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SPAG8 Proteins

(Sperm Associated Antigen 8 (SPAG8))

The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein encoded by this gene is recognized by sperm agglutinating antibodies from an infertile woman. This protein is localized in germ cells of the testis at all stages of spermatogenesis and is localized to the acrosomal region of mature spermatozoa. This protein interacts with ACT (activator of CREM in testis) and may play a role in CREM (cAMP response element modulator)-ACT-mediated gene transcription during spermatogenesis. This protein may also play a role in spermatogenesis by regulating microtubule formation and cell division. Alternatively spliced variants that encode different protein isoforms have been described but the full-length sequences of only two have been determined. [provided by RefSeq, Jul 2012].

recommended

SPAG8 Protein (AA 321-421) (GST tag) (ABIN1321065)

SPAG8 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA

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recommended

SPAG8 Protein (AA 1-501) (GST tag) (ABIN1321064)

SPAG8 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA

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recommended

SPAG8 Protein (AA 1-426) (His tag) (ABIN3095537)

Crystallography grade SPAG8 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, Crys, SDS

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SPAG8 Proteins by Grade

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SPAG8 Proteins by Origin

Find SPAG8 Proteins for a variety of species such as anti-Human SPAG8, anti-Mouse SPAG8. The species listed below are among those available. Click on a link to go to the corresponding products.

SPAG8 Proteins by Source

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SPAG8 Proteins by Protein Type

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SPAG8 Proteins by Application

Find SPAG8 Proteins validated for a specific application such as ELISA, WB, AP, AA. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular SPAG8 Proteins

Product

Reactivity

Source

Validations

Cat. No.

Quantity

Datasheet

SPAG8 Protein (AA 321-421) (GST tag)

Reactivity Human

Source Wheat germ

Validations

Cat. No. ABIN1321065

Quantity 10 μg

Datasheet Datasheet

SPAG8 Protein (AA 1-501) (GST tag)

Reactivity Human

Source Wheat germ

Validations

Cat. No. ABIN1321064

Quantity 25 μg

Datasheet Datasheet

SPAG8 Protein (AA 1-426) (His tag)

Reactivity Human

Source Insect Cells

Validations

Cat. No. ABIN3095537

Quantity 1 mg

Datasheet Datasheet

SPAG8 Protein (AA 1-470) (His tag)

Reactivity Mouse

Source Insect Cells

Validations

Cat. No. ABIN3135120

Quantity 1 mg

Datasheet Datasheet

Aliases for SPAG8 Proteins

sperm associated antigen 8 (SPAG8) Proteins
sperm associated antigen 8 (Spag8) Proteins
BS-84 Proteins
HSD-1 Proteins
hSMP-1 Proteins
MH-SPAG8 Proteins
SMP1 Proteins
SPAG3 Proteins

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SPAG8 Proteins by Grade

SPAG8 Proteins by Origin

SPAG8 Proteins by Source

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SPAG8 Proteins by Application

Popular SPAG8 Proteins

Aliases for SPAG8 Proteins

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