Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
SP7 encodes a member of the Sp subfamily of Sp/XKLF transcription factors. Additionally we are shipping SP7 Antibodies (33) and SP7 Kits (21) and many more products for this protein.
Showing 3 out of 4 products:
FGF and Wnt (show WNT2 Proteins)/beta-Catenin (show CTNNB1 Proteins) pathways act in part by directing transcription of osx to promote osteoblast differentiation at sites of bone formation.
Data show the endogenous sp7 gene expression in the otic placode and vesicle, and in forming skeletal structures in Tg(sp7:EGFP)b1212 line.
Data suggest that beta-catenin (beta-cat) signaling upregulates the expression of osterix (OSX) in pre-osteoblastic and bone marrow stromal cells.
The 2 genes RUNX1 (show RUNX1 Proteins) and SP7 resulted differently expressed in cells cultured on metallic supports if compared with the expression recorded for OIC
c-Src (show SRC Proteins) signaling modulates osteoblast differentiation at least in part through phosphorylation of Osterix.
Pin1 (show PIN1 Proteins) regulates the osteogenic activity of Osterix.
Runx2 (show RUNX2 Proteins)-Sp7 molecular complex functionally cooperate for maximal induction of cell-phenotype-restricted genes
Osterix is a novel target of protein kinase A, and protein kinase A modulates osteoblast differentiation partially through the regulation of Osterix.
results provide a molecular description of a mechanism for Osx (show MID1 Proteins) and Runx2 (show RUNX2 Proteins) transcriptional cooperation that is subject to further regulation by MAPK (show MAPK1 Proteins)-activating signals during osteogenesis.
In adamantinomatous craniopharyngioma, Bmp2 (show BMP2 Proteins) was expressed primarily in the stellate reticulum and whorl-like array cells; Runx2 (show RUNX2 Proteins) and Osterix tended to be expressed in calcification-related epithelia.
MiR (show MLXIP Proteins)-31, controls Osterix expression through association to the 3' untranslated region of this transcription factor.
These results suggest that Osterix is a novel target of CaMKII (show CAMK2G Proteins) and the activity of Osterix can be modulated by a novel mechanism involving CaMKII (show CAMK2G Proteins) during osteoblast differentiation.
cells expressing osterix are mesenchymal progenitors contributing to all relevant cell types during morphogenesis.
Results propose that Utx (show KDM6A Proteins) plays important roles in osteoblast differentiation by controlling the expressions of Runx2 (show RUNX2 Proteins) and Osterix.
Decreased expression of Osterix, as well as impaired TGFbeta and BMP2 signaling, contribute to the observed osteopenic bone phenotype of TIEG1 KO mice.
Intermittent stretching promotes osteogenic differentiation of bone marrow derived mesenchymal stem cells; the p38MAPK (show MAPK14 Proteins)-osterix pathway has an important role in the control of osteogenesis related gene expression.
CHIP targets Osx for ubiquitination and degradation in osteoblasts after chronic exposure to TNF-alpha (show TNF Proteins).
conclude that OSX, one of the key downstream molecules of NFIC (show NFIC Proteins), plays a critical role in root, but not crown, formation
Cbl-b and c-Cbl regulate the degradation of Osterix through the ubiquitin-proteasome pathway.
The key role of Osx in control of cementoblast proliferation and differentiation is to maintain a low level of Wnt (show WNT2 Proteins)-beta-catenin (show CTNNB1 Proteins) via direct up-regulation of DKK1 (show DKK1 Proteins).
These data suggest that Osx-Cre containing controls should be used for both in vivo and in vitro skeletal analyses of conditional knockout mice generated with this Osx-Cre mouse strain
This gene encodes a member of the Sp subfamily of Sp/XKLF transcription factors. Sp family proteins are sequence-specific DNA-binding proteins characterized by an amino-terminal trans-activation domain and three carboxy-terminal zinc finger motifs. This protein is a bone specific transcription factor and is required for osteoblast differentiation and bone formation.
transcription factor Sp7
, transcription factor osterix
, Sp7 transcription factor
, transcription factor Sp7-like
, zinc finger protein osterix
, trans-acting transcription factor 7