You are viewing an incomplete version of our website. Please click to reload the website as full version.

Sphingosine-1-Phosphate Receptor 1 Proteins (S1PR1)

The protein encoded by S1PR1 is structurally similar to G protein-coupled receptors and is highly expressed in endothelial cells. Additionally we are shipping S1PR1 Antibodies (170) and S1PR1 Kits (17) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
S1PR1 1901 P21453
S1PR1 13609 O08530
Rat S1PR1 S1PR1 29733 P48303
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top S1PR1 Proteins at antibodies-online.com

Showing 4 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Wheat germ Human Un-conjugated   2 μg Log in to see 9 Days
$491.43
Details

S1PR1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

More Proteins for Sphingosine-1-Phosphate Receptor 1 (S1PR1) Interaction Partners

Human Sphingosine-1-Phosphate Receptor 1 (S1PR1) interaction partners

  1. Sphingosine 1-phosphate-induced IL-8 (show IL8 Proteins) gene expression is mainly regulated via S1PR(1), and its secretion is regulated through S1PR(2 (show S1PR2 Proteins)) receptor subtype.

  2. multiple lines of evidence demonstrate that S1PR1 signaling sets the sensitivity of pDC (show PNKD Proteins) amplification of IFN responses, thereby blunting pathogenic immune responses

  3. The results indicate that sphingosine 1-phosphate is involved in the migration of precursor T-cell lymphoblastic leukemia-lymphoma blasts in vitro, which is dependent on S1P1 expression.

  4. Overexpression of miR148a or inhibition of S1PR1 suppressed SKOV3 cell migration and invasion, while restoration of S1PR1 expression reversed the suppressive effect of miR148a upregulation on SKOV3 cell migration and invasion.

  5. the ability of ApoM (show APOM Proteins)(+)HDL (show HSD11B1 Proteins) to act as a biased agonist on S1P1 inhibits vascular inflammation, which may partially explain the cardiovascular protective functions of HDL (show HSD11B1 Proteins).

  6. S1P (show MBTPS1 Proteins) receptor modulation reduces leukocyte migration across the endothelial barrier

  7. SGPL1 (show SGPL1 Proteins) ratio correlated with increased cellular sphingosine-1-phosphate (S1P (show MBTPS1 Proteins)), and S1P (show MBTPS1 Proteins) correlated with drug resistance (IC50).

  8. Within lymphoid follicles, the S1P1 distribution pattern is complementary to that of CCR7 (show CCR7 Proteins)/CXCR4 (show CXCR4 Proteins), with strong immunoreactivity tightly restricted to mantle zone B cells. This may play a role in B-cell migration toward the S1p (show MBTPS1 Proteins)-enriched follicle center.

  9. Ponesimod, a selective S1P1 receptor modulator, causes small, dose-dependent QT prolongation.

  10. rapid reduction of endothelial cell surface expression of S1PR1 subsequent to Y143 phosphorylation is a crucial mechanism of modulating S1PR1 signaling, and hence the endothelial barrier repair function of S1P (show MBTPS1 Proteins).

Mouse (Murine) Sphingosine-1-Phosphate Receptor 1 (S1PR1) interaction partners

  1. Galphas (show GNAS Proteins) depletion blocks the S1PR1-activation induced VE-cadherin (show CDH5 Proteins) stabilization at junctions.

  2. S1P is localized in the presynaptic regions of mature neurons and is regulated by sphingosine-1-phosphate.

  3. S1P1 receptor-selective up-regulation reduces the severity of acute graft versus host disease by inhibiting macrophage recruitment.

  4. Early after VSV infection, WT and S1PR1(-/-) effector T cells localized exclusively within the lymph node paracortex. However, in contrast to WT, S1PR1(-/-) effector T cells failed to enter the sinuses.

  5. GPER and Gankyrin (show PSMD10 Proteins) might be implicated in the hormonal regulation of endometriosis and be associated with the severity of endometriosis.

  6. Sphingosine-1-Phosphate Receptor-1 Selective Agonist Enhances Collateral Growth and Protects against Subsequent Stroke.

  7. the ability of ApoM (show APOM Proteins)(+)HDL (show HSD11B1 Proteins) to act as a biased agonist on S1P1 inhibits vascular inflammation, which may partially explain the cardiovascular protective functions of HDL (show HSD11B1 Proteins).

  8. Autocrine action of S1P in DJ-1 (show PARK7 Proteins) knock-out mice vascular smooth muscle cells results from the up-regulation of SPT2 (show SPTLC2 Proteins).

  9. S1P1 had a significant effect in corneal allograft rejection inhibition.

  10. The neuronal sphingosine-1-phosphate/S1PR1/STAT3 (show STAT3 Proteins) signalling axis plays a critical role in the control of energy homeostasis.

Cow (Bovine) Sphingosine-1-Phosphate Receptor 1 (S1PR1) interaction partners

  1. Polymorphisms in promoter regions of PDHB (show PDHB Proteins), SORBS1 (show SORBS1 Proteins), and EDG1 genes showing marbling-associated expression changes.

  2. we detected 2 novel SNPs, referred to as g.1475435G>A and g.1471620G>T, in the 5' flanking region of the EDG1 between low-marbled and high-marbled steer groups

  3. EDG1 SNPs, although they may not be regarded as a causal mutation, may be useful for effective marker-assisted selection to increase the levels of marbling in Japanese Black beef cattle.

S1PR1 Protein Profile

Protein Summary

The protein encoded by this gene is structurally similar to G protein-coupled receptors and is highly expressed in endothelial cells. It binds the ligand sphingosine-1-phosphate with high affinity and high specificity, and suggested to be involved in the processes that regulate the differentiation of endothelial cells. Activation of this receptor induces cell-cell adhesion.

Gene names and symbols associated with S1PR1

  • sphingosine-1-phosphate receptor 5a (s1pr5a)
  • sphingosine-1-phosphate receptor 1 (S1PR1)
  • sphingosine-1-phosphate receptor 1 (S1pr1)
  • AI849002 protein
  • CD363 protein
  • CHEDG1 protein
  • D1S3362 protein
  • ECGF1 protein
  • EDG-1 protein
  • Edg1 protein
  • fd11a07 protein
  • Lpb1 protein
  • S1p protein
  • S1p1 protein
  • wu:fd11a07 protein
  • zgc:92296 protein

Protein level used designations for S1PR1

sphingosine-1-phosphate receptor 1 , sphingosine 1-phosphate receptor 1 , endothelial differentiation, sphingolipid G-protein-coupled receptor, 1 , S1P receptor 1 , S1P receptor Edg-1 , endothelial differentiation G-protein coupled receptor 1 , sphingosine 1-phosphate receptor EDG1 , sphingosine 1-phosphate receptor Edg-1 , endothelial differentiation sphingolipid G-protein-coupled receptor 1 , lysophospholipid receptor B1 , EDG1 (Edg1) , S1P1

GENE ID SPECIES
492350 Danio rerio
100174622 Pongo abelii
424462 Gallus gallus
457063 Pan troglodytes
490138 Canis lupus familiaris
716813 Macaca mulatta
100050049 Equus caballus
1901 Homo sapiens
13609 Mus musculus
29733 Rattus norvegicus
281135 Bos taurus
Selected quality suppliers for S1PR1 Proteins (S1PR1)
Did you look for something else?