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anti-Spectrin Repeat Containing, Nuclear Envelope 1 (SYNE1) Antibodies

SYNE1 encodes a spectrin repeat containing protein expressed in skeletal and smooth muscle, and peripheral blood lymphocytes, that localizes to the nuclear membrane. Additionally we are shipping SYNE1 Kits (4) and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SYNE1 23345 Q8NF91
SYNE1 64009 Q6ZWR6
SYNE1 499010  
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Top anti-SYNE1 Antibodies at antibodies-online.com

Showing 10 out of 14 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Mouse Rabbit Un-conjugated ICC, IF, IHC, IHC (fro), WB Immunofluorescence staining of anti-Nesprin1 in C2C12 myoblasts 0.1 mL Log in to see 5 to 6 Days
$455.84
Details
Mouse Mouse Un-conjugated ICC, IF, WB 0.1 mL Log in to see 5 to 6 Days
$455.84
Details
Human Rabbit Un-conjugated ICC, WB 100 μL Log in to see 8 to 10 Days
$676.50
Details
Human Mouse Un-conjugated ELISA, WB Western Blot detection against Immunogen (37.84 KDa) . 200 μL Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p)   0.1 mL Log in to see 8 to 11 Days
$439.69
Details
Human Mouse Un-conjugated ELISA, WB   100 μg Log in to see 8 to 10 Days
$537.17
Details
Human Mouse Un-conjugated ELISA, WB   50 μg Log in to see 11 to 16 Days
$561.00
Details
Human Mouse Un-conjugated ELISA   50 μL Log in to see 9 Days
$298.57
Details
Human Rabbit Un-conjugated ICC, IHC (fro), IHC (p), ELISA, WB   100 μg Log in to see 9 to 11 Days
$385.00
Details
Rat Mouse Un-conjugated WB Western Blot: SYNE1 Antibody (6A) [NBP2-22477] - Analysis of CPG2 is shown using adult rat brain fractions and whole cell lysates from mock or CPG2 transfected HEK293T cells (kindly provided by Elly Nedivi's lab, MIT, Cambridge, MA) onto a 4-20% Tris-HCl polyacrylamide gel. Proteins were transferred to a PVDF membrane and blocked with 5% Milk/TBST for at least 1 hour. Membranes were probed with a mouse monoclonal antibody recognizing CPG2 at a dilution of 1:1000 overnight at 4C on a rocking platform. Membranes were washed in TBS-0.1%Tween 20 and probed with a goat anti-mouse-HRP secondary antibody at a dilution of 1:20,000 for one hour. Membranes were washed and chemiluminescent detection performed using Super Signal West Dura. 0.1 mg Log in to see 6 to 9 Days
$408.19
Details

SYNE1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human , ,
,
,
Mouse (Murine)
,

Rat (Rattus)


Top referenced anti-SYNE1 Antibodies

  1. Mouse (Murine) Monoclonal SYNE1 Primary Antibody for ICC, IF - ABIN108653 : Korkhov, Zuber: Direct observation of molecular arrays in the organized smooth endoplasmic reticulum. in BMC cell biology 2009 (PubMed)
    Show all 3 references for ABIN108653

  2. Human Polyclonal SYNE1 Primary Antibody for ICC, IF - ABIN4357268 : Göb, Schmitt, Benavente, Alsheimer: Mammalian sperm head formation involves different polarization of two novel LINC complexes. in PLoS ONE 2010 (PubMed)

More Antibodies against SYNE1 Interaction Partners

Human Spectrin Repeat Containing, Nuclear Envelope 1 (SYNE1) interaction partners

  1. A full length transcript homologous to rat CPG2 exists within human SYNE1. A full length transcript homologous to rat CPG2 exists within human SYNE1.

  2. SNP rs79575945 in ESR1 (show ESR1 Antibodies) gene is associated with cancers of endometrioid subtype and resulted in the expression of SYNE1.

  3. Mechanostimulation mediates nuclear changes in oligodendrocyte progenitor cells via the SYNE1 complex.

  4. our data suggest that SYNE1 and FOXE1 (show FOXE1 Antibodies) are promising markers for colorectal cancer detection.

  5. Drosophila melanogaster larval muscles, exhibiting both elastic features contributed by the stretching capacity of MSP300 (nesprin) and rigidity provided by a perinuclear network of microtubules stabilized by Shot (show SHOX2 Antibodies) (spectraplakin) and EB1 (show MAPRE2 Antibodies).

  6. ur results show that SNPs rs9371601 and rs3093664 in the SYNE1 and TNF (show TNF Antibodies) genes respectively, are associated with menstrual migraine.

  7. A report of a family with a SYNE1 gene mutation that seems to cause an "Emery-Dreifuss muscular dystrophy-like" phenotype.

  8. nesprin-1 and nesprin-2 (show SYNE2 Antibodies) both regulate nuclear and cytoplasmic architecture.

  9. a role for Nesprin-1 in the DNA damage response pathway

  10. FOXE1 (show FOXE1 Antibodies) and SYNE1 hypermethylation markers demonstrated significantly increased expression in neoplastic tissue.

Mouse (Murine) Spectrin Repeat Containing, Nuclear Envelope 1 (SYNE1) interaction partners

  1. Results suggest that the loss of function of KASH-LESS variant of Nesprin1 giant resulting from Nesprin1 nonsense mutations underlies the molecular etiology of autosomal recessive cerebellar ataxia (show USP14 Antibodies) Type I.

  2. Disruption of both nesprin 1 and desmin (show DES Antibodies) results in decreased lifespan, body weight and muscle strength.

  3. nesprin-dependent recruitment of kinesin-1 to the nuclear envelope through the interaction of a conserved LEWD motif with kinesin light chain might be a general mechanism for cell-type-specific nuclear positioning during development.

  4. a role for Nesprin-1 in the DNA damage response pathway

  5. Loss of Nesprin 1 or 2, or both, led to impairment of gene expression changes in response to biomechanical stimuli. These data suggest a model whereby biomechanical signals are communicated from proteins of the outer nuclear membrane

  6. Nesprin-1 played important roles in mouse embryonic stem cell differentiation into cardiomyocytes.

  7. Data show that low expression of Syne1 splicing isoforms accounts for the wider and irregular nuclear envelope inter-membrane space in embryonic stem cells.

  8. Nesprin 1 is essential for normal positioning and anchorage of nuclei in skeletal muscle.

  9. The Nesprin-1 is essential for the interaction with a C-terminal region in SUN1 (show SUN1 Antibodies) protein.

  10. SUN1 (show SUN1 Antibodies) interacts with nuclear lamin A (show LMNA Antibodies) and cytoplasmic nesprins (nesprin-1 and nesprin-2 (show SYNE2 Antibodies))to provide a physical connection between the nuclear lamina and the cytoskeleton.

SYNE1 Antigen Profile

Protein Summary

This gene encodes a spectrin repeat containing protein expressed in skeletal and smooth muscle, and peripheral blood lymphocytes, that localizes to the nuclear membrane. Mutations in this gene have been associated with autosomal recessive spinocerebellar ataxia 8, also referred to as autosomal recessive cerebellar ataxia type 1 or recessive ataxia of Beauce. Alternatively spliced transcript variants encoding different isoforms have been described.

Gene names and symbols associated with SYNE1

  • spectrin repeat containing, nuclear envelope 1 (SYNE1) antibody
  • chromosome 6 open reading frame 98 (C6orf98) antibody
  • spectrin repeat containing, nuclear envelope 1 (syne1) antibody
  • spectrin repeat containing, nuclear envelope 1 (LOC100347993) antibody
  • spectrin repeat containing, nuclear envelope 1 (Syne1) antibody
  • 8B antibody
  • A330049M09Rik antibody
  • ARCA1 antibody
  • BE692247 antibody
  • C6orf98 antibody
  • C130039F11Rik antibody
  • CPG2 antibody
  • dJ45H2.2 antibody
  • EDMD4 antibody
  • MGC160118 antibody
  • mKIAA1756 antibody
  • Myne-1 antibody
  • Myne1 antibody
  • Nesp1 antibody
  • SCAR8 antibody
  • SYNE1 antibody

Protein level used designations for SYNE1

spectrin repeat containing, nuclear envelope 1 , chromosome 6 open reading frame 98 , nesprin-1-like , enaptin , myocyte nuclear envelope protein 1 , nesprin 1 , nesprin-1 , nuclear envelope spectrin repeat-1 , synaptic nuclear envelope protein 1 , synaptic nuclei expressed gene 1 , enaptin165 , myne-1 , nuclear envelope spectrin repeat protein 1 , synaptic nuclear envelope 1

GENE ID SPECIES
353348 Bos taurus
421640 Gallus gallus
484037 Canis lupus familiaris
711782 Macaca mulatta
784046 Bos taurus
100145637 Xenopus (Silurana) tropicalis
100347993 Oryctolagus cuniculus
100386277 Callithrix jacchus
100484267 Ailuropoda melanoleuca
100515591 Sus scrofa
100542938 Meleagris gallopavo
100552802 Anolis carolinensis
23345 Homo sapiens
64009 Mus musculus
499010 Rattus norvegicus
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