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Sparc/osteonectin, Cwcv and Kazal-Like Domains Proteoglycan (Testican) 1 Proteins (SPOCK1)

SPOCK1 encodes the protein core of a seminal plasma proteoglycan containing chondroitin- and heparan-sulfate chains. Additionally we are shipping SPOCK1 Antibodies (32) and SPOCK1 Kits (3) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
SPOCK1 6695 Q08629
Rat SPOCK1 SPOCK1 306759  
SPOCK1 20745  
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Top SPOCK1 Proteins at antibodies-online.com

Showing 7 out of 8 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Baculovirus infected Insect Cells Human His tag 50 μg Log in to see 20 to 21 Days
$250.80
Details
HOST_HEK-293 Cells Human His tag Human Testican 1, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 85%. 100 μg Log in to see 2 to 3 Days
$286.00
Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 Days
$5,442.50
Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 Days
$5,442.50
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_HEK-293 Human His tag   0.1 mg Log in to see 2 to 3 Days
$515.63
Details
HOST_HEK-293 Cells Human Un-conjugated   10 μg Log in to see 2 to 3 Days
$105.00
Details

SPOCK1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , , ,
,
Mouse (Murine)

Top referenced SPOCK1 Proteins

  1. Human SPOCK1 Protein expressed in Baculovirus infected Insect Cells - ABIN2003172 : Edgell, Curiel, Hu, Marr: Efficient gene transfer to human endothelial cells using DNA complexed to adenovirus particles. in BioTechniques 1998 (PubMed)
    Show all 2 references for ABIN2003172

  2. Human SPOCK1 Protein expressed in HEK-293 Cells - ABIN2181787 : Alliel, Perin, Jollès, Bonnet: Testican, a multidomain testicular proteoglycan resembling modulators of cell social behaviour. in European journal of biochemistry / FEBS 1993 (PubMed)
    Show all 2 references for ABIN2181787

More Proteins for Sparc/osteonectin, Cwcv and Kazal-Like Domains Proteoglycan (Testican) 1 (SPOCK1) Interaction Partners

Human Sparc/osteonectin, Cwcv and Kazal-Like Domains Proteoglycan (Testican) 1 (SPOCK1) interaction partners

  1. SPOCK1 expression is significantly up-regulated in colorectal cancer tissues and associated with tumor size and stage. SPOCK1 stimulates the PI3K (show PIK3CA Proteins)/AKT (show AKT1 Proteins) signaling pathway to inhibit cell apoptosis and promote tumor growth.

  2. findings suggest that SPOCK1 is a critical mediator of tumor growth and metastasis in prostate cancer

  3. Knockdown of SPOCK1 inhibits the proliferation.

  4. This study suggests that SPOCK1 promotes proliferation, migration and invasion in glioma cells by activating PI3K (show PIK3CA Proteins)/AKT (show AKT1 Proteins) and Wnt (show WNT2 Proteins)/beta-catenin (show CTNNB1 Proteins) pathways, which provides a potential theoretical basis for clinical treatment of glioma.

  5. SPOCK1 is highly expressed in ovarian cancer.SPOCK1 contributes to ovarian cancer development and metastasis.

  6. These results suggest that up-regulation of SPOCK1 in ESCC induces EMT (show ITK Proteins), thus promotes migration and invasion in ESCC cells.

  7. Collectively, altered expression of PKP1 (show PKP1 Proteins) and SPOCK1 appears to be a frequent and critical event in prostate cancer

  8. SPOCK1 activates PI3K (show PIK3CA Proteins)/Akt (show AKT1 Proteins) signaling.

  9. Testican-1-induced EMT (show ITK Proteins) signaling.

  10. this study showed that SPOCK1 is a novel metastasis related biomarker in lung cancer and may be new diagnostic and therapeutic target for lung cancer.

Mouse (Murine) Sparc/osteonectin, Cwcv and Kazal-Like Domains Proteoglycan (Testican) 1 (SPOCK1) interaction partners

  1. results suggest a possibility that testican-1 plays a permissive role for regenerating axons in reactive astrocytes after injury

  2. SPARC (show SPARC Proteins) is counter-adhesive for murine lens epithelial cells. We also identify SPARC (show SPARC Proteins) as a modulator of LN-1 (show PHYH Proteins) secretion and deposition, an activity important in epithelial cell-ECM (show MMRN1 Proteins) interactions in the ocular lens.

  3. Testican-1 is not critical for mouse development [review]

SPOCK1 Protein Profile

Protein Summary

This gene encodes the protein core of a seminal plasma proteoglycan containing chondroitin- and heparan-sulfate chains. The protein's function is unknown, although similarity to thyropin-type cysteine protease-inhibitors suggests its function may be related to protease inhibition.

Gene names and symbols associated with SPOCK1

  • sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 (SPOCK1)
  • sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 (Spock1)
  • sparc/osteonectin, cwcv and kazal-like domains proteoglycan 1 (Spock1)
  • Spock protein
  • testican protein
  • TIC1 protein
  • Ticn1 protein

Protein level used designations for SPOCK1

sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 , sparc/osteonectin, cwcv and kazal-like domains proteoglycan 1 , testican-1 , testican-1-like , testican 1

GENE ID SPECIES
416304 Gallus gallus
462085 Pan troglodytes
511211 Bos taurus
715989 Macaca mulatta
100223935 Taeniopygia guttata
100398533 Callithrix jacchus
100443494 Pongo abelii
100478104 Ailuropoda melanoleuca
100542336 Meleagris gallopavo
100583164 Nomascus leucogenys
6695 Homo sapiens
474688 Canis lupus familiaris
100620623 Sus scrofa
306759 Rattus norvegicus
20745 Mus musculus
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