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Sperm Associated Antigen 1 Proteins (SPAG1)

The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Additionally we are shipping Sperm Associated Antigen 1 Antibodies (49) and Sperm Associated Antigen 1 Kits (4) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
SPAG1 6674 Q07617
SPAG1 26942 Q80ZX8
Rat SPAG1 SPAG1 315033 Q5U2X2
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Top Sperm Associated Antigen 1 Proteins at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

SPAG1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

More Proteins for Sperm Associated Antigen 1 (SPAG1) Interaction Partners

Human Sperm Associated Antigen 1 (SPAG1) interaction partners

  1. SPAG1 probably plays a role in the cytoplasmic assembly.

  2. The h-Sp-1 molecule is expressed in sperm and testes and plays a role in fertilization.

  3. HSD-3.8 (SPAG1), interacts with G-protein beta 1 subunit (show GNB1 Proteins) and activates extracellular signal-regulated kinases 1 and 2

  4. Immunocytochemical analysis demonstrated colocalization of SPAG1 with microtubules, and their association was confirmed by co-immunoprecipitation; subsequent motility assays further substantiated a potential role of SPAG1 in cancer cell motility

Mouse (Murine) Sperm Associated Antigen 1 (SPAG1) interaction partners

  1. The number of PCR positives of sperm mtDNA in two-cell embryos was significantly increased following sperm incubation with anti-tetratricopeptide repeat-containing protein involved in spermatogenesis (tpis).

Sperm Associated Antigen 1 (SPAG1) Protein Profile

Protein Summary

The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein expressed by this gene is recognized by anti-sperm agglutinating antibodies from an infertile woman. Furthermore, immunization of female rats with the recombinant human protein reduced fertility. This protein localizes to the plasma membrane of germ cells in the testis and to the post-acrosomal plasma membrane of mature spermatozoa. Recombinant polypeptide binds GTP and exhibits GTPase activity. Thus, this protein may regulate GTP signal transduction pathways involved in spermatogenesis and fertilization. Two transcript variants of this gene encode the same protein.

Gene names and symbols associated with SPAG1

  • sperm associated antigen 1 (SPAG1)
  • sperm associated antigen 1 (spag1)
  • sperm associated antigen 1 (CpipJ_CPIJ006297)
  • sperm associated antigen 1 (Spag1)
  • cb1089 protein
  • HSD-3.8 protein
  • MGC162178 protein
  • SP75 protein
  • TPIS protein
  • wu:fj78g10 protein

Protein level used designations for SPAG1

sperm associated antigen 1 , sperm-associated antigen 1 , TPR-containing protein involved in spermatogenesis , infertility-related sperm protein Spag-1 , tetratricopeptide repeat-containing protein , HSD-3.8

GENE ID SPECIES
420249 Gallus gallus
464314 Pan troglodytes
564953 Danio rerio
607063 Canis lupus familiaris
6038177 Culex quinquefasciatus
100038144 Xenopus (Silurana) tropicalis
6674 Homo sapiens
26942 Mus musculus
315033 Rattus norvegicus
530104 Bos taurus
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