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SPAM1 Proteins

(Sperm Adhesion Molecule 1 (PH-20 Hyaluronidase, Zona Pellucida Binding) (SPAM1))
Hyaluronidase degrades hyaluronic acid, a major structural proteoglycan found in extracellular matrices and basement membranes. Six members of the hyaluronidase family are clustered into two tightly linked groups on chromosome 3p21.3 and 7q31.3. This gene was previously referred to as HYAL1 and HYA1 and has since been assigned the official symbol SPAM1\; another family member on chromosome 3p21.3 has been assigned HYAL1. This gene encodes a GPI-anchored enzyme located on the human sperm surface and inner acrosomal membrane. This multifunctional protein is a hyaluronidase that enables sperm to penetrate through the hyaluronic acid-rich cumulus cell layer surrounding the oocyte, a receptor that plays a role in hyaluronic acid induced cell signaling, and a receptor that is involved in sperm-zona pellucida adhesion. Abnormal expression of this gene in tumors has implicated this protein in degradation of basement membranes leading to tumor invasion and metastasis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010].
SPAM1 Protein (AA 346-445) (GST tag) SPAM1 Protein (AA 346-445) (GST tag) SPAM1 Protein (AA 346-445) (GST tag) (ABIN1321072)

SPAM1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA

SPAM1 Protein (AA 1-509) (GST tag) SPAM1 Protein (AA 1-509) (GST tag) SPAM1 Protein (AA 1-509) (GST tag) (ABIN1321071)

SPAM1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA

SPAM1 Protein (AA 36-490) (His tag) SPAM1 Protein (AA 36-490) (His tag) SPAM1 Protein (AA 36-490) (His tag) (ABIN3081716)

Crystallography grade SPAM1 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys

SPAM1 Proteins by Grade

Find SPAM1 Proteins with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

SPAM1 Proteins by Origin

Find SPAM1 Proteins for a variety of species such as anti-Human SPAM1, anti-Cynomolgus SPAM1, anti-Guinea Pig SPAM1. The species listed below are among those available. Click on a link to go to the corresponding products.

SPAM1 Proteins by Source

Here you will find SPAM1 Proteins proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

SPAM1 Proteins by Protein Type

Here you can find SPAM1 Proteins proteins categorized by available protein types. Additional protein types can be located using our search function.

SPAM1 Proteins by Application

Find SPAM1 Proteins validated for a specific application such as ELISA, WB, SDS, AP. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular SPAM1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1321072
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1321071
Quantity 25 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3081716
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7422409
Quantity 100 μg
Datasheet Datasheet
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7422412
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
Cat. No. ABIN6964321
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2732494
Quantity 20 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2181785
Quantity 200 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
Cat. No. ABIN7199566
Quantity 200 μg
Datasheet Datasheet
Reactivity Cynomolgus
Source Yeast
Validations
Cat. No. ABIN1610527
Quantity 1 mg
Datasheet Datasheet
Reactivity Guinea Pig
Source Yeast
Validations
Cat. No. ABIN1461869
Quantity 1 mg
Datasheet Datasheet

Aliases for SPAM1 Proteins

sperm adhesion molecule 1 (Spam1) Proteins
sperm adhesion molecule 1 (SPAM1) Proteins
sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding) L homeolog (spam1.L) Proteins
sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding) (SPAM1) Proteins
sperm adhesion molecule 1 (spam1) Proteins
AV039194 Proteins
HYA1 Proteins
HYAL1 Proteins
HYAL3 Proteins
HYAL5 Proteins
im:6902904 Proteins
Ph-20 Proteins
PH-20 Proteins
PH20 Proteins
SPAG15 Proteins
Spam Proteins
spam1 Proteins
XEH1 Proteins
zgc:158668 Proteins
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