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Sphingosine-1-Phosphate Receptor 5 Proteins (S1PR5)

The lysosphingolipid sphingosine 1-phosphate (S1P) regulates cell proliferation, apoptosis, motility, and neurite retraction. Additionally we are shipping S1PR5 Antibodies (102) and S1PR5 Kits (9) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
S1PR5 53637 Q9H228
S1PR5 94226 Q91X56
S1PR5 60399 Q9JKM5
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Top S1PR5 Proteins at antibodies-online.com

Showing 5 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Wheat germ Human Un-conjugated   2 μg Log in to see 9 Days
$491.43
Details
HOST_Escherichia coli (E. coli) Mouse Un-conjugated   5 applications Log in to see 1 to 2 Days
$312.71
Details

S1PR5 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine) ,

Rat (Rattus)

More Proteins for Sphingosine-1-Phosphate Receptor 5 (S1PR5) Interaction Partners

Human Sphingosine-1-Phosphate Receptor 5 (S1PR5) interaction partners

  1. TGF-beta2 (show TGFB2 Proteins) dependent upregulation of S1P5 is required for the induction of pro-fibrotic CTGF (show CTGF Proteins) by TGF-beta (show TGFB1 Proteins) in mesangial cells.

  2. This report is the first to demonstrate a reduction in S1P5 in multiple sclerosis lesions, which parallels that of myelin loss.

  3. Data show that sphingosine kinase SphK1 (show SPHK1 Proteins) and sphingosine-1-phosphate (S1P (show MBTPS1 Proteins)) receptors S1P1 (show S1PR1 Proteins), S1P2 (show S1PR2 Proteins), S1P3 (show S1PR3 Proteins), and S1P5 were expressed from primary, up to recurrent and secondary glioblastomas, with sphingosine kinase SphK2 (show SPHK2 Proteins) levels were highest in primary tumors.

  4. Edg-5 (show S1PR2 Proteins) receptor in brain endothelial cells contributes to optimal barrier formation and maintenance of immune quiescence of the barrier endothelium.

  5. The decreased expression level of S1PR5 on NK cells is associated with graft versus host disease occurrence after allogeneic hematopoietic stem cell transplantation.

  6. The molecular identity, functional properties, and expression profile of the S1P5 (Edg-8) receptor have been characterized.

  7. FTY720 induces time-dependent modulation of S1P (show MBTPS1 Proteins) receptors on human OPCs with consequent functional responses that are directly relevant for the remyelination process.

  8. The centrosomal sphingosine-1-phosphate receptor 5 might function as an intracellular target of sphingosine-1-phosphate linked to regulation of mitosis.

  9. Results suggest that, under serum-starved conditions, sphingosine 1-phosphate (S1P (show MBTPS1 Proteins)) further upregulates autophagic activity through S1P (show MBTPS1 Proteins)(5)-dependent pathways in PC-3 (show PCSK1 Proteins) cells.

Mouse (Murine) Sphingosine-1-Phosphate Receptor 5 (S1PR5) interaction partners

  1. Coordinated changes in CXCR4 (show CXCR4 Proteins) and S1P5 responsiveness govern NK-cell trafficking.

  2. Fndings suggest that S1P (show S1PR1 Proteins)(5) may mediate the effects of S1P (show S1PR1 Proteins) in terms of regulating ERK-1 (show MAPK3 Proteins)/2 signaling in ES cells.

  3. The molecular identity, functional properties, and expression profile of the S1P5 (Edg-8) receptor have been characterized.

  4. Edg8/S1P5 activation on oligodendroglial cells modulates two distinct functional pathways mediating either process retraction or cell survival and that these effects depend on the developmental stage of the cell.

  5. Sphingosine 1-phosphate receptors regulate chemokine (show CCL1 Proteins)-driven transendothelial migration of lymph node but not splenic T cells.

  6. KLF2 (show KLF2 Proteins) regulates T cell homeostasis at least partly by controlling CD62L (show SELL Proteins) and S1P1 (show S1PR1 Proteins) expression, and therefore T cell egress from the thymus and circulation in the periphery.

  7. These findings identify S1P5 as a T-bet-induced gene that is required for natural killer cell egress from lymph nodes and bone marrow.

S1PR5 Protein Profile

Protein Summary

The lysosphingolipid sphingosine 1-phosphate (S1P) regulates cell proliferation, apoptosis, motility, and neurite retraction. Its actions may be both intracellular as a second messenger and extracellular as a receptor ligand. S1P and the structurally related lysolipid mediator lysophosphatidic acid (LPA) signal cells through a set of G protein-coupled receptors known as EDG receptors. Some EDG receptors (e.g., EDG1\; MIM 601974) are S1P receptors\; others (e.g., EDG2\; MIM 602282) are LPA receptors.

Gene names and symbols associated with S1PR5

  • sphingosine-1-phosphate receptor 5 (s1pr5)
  • sphingosine-1-phosphate receptor 5 (S1PR5)
  • sphingosine-1-phosphate receptor 5 (S1pr5)
  • Edg-8 protein
  • Edg8 protein
  • lpB4 protein
  • S1P5 protein
  • SPPR-1 protein
  • SPPR-2 protein
  • xts1p5 protein

Protein level used designations for S1PR5

S1P receptor 5 , S1P receptor Edg-8 , endothelial differentiation G-protein-coupled receptor 8 , endothelial differentiation, sphingolipid G-protein-coupled receptor, 8 , sphingosine 1-phosphate receptor 5 , sphingosine 1-phosphate receptor EDG8 , sphingosine 1-phosphate receptor Edg-8 , Sphingosine 1-phosphate receptor Edg-8 , endothelial differentiation, sphingolipid G-protein-coupled receptor 8 , lysophospholipid receptor B4 , sphingosine-1-phosphate receptor LPB4 , NRG-1 , S1P5 , nerve growth factor-regulated G-protein-coupled receptor 1

GENE ID SPECIES
100145694 Xenopus (Silurana) tropicalis
53637 Homo sapiens
610828 Canis lupus familiaris
100141401 Sus scrofa
94226 Mus musculus
60399 Rattus norvegicus
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