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anti-Spectrin Beta, Non-Erythrocytic 4 (SPTBN4) Antibodies

Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton, and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. Additionally we are shipping SPTBN4 Kits (10) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
Anti-Mouse SPTBN4 SPTBN4 80297  
Anti-Rat SPTBN4 SPTBN4 308458  
SPTBN4 57731 Q9H254
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Top anti-SPTBN4 Antibodies at antibodies-online.com

Showing 7 out of 8 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Goat Un-conjugated IHC (p) Human Brain, Cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 6 to 8 Days
$500.50
Details
Cow Goat Un-conjugated IHC (p) 50 μg Log in to see 11 to 13 Days
$541.80
Details
Human Goat Un-conjugated IHC   50 μg Log in to see 11 to 16 Days
$658.43
Details
Human Rabbit Un-conjugated ICC, IHC (fro), IHC (p), ELISA, WB   100 μg Log in to see 9 to 11 Days
$385.00
Details
Human Rabbit Un-conjugated IHC   0.1 mL Log in to see 8 to 11 Days
$439.69
Details
Human Goat Un-conjugated IHC (p)   50 μg Log in to see 6 to 8 Days
$467.50
Details
Human Rabbit Un-conjugated   100 μg Log in to see 29 to 34 Days
$574.35
Details

SPTBN4 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human , ,
,

More Antibodies against SPTBN4 Interaction Partners

Mouse (Murine) Spectrin Beta, Non-Erythrocytic 4 (SPTBN4) interaction partners

  1. In embryonic mouse axons neither beta4-spectrin nor Neurofascin (show NFASC Antibodies) control the distal-to-proximal restriction of AnkG (show ANK3 Antibodies).

  2. provide new insight into membrane targeting of TREK-1 (show KCNK2 Antibodies) in the heart and establish a broader role for beta(IV)-spectrin in organizing functional membrane domains critical for normal heart function

  3. Data indicate that betaIV-Spectrin-targeted CaMKII (show CAMK2G Antibodies) directly phosphorylates the inwardly-rectifying potassium channel (show KCNAB2 Antibodies), Kir6.2 (show KCNJ11 Antibodies).

  4. These findings demonstrate that spectrin cytoskeleton finely regulates ion channel distribution and implicates KCNQ2 (show KCNQ2 Antibodies)/3 subunits in axonal excitability and in myokymia etiology.

  5. identified a regulatory mechanism for Na(+) channels, via direct phosphorylation by beta(IV)-spectrin-targeted calcium/calmodulin-dependent kinase (show CAMK2 Antibodies) II

  6. Beta]IV-spectrin regulates sodium channel clustering through ankyrin-G (show ANK3 Antibodies) at axon initial segments and nodes of Ranvier

  7. Distinct protein domains of BetaIV spectrin regulate membrane stability and the molecular organization of nodes of Ranvier.

  8. BetaIVSigma1 spectrin, the only betaIV spectrin with an actin-binding domain, is an essential component of this coat. Specifically, betaIVSigma1 coexists with betaIVSigma6 at both axon initial segments and nodes of Ranvier.

  9. truncated betaIV-spectrin isoform Sigma6 plays a specific role in clustering voltage-gated sodium channels, whereas it is dispensable for membrane stabilization at axon initial segments and nodes of Ranvier.

  10. We identify a distinct protein domain in betaIV spectrin required for its localization to the AIS (show AR Antibodies), and show that this domain mediates betaIV spectrin's interaction with ankG (show ANK3 Antibodies).

SPTBN4 Antigen Profile

Protein Summary

Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton, and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. It is composed of two antiparallel dimers of alpha- and beta- subunits. This gene is one member of a family of beta-spectrin genes. The encoded protein localizes to the nuclear matrix, PML nuclear bodies, and cytoplasmic vesicles. A highly similar gene in the mouse is required for localization of specific membrane proteins in polarized regions of neurons. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with SPTBN4

  • spectrin beta, non-erythrocytic 4 (Sptbn4) antibody
  • spectrin, beta, non-erythrocytic 4 (Sptbn4) antibody
  • spectrin, beta, non-erythrocytic 4 (SPTBN4) antibody
  • spectrin, beta, non-erythrocytic 4 (LOC100342347) antibody
  • 1700022P15Rik antibody
  • 5830426A08Rik antibody
  • dyn antibody
  • lnd antibody
  • nmf261 antibody
  • nmf379 antibody
  • QV antibody
  • ROSA62 antibody
  • SpbIV antibody
  • SPNB4 antibody
  • SPTBN3 antibody

Protein level used designations for SPTBN4

spectrin beta 4 , quivering , beta-spectrin 4 , OTTMUSP00000028078 , neuroaxonal dystrophy , lumbosacral neuroaxonal dystrophy , spectrin, beta, non-erythrocytic 4 , beta-IV spectrin , spectrin beta chain, brain 3 , spectrin beta chain, non-erythrocytic 4 , spectrin, non-erythroid beta chain 3

GENE ID SPECIES
80297 Mus musculus
308458 Rattus norvegicus
57731 Homo sapiens
100626544 Sus scrofa
430775 Gallus gallus
100342347 Oryctolagus cuniculus
100724245 Cavia porcellus
Selected quality suppliers for anti-SPTBN4 (SPTBN4) Antibodies
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