Sphingosine-1-Phosphate Receptor 3 Proteins (S1PR3)

S1PR3 encodes a member of the EDG family of receptors, which are G protein-coupled receptors. Additionally we are shipping S1PR3 Antibodies (147) and S1PR3 Kits (19) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
S1PR3 1903 Q99500
S1PR3 13610 Q9Z0U9
Rat S1PR3 S1PR3 306792  
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Top S1PR3 Proteins at antibodies-online.com

Showing 4 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 50 to 55 Days
$4,244.78
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 50 to 55 Days
$6,041.49
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 11 to 12 Days
$333.33
Details
HOST_Wheat germ Human Un-conjugated   2 μg Log in to see 11 to 12 Days
$491.43
Details

S1PR3 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

More Proteins for Sphingosine-1-Phosphate Receptor 3 (S1PR3) Interaction Partners

Human Sphingosine-1-Phosphate Receptor 3 (S1PR3) interaction partners

  1. S1PR1 (show S1PR1 Proteins)/3 silencing alters proliferation, adhesion, viability and lateral motility in estrogen receptor (show ESR1 Proteins)-negative MCF-7 and estrogen receptor (show ESR1 Proteins)-positive MDA-MB-231 breast cancer cells.

  2. High S1PR3 expression is associated with increased lung adenocarcinoma.

  3. The S1P1,3 activation results in Akt (show AKT1 Proteins) phosphorylation and subsequent activation of eNOS (show NOS3 Proteins) via phosphorylation at serine(1177) and dephosphorylation at threonine(495).

  4. HDL (show HSD11B1 Proteins)-associated ApoM (show APOM Proteins) is anti-apoptotic by delivering sphingosine 1-phosphate to S1P1 (show S1PR1 Proteins) and S1P3 receptors on vascular endothelium.

  5. The study shows that S1P receptor 3 (S1PR3) mRNA is overexpressed in EBV-positive NPC (show NPC1 Proteins) patient-derived xenografts and a subset of primary NPC (show NPC1 Proteins) tissues, and that knockdown of S1PR3 suppressed the activation of AKT (show AKT1 Proteins) and the S1P (show MBTPS1 Proteins)-induced migration of NPC (show NPC1 Proteins) cells.

  6. S1pr3 promotes leukocyte rolling by mobilization of endothelial P-selectin (show SELP Proteins).

  7. Stimulation with sphingosine-1-phosphate enhances cancer stem cells via S1PR3 and subsequent Notch1 (show NOTCH1 Proteins) activation.

  8. TRPC1 (show TRPC1 Proteins) functions as a major regulator of S1P3 and VEGFR2 (show KDR Proteins) expression.

  9. Data show that sphingosine kinase SphK1 (show SPHK1 Proteins) and sphingosine-1-phosphate (S1P (show MBTPS1 Proteins)) receptors S1P1 (show S1PR1 Proteins), S1P2 (show S1PR2 Proteins), S1P3, and S1P5 (show S1PR5 Proteins) were expressed from primary, up to recurrent and secondary glioblastomas, with sphingosine kinase SphK2 (show SPHK2 Proteins) levels were highest in primary tumors.

  10. Data indicate that sphingosine 1-phosphate (S1P (show MBTPS1 Proteins)) and hepatocyte growth factor (HGF (show HGF Proteins)) induced transloaction of integrin beta4, S1P (show MBTPS1 Proteins) receptors S1PR2 (show S1PR2 Proteins) and S1PR3 to endothelial cell membrane caveolin-enriched microdomains (CEMs).

Mouse (Murine) Sphingosine-1-Phosphate Receptor 3 (S1PR3) interaction partners

  1. S1P3 deletion protects mouse soleus from age-related drop in muscle mass, force, and regenerative capacity.

  2. The finding that S1P3 receptor- and Galpha13 (show GNA13 Proteins)-mediated RhoA (show RHOA Proteins) activation is responsible for protection against ischemia/reperfusion suggests that selective targeting of S1P3 receptors could provide therapeutic benefits in ischemic heart disease.

  3. The role of the S1PR3/PDGFR-beta (show PDGFRB Proteins)/Akt (show AKT1 Proteins) pathway in sphingosine-1-phosphate -induced endothelial progenitor cells migration and angiogenesis

  4. P2RY8 promotes clustering of activated B cells within follicles in a follicular dendritic cell (FDC)-dependent manner.

  5. Smad3 (show SMAD3 Proteins) deficiency leads to mandibular condyle degradation via the sphingosine 1-phosphate (S1P (show S1PR1 Proteins))/S1P3 signaling axis

  6. S1pr3 promotes leukocyte rolling by mobilization of endothelial P-selectin (show SELP Proteins).

  7. CTGF (show CTGF Proteins) exerts profibrotic action in myoblasts via the up-regulation of sphingosine kinase-1 (show SPHK1 Proteins)/S1P3 signaling axis in TGF-beta (show TGFB1 Proteins) dependent manner.

  8. results indicate that S1P3 receptor signaling plays an important role in pulmonary inflammation and fibrosis and that this signaling occurs via CTGF (show CTGF Proteins) expression

  9. key role of Sphk1 (show SPHK1 Proteins), S1PR1 (show S1PR1 Proteins) and S1PR3 in angiogenesis underlying the liver fibrosis process

  10. Data show that two S1P (show S1PR1 Proteins) receptors, S1P2 (show S1PR2 Proteins) and S1P3, are collectively essential mediators of eyelid closure during murine development.

S1PR3 Protein Profile

Protein Summary

This gene encodes a member of the EDG family of receptors, which are G protein-coupled receptors. This protein has been identified as a functional receptor for sphingosine 1-phosphate and likely contributes to the regulation of angiogenesis and vascular endothelial cell function.

Gene names and symbols associated with S1PR3

  • sphingosine-1-phosphate receptor 3 (S1PR3)
  • sphingosine-1-phosphate receptor 3a (s1pr3a)
  • sphingosine-1-phosphate receptor 3 (S1pr3)
  • AI132464 protein
  • EDG-3 protein
  • Edg3 protein
  • Lpb3 protein
  • S1p3 protein
  • s1pr3 protein
  • si:dkeyp-31e2.1 protein

Protein level used designations for S1PR3

sphingosine-1-phosphate receptor 3 , sphingosine 1-phosphate receptor 3-like , G protein-coupled receptor, endothelial differentiation gene-3 , S1P receptor 3 , S1P receptor EDG3 , S1P receptor Edg-3 , endothelial differentiation G-protein coupled receptor 3 , endothelial differentiation, sphingolipid G-protein-coupled receptor, 3 , sphingosine 1-phosphate receptor 3 , sphingosine 1-phosphate receptor Edg-3 , S1p receptor 3 , endothelial differentiation sphingolipid G-protein-coupled receptor 3 , lysophospholipid receptor B3

GENE ID SPECIES
700903 Macaca mulatta
798390 Danio rerio
100461268 Pongo abelii
100589823 Nomascus leucogenys
1903 Homo sapiens
13610 Mus musculus
306792 Rattus norvegicus
539123 Bos taurus
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