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The encoded protein is a human alloantigen involved in sperm-egg binding and fusion. Additionally we are shipping SPESP1 Proteins (7) and SPESP1 Kits (4) and many more products for this protein.
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Human Polyclonal SPESP1 Primary Antibody for WB - ABIN531416
Baibakov, Boggs, Yauger, Baibakov, Dean: Human sperm bind to the N-terminal domain of ZP2 in humanized zonae pellucidae in transgenic mice. in The Journal of cell biology 2012
Equatorial segment protein (ESP), a novel 349-amino acid concanavalin-A-binding protein encoded by a two-exon gene (SP-ESP) located on chromosome 15 at q22, has been localized to the equatorial segment of ejaculated human sperm.
The present study identified SPESP1 in the acrosome as the primary binding target of Peanut agglutinin (PNA) in the mouse testis. Further defining the specific lectin-glycoprotein relationships in individual cells will enhance the value of lectin histochemistry.
SPESP1 is necessary to produce the fully 'fusion competent' sperm.
The encoded protein is a human alloantigen involved in sperm-egg binding and fusion.
sperm equatorial segment protein 1
, equatorial segment protein
, glycosylated 38 kDa sperm protein C-7/8