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The lysosphingolipid sphingosine 1-phosphate (S1P) regulates cell proliferation, apoptosis, motility, and neurite retraction. Additionally we are shipping S1PR5 Kits (16) and S1PR5 Proteins (5) and many more products for this protein.
Showing 10 out of 125 products:
Bat Polyclonal S1PR5 Primary Antibody for IHC (p) - ABIN4351860
van Doorn, Lopes Pinheiro, Kooij, Lakeman, van het Hof, van der Pol, Geerts, van Horssen, van der Valk, van der Kam, Ronken, Reijerkerk, de Vries: Sphingosine 1-phosphate receptor 5 mediates the immune quiescence of the human brain endothelial barrier. in Journal of neuroinflammation 2012
Show all 2 references for 4351860
Human Polyclonal S1PR5 Primary Antibody for IF, IHC - ABIN1535594
Im, Clemens, Macdonald, Lynch: Characterization of the human and mouse sphingosine 1-phosphate receptor, S1P5 (Edg-8): structure-activity relationship of sphingosine1-phosphate receptors. in Biochemistry 2001
Human Polyclonal S1PR5 Primary Antibody for IHC, IHC (p) - ABIN4351866
Wünsche, Koch, Goldschmeding, Schwalm, Meyer Zu Heringdorf, Huwiler, Pfeilschifter: Transforming growth factor β2 (TGF-β2)-induced connective tissue growth factor (CTGF) expression requires sphingosine 1-phosphate receptor 5 (S1P5) in human mesangial cells. in Biochimica et biophysica acta 2015
Cow (Bovine) Polyclonal S1PR5 Primary Antibody for IHC, WB - ABIN2775525
Otsuki, Ota, Nishikawa, Hayashi, Suzuki, Yamamoto, Wakamatsu, Kimura, Sakamoto, Hatano, Kawai, Ishii, Saito, Kojima, Sugiyama, Ono, Okano, Yoshikawa, Aotsuka, Sasaki, Hattori, Okumura, Nagai, Sugano et al.: Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries. ... in DNA research : an international journal for rapid publication of reports on genes and genomes 2005
Human Polyclonal S1PR5 Primary Antibody for IHC (p) - ABIN4351861
Strochlic, Dwivedy, van Horck, Falk, Holt: A role for S1P signalling in axon guidance in the Xenopus visual system. in Development (Cambridge, England) 2007
Human Polyclonal S1PR5 Primary Antibody for WB - ABIN264983
Im, Heise, Ancellin, ODowd, Shei, Heavens, Rigby, Hla, Mandala, McAllister, George, Lynch: Characterization of a novel sphingosine 1-phosphate receptor, Edg-8. in The Journal of biological chemistry 2000
TGF-beta2 (show TGFB2 Antibodies) dependent upregulation of S1P5 is required for the induction of pro-fibrotic CTGF (show CTGF Antibodies) by TGF-beta (show TGFB1 Antibodies) in mesangial cells.
This report is the first to demonstrate a reduction in S1P5 in multiple sclerosis lesions, which parallels that of myelin loss.
Data show that sphingosine kinase SphK1 (show SPHK1 Antibodies) and sphingosine-1-phosphate (S1P (show MBTPS1 Antibodies)) receptors S1P1 (show S1PR1 Antibodies), S1P2 (show S1PR2 Antibodies), S1P3 (show S1PR3 Antibodies), and S1P5 were expressed from primary, up to recurrent and secondary glioblastomas, with sphingosine kinase SphK2 (show SPHK2 Antibodies) levels were highest in primary tumors.
Edg-5 (show S1PR2 Antibodies) receptor in brain endothelial cells contributes to optimal barrier formation and maintenance of immune quiescence of the barrier endothelium.
The decreased expression level of S1PR5 on NK cells is associated with graft versus host disease occurrence after allogeneic hematopoietic stem cell transplantation.
The molecular identity, functional properties, and expression profile of the S1P5 (Edg-8) receptor have been characterized.
FTY720 induces time-dependent modulation of S1P (show MBTPS1 Antibodies) receptors on human OPCs with consequent functional responses that are directly relevant for the remyelination process.
The centrosomal sphingosine-1-phosphate receptor 5 might function as an intracellular target of sphingosine-1-phosphate linked to regulation of mitosis.
Results suggest that, under serum-starved conditions, sphingosine 1-phosphate (S1P (show MBTPS1 Antibodies)) further upregulates autophagic activity through S1P (show MBTPS1 Antibodies)(5)-dependent pathways in PC-3 (show PCSK1 Antibodies) cells.
Coordinated changes in CXCR4 (show CXCR4 Antibodies) and S1P5 responsiveness govern NK-cell trafficking.
Fndings suggest that S1P (show S1PR1 Antibodies)(5) may mediate the effects of S1P (show S1PR1 Antibodies) in terms of regulating ERK-1 (show MAPK3 Antibodies)/2 signaling in ES cells.
Edg8/S1P5 activation on oligodendroglial cells modulates two distinct functional pathways mediating either process retraction or cell survival and that these effects depend on the developmental stage of the cell.
Sphingosine 1-phosphate receptors regulate chemokine (show CCL1 Antibodies)-driven transendothelial migration of lymph node but not splenic T cells.
KLF2 (show KLF2 Antibodies) regulates T cell homeostasis at least partly by controlling CD62L (show SELL Antibodies) and S1P1 (show S1PR1 Antibodies) expression, and therefore T cell egress from the thymus and circulation in the periphery.
These findings identify S1P5 as a T-bet-induced gene that is required for natural killer cell egress from lymph nodes and bone marrow.
The lysosphingolipid sphingosine 1-phosphate (S1P) regulates cell proliferation, apoptosis, motility, and neurite retraction. Its actions may be both intracellular as a second messenger and extracellular as a receptor ligand. S1P and the structurally related lysolipid mediator lysophosphatidic acid (LPA) signal cells through a set of G protein-coupled receptors known as EDG receptors. Some EDG receptors (e.g., EDG1\; MIM 601974) are S1P receptors\; others (e.g., EDG2\; MIM 602282) are LPA receptors.
S1P receptor 5
, S1P receptor Edg-8
, endothelial differentiation G-protein-coupled receptor 8
, endothelial differentiation, sphingolipid G-protein-coupled receptor, 8
, sphingosine 1-phosphate receptor 5
, sphingosine 1-phosphate receptor EDG8
, sphingosine 1-phosphate receptor Edg-8
, Sphingosine 1-phosphate receptor Edg-8
, endothelial differentiation, sphingolipid G-protein-coupled receptor 8
, lysophospholipid receptor B4
, sphingosine-1-phosphate receptor LPB4
, nerve growth factor-regulated G-protein-coupled receptor 1