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Sphingosine-1-Phosphate Lyase 1 (SGPL1) ELISA Kits

Cleaves phosphorylated sphingoid bases (PSBs), such as sphingosine-1-phosphate, into fatty aldehydes and phosphoethanolamine. Additionally we are shipping SGPL1 Antibodies (40) and SGPL1 Proteins (9) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
SGPL1 20397 Q8R0X7
SGPL1 8879 O95470
SGPL1 286896 Q8CHN6
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Top SGPL1 ELISA Kits at antibodies-online.com

Showing 3 out of 8 products:

Catalog No. Reactivity Sensitivity Range Quantity Supplier Delivery Price Details
Mouse 0.055 ng/mL 0.15-10 ng/mL 96 Tests Log in to see 9 to 11 Days
$757.89
Details
Human 78-5000 pg/mL 96 Tests Log in to see 11 to 13 Days
$1,029.60
Details
Rat
96 Tests Log in to see 11 to 13 Days
$875.60
Details

More ELISA Kits for SGPL1 Interaction Partners

Mouse (Murine) Sphingosine-1-Phosphate Lyase 1 (SGPL1) interaction partners

  1. Studies suggest that S1PL is a novel endogenous suppressor of pulmonary fibrosis in human idiopathic pulmonary fibrosis and animal models.

  2. Although the observed inhibitory effect was not as strong as that of 4-deoxypyridoxine (a VB6 analog SPL inhibitor), these findings may be useful for further understanding the mechanism of action of THI.

  3. upregulation of multidrug resistance transporters contributes to the chemoresistance of S1P (show S1PR1 ELISA Kits) lyase-deficient MEFs

  4. Sphingosine-1-phosphate lyase downregulation promotes colon carcinogenesis through STAT3 (show STAT3 ELISA Kits)-activated microRNAs.

  5. Findings suggest that sphingosine phosphate lyase (S1P (show S1PR1 ELISA Kits) lyase) expressed in the thymic medullary perivascular spaces keeps the tissue sphingosine 1-phosphate low around the vessels and promotes thymic egress via up-regulation of S1P receptor 1 (S1P1 (show S1PR1 ELISA Kits)).

  6. Data indicate that SGPL1 sphingosine 1-phosphate lyase (aldolase (show ALD ELISA Kits)) mRNA is significantly increased in the periinfarct cortex.

  7. Leukocyte Sgpl1 as critical factor in monocyte macrophage differentiation and function.

  8. Inducible Sgpl1 knockout mice are protected in experimental autoimmune encephalomyelitis (EAE).

  9. S1PL deficiency increases sphingolipid formation via recycling at the expense of de novo biosynthesis in neurons.

  10. Data show that S1P (show S1PR1 ELISA Kits) lyase knockout mice with reduced S1P (show S1PR1 ELISA Kits) lyase activity (resulting in increased bio-available S1P (show S1PR1 ELISA Kits)) had improved survival compared with wild-type littermates.

Human Sphingosine-1-Phosphate Lyase 1 (SGPL1) interaction partners

  1. increased SK and SPL mRNA expression along with reduced sphingosine 1-phosphate levels were more commonly observed in hepatocellular carcinoma tissues.

  2. SPHK1 (show SPHK1 ELISA Kits):SGPL1 ratio correlated with increased cellular sphingosine-1-phosphate (S1P (show MBTPS1 ELISA Kits)), and S1P (show MBTPS1 ELISA Kits) correlated with drug resistance (IC50).

  3. Results show that dissociation of SHP-1 (show PTPN6 ELISA Kits) from spinophilin (show PPP1R9B ELISA Kits) is followed by an increase in the binding of spinophilin (show PPP1R9B ELISA Kits) to PP1 (show PPA1 ELISA Kits).

  4. Sphingosine-1-phosphate lyase downregulation promotes colon carcinogenesis through STAT3 (show STAT3 ELISA Kits)-activated microRNAs.

  5. S1P (show MBTPS1 ELISA Kits) lyase - by facilitating S1P1 (show S1PR1 ELISA Kits) receptor recycling - is essential for S1P (show MBTPS1 ELISA Kits)-mediated sustained signaling

  6. results highlight the importance of S1P (show MBTPS1 ELISA Kits) in AD suggesting the existence of a global deregulation of S1P (show MBTPS1 ELISA Kits) signaling in this disease from its synthesis by SphK1 (show SPHK1 ELISA Kits) and degradation by SPL to its signaling by the S1P1 (show S1PR1 ELISA Kits) receptor.

  7. The cells expressing SGPL1 in the parenchyma were CD68 (show CD68 ELISA Kits)(+) APCs (show APCS ELISA Kits).

  8. Data show that a easy assay for 2-hydroxyacyl-CoA lyase (HACL1 (show HACL1 ELISA Kits)) and sphingosine-1-phosphate lyase (SGPL1) activities was developed.

  9. SPL expression and activity are downregulated in cancerous tissues, there is a relationship between loss of SPL expression and prostate cancer aggressiveness.

  10. S1P (show MBTPS1 ELISA Kits)(ext (show EXT1 ELISA Kits)) mediated endothelial cell motility is dependent on intracellular S1P (show MBTPS1 ELISA Kits) production, which is regulated, in part, by SphK1 (show SPHK1 ELISA Kits) and S1PL.

SGPL1 Antigen Profile

Antigen Summary

Cleaves phosphorylated sphingoid bases (PSBs), such as sphingosine-1-phosphate, into fatty aldehydes and phosphoethanolamine. Elevates stress-induced ceramide production and apoptosis.

Gene names and symbols associated with SGPL1

  • sphingosine-1-phosphate lyase 1 (SGPL1) antibody
  • sphingosine-1-phosphate lyase 1 (sgpl1) antibody
  • sphingosine phosphate lyase 1 (Sgpl1) antibody
  • sphingosine-1-phosphate lyase 1 (Sgpl1) antibody
  • AI428538 antibody
  • D10Xrf456 antibody
  • S1PL antibody
  • SGPL1 antibody
  • Spgl1 antibody
  • spl antibody
  • zgc:162153 antibody

Protein level used designations for SGPL1

sphingosine-1-phosphate lyase 1 , spl , SP-lyase 1 , SPL 1 , mSPL , sphingosine-1-phosphate aldolase , hSPL , sphingosine phosphate lyase 1

GENE ID SPECIES
100072755 Equus caballus
423714 Gallus gallus
100037007 Xenopus laevis
100037312 Danio rerio
20397 Mus musculus
8879 Homo sapiens
522515 Bos taurus
286896 Rattus norvegicus
489032 Canis lupus familiaris
100525187 Sus scrofa
100173995 Pongo abelii
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