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Sperm Autoantigenic Protein 17 Proteins (SPA17)

SPA17 encodes a protein present at the cell surface. Additionally we are shipping SPA17 Antibodies (57) and SPA17 Kits (30) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
SPA17 53340 Q15506
SPA17 20686 Q62252
Rat SPA17 SPA17 85244  
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Top SPA17 Proteins at antibodies-online.com

Showing 10 out of 13 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human GST tag 50 μg Log in to see 21 to 26 Days
$341.00
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Rabbit His tag   1 mg Log in to see 56 to 66 Days
$2,317.33
Details
Yeast Macaca fascicularis His tag   1 mg Log in to see 56 to 66 Days
$2,333.83
Details
Yeast Macropus eugenii His tag   1 mg Log in to see 56 to 66 Days
$2,339.33
Details
Yeast Primates His tag   1 mg Log in to see 56 to 66 Days
$2,370.50
Details
Yeast REACT_Opossum His tag   1 mg Log in to see 56 to 66 Days
$2,420.00
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 3 to 4 Days
$382.86
Details

SPA17 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

More Proteins for Sperm Autoantigenic Protein 17 (SPA17) Interaction Partners

Human Sperm Autoantigenic Protein 17 (SPA17) interaction partners

  1. dendritic cells from human umbilical cord blood modulated for SP17 expression induced antigen-specific anti-tumor immunity against SP17(+) non-small cell lung cancer.

  2. SP17/AKAP4 (show AKAP4 Proteins)/PTTG1 (show PTTG1 Proteins) are expressed in both human NSCLC cell lines and primary tumors and can elicit an immunogenic response in lung cancer patients.

  3. NY-ESO-1 (show CTAG1B Proteins) and SP17 was not significantly associated with a specific histotype, but high-level GAGE expression was more frequent in squamous cell carcinoma. GAGE expression was demonstrated to be significantly higher in stage II-IIIa than stage I NSCLC.

  4. Sp17 is highly expressed in hepatocellular carcinoma cells

  5. SP17 was expressed in many cancer types with an overall frequency of 12%. SP17 was most frequently expressed in a different set of cancer types than MAGE (show MAGEB10 Proteins)-A and GAGE antigens and rarely overlapped with these proteins.

  6. Sperm protein 17 is highly expressed in endometrial and cervical cancers.

  7. Data show that cisplatin induced decrease in Sp17 levels was due to transcriptional inhibition and cisplatin-resistant cell lines did not show this decrease in Sp17 levels in response to cisplatin treatment.

  8. Sp17 has different expression patterns in cancer cell lines as compared to normal non-testes tissues and a potential pathogenic role in diseased cells

  9. expression of Sp17, a thought to be gamete-specific protein, in the synoviocytes of 8/8 female rheumatoid arthritis patients

  10. identification of a nonapeptide sequence within the Sp17 protein that is predicted to have a high binding affinity for HLA-A1 molecules

Mouse (Murine) Sperm Autoantigenic Protein 17 (SPA17) interaction partners

  1. mRBMY protein can bind to the testis and sperm-specific spa17 mRNA.

  2. Spa17 is most abundantly expressed in tissues rich in highly ciliated cells, such as olfactory sensory neurons, and is predicted to be important to cilia.

SPA17 Protein Profile

Protein Summary

This gene encodes a protein present at the cell surface. The N-terminus has sequence similarity to human cAMP-dependent protein kinase A (PKA) type II alpha regulatory subunit (RIIa) while the C-terminus has an IQ calmodulin-binding motif. The central portion of the protein has carbohydrate binding motifs and likely functions in cell-cell adhesion. The protein was initially characterized by its involvement in the binding of sperm to the zona pellucida of the oocyte. Recent studies indicate that it is also involved in additional cell-cell adhesion functions such as immune cell migration and metastasis. A retrotransposed pseudogene is present on chromosome 10q22.

Gene names and symbols associated with SPA17

  • sperm autoantigenic protein 17 (spa17)
  • sperm autoantigenic protein 17 (SPA17)
  • sperm autoantigenic protein 17 (Spa17)
  • CT22 protein
  • MGC89454 protein
  • Sp17 protein
  • SP17-1 protein
  • SPA17 protein

Protein level used designations for SPA17

sperm autoantigenic protein 17 , sperm protein 17 , sperm surface protein Sp17 , cancer/testis antigen 22 , band 34 , SP17

GENE ID SPECIES
448437 Xenopus (Silurana) tropicalis
479402 Canis lupus familiaris
574157 Macaca mulatta
616974 Bos taurus
791101 Ornithorhynchus anatinus
100505447 Xenopus laevis
53340 Homo sapiens
20686 Mus musculus
85244 Rattus norvegicus
100009312 Oryctolagus cuniculus
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