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Transcriptional activator essential for osteoblast differentiation.
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osterix is a downstream target of IGF1R (show IGF1R ELISA Kits) in chondrocytes.
cells expressing osterix are mesenchymal progenitors contributing to all relevant cell types during morphogenesis.
Results propose that Utx (show KDM6A ELISA Kits) plays important roles in osteoblast differentiation by controlling the expressions of Runx2 (show RUNX2 ELISA Kits) and Osterix.
Decreased expression of Osterix, as well as impaired TGFbeta and BMP2 signaling, contribute to the observed osteopenic bone phenotype of TIEG1 KO mice.
Intermittent stretching promotes osteogenic differentiation of bone marrow derived mesenchymal stem cells; the p38MAPK (show MAPK14 ELISA Kits)-osterix pathway has an important role in the control of osteogenesis related gene expression.
c-Src (show SRC ELISA Kits) signaling modulates osteoblast differentiation at least in part through phosphorylation of Osterix.
CHIP targets Osx for ubiquitination and degradation in osteoblasts after chronic exposure to TNF-alpha (show TNF ELISA Kits).
conclude that OSX, one of the key downstream molecules of NFIC (show NFIC ELISA Kits), plays a critical role in root, but not crown, formation
Cbl-b and c-Cbl regulate the degradation of Osterix through the ubiquitin-proteasome pathway.
The key role of Osx in control of cementoblast proliferation and differentiation is to maintain a low level of Wnt (show WNT2 ELISA Kits)-beta-catenin (show CTNNB1 ELISA Kits) via direct up-regulation of DKK1 (show DKK1 ELISA Kits).
Transcriptional activator essential for osteoblast differentiation. Binds to SP1 and EKLF consensus sequences and to other G/C-rich sequences.
, trans-acting transcription factor 7
, transcription factor Sp7
, zinc finger protein osterix