELISA Kits)) generation by modulating gamma-secretase activity.

  5. VPS26A (show VPS26A ELISA Kits) binding increases the affinity of the SNX27 PDZ domain (show INADL ELISA Kits) for PDZ (show INADL ELISA Kits)- binding motifs by an order of magnitude, revealing cooperativity in cargo selection.

  6. SNX27-dependent mechanism of inhibitory plasticity in DA neurons is a potential intervention point for disorders of dopamine neurons.

  7. SNX27 associates with ZO-2 (show TJP2 ELISA Kits) and modulates the epithelial tight junction.

  8. a model by which SNX27 regulates trafficking of beta-Pix (show ARHGEF7 ELISA Kits) to focal adhesions and thereby influences cell motility.

  9. indicate that SNX27 may function to regulate endocytosis and/or endosomal sorting of NR2C (show GRIN2C ELISA Kits)

  10. SNX27 and NHERF (show SLC9A3R1 ELISA Kits) specifically interact with the 5-HT4a receptor splice variant

SNX27 Antigen Profile

Antigen Summary

This gene encodes a member of the sorting nexin family, a diverse group of cytoplasmic and membrane-associated proteins involved in endocytosis of plasma membrane receptors and protein trafficking through these compartments. All members of this protein family contain a phosphoinositide binding domain (PX domain). A highly similar protein in mouse is responsible for the specific recruitment of an isoform of serotonin 5-hydroxytryptamine 4 receptor into early endosomes, suggesting the analogous role for the human protein.

Gene names and symbols associated with Sorting Nexin 27 (SNX27) ELISA Kits

  • sorting nexin family member 27 (SNX27) antibody
  • sorting nexin family member 27 (Snx27) antibody
  • 5730552M22Rik antibody
  • ESTM45 antibody
  • ESTM47 antibody
  • mKIAA0488 antibody
  • Mrt1 antibody
  • MY014 antibody
  • R75405 antibody

Protein level used designations for Sorting Nexin 27 (SNX27) ELISA Kits

methamphetamine-responsive transcript 1 , sorting nexin-27 , MAP-responsive gene protein , PDZ protein Mrt1 , PDZ-protein Mrt1 , methamphetamine (MAP) responsive transcript 1 , methamphetamine-responsive transcript 1 protein

GENE ID SPECIES
81609 Homo sapiens
76742 Mus musculus
260323 Rattus norvegicus
513214 Bos taurus
425666 Gallus gallus
483200 Canis lupus familiaris
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