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anti-Spi-B Transcription Factor (Spi-1/PU.1 Related) (SPIB) Antibodies

The protein encoded by SPIB is a transcriptional activator that binds to the PU-box (5'-GAGGAA-3') and acts as a lymphoid-specific enhancer. Additionally we are shipping SPIB Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SPIB 6689 Q01892
SPIB 272382 O35906
SPIB 499146 Q5EBA3
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Top anti-SPIB Antibodies at antibodies-online.com

Showing 10 out of 45 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Rabbit Un-conjugated WB WB Suggested Anti-SPIB Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: Daudi cell lysate WB Suggested Anti-SPIB  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.2500  Positive Control: Daudi cell lysate  SPIB is supported by BioGPS gene expression data to be expressed in Daudi 100 μL Log in to see 2 to 3 Days
$289.00
Details
Dog Rabbit Un-conjugated WB WB Suggested Anti-SPIB Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: NCI-H226 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated ICC, FACS, IHC, ELISA, WB Figure 1: Red: Control Antigen (100 ng), Purple: Antigen (10ng), Green: Antigen (50 ng), Blue: Antigen (100 ng) Figure 2: Flow cytometric analysis of NIH3T3 cells using SPIB mouse mAb (green) and negative control (red) . 100 μL Log in to see 3 to 4 Days
$430.10
Details
Human Rabbit Un-conjugated WB SPIB Antibody (C-term) (ABIN1881823) western blot analysis in MDA-MB231 cell line lysates (35 µg/lane). This demonstrates the SPIB antibody detected the SPIB protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Mouse Un-conjugated ICC, FACS, IF, IHC, ELISA, WB 100 μL Log in to see 8 to 10 Days
$551.83
Details
Dog Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit Un-conjugated WB 100 μg Log in to see 8 to 10 Days
$507.83
Details
Human Rabbit APC ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details

SPIB Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , ,
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Mouse (Murine) ,
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Rat (Rattus)


Top referenced anti-SPIB Antibodies

  1. Human Polyclonal SPIB Primary Antibody for WB - ABIN1881823 : Schmidlin, Diehl, Nagasawa, Scheeren, Schotte, Uittenbogaart, Spits, Blom: Spi-B inhibits human plasma cell differentiation by repressing BLIMP1 and XBP-1 expression. in Blood 2008 (PubMed)
    Show all 5 references for ABIN1881823

  2. Dog (Canine) Polyclonal SPIB Primary Antibody for WB - ABIN2780475 : Dontje, Schotte, Cupedo, Nagasawa, Scheeren, Gimeno, Spits, Blom: Delta-like1-induced Notch1 signaling regulates the human plasmacytoid dendritic cell versus T-cell lineage decision through control of GATA-3 and Spi-B. in Blood 2006 (PubMed)
    Show all 2 references for ABIN2780475

  3. Human Monoclonal SPIB Primary Antibody for ICC, FACS - ABIN1098113 : Marshall, Dunham, Major: Transcription factor Spi-B binds unique sequences present in the tandem repeat promoter/enhancer of JC virus and supports viral activity. in The Journal of general virology 2010 (PubMed)
    Show all 2 references for ABIN1098113

  4. Chicken Polyclonal SPIB Primary Antibody for WB - ABIN2777288 : Geng, Vedeckis: c-Myb and members of the c-Ets family of transcription factors act as molecular switches to mediate opposite steroid regulation of the human glucocorticoid receptor 1A promoter. in The Journal of biological chemistry 2005 (PubMed)

More Antibodies against SPIB Interaction Partners

Xenopus laevis Spi-B Transcription Factor (Spi-1/PU.1 Related) (SPIB) interaction partners

  1. spib is required for myeloid specification, and, in its absence, primitive myeloid cells retain hemangioblast-like characteristics and fail to migrate.

Human Spi-B Transcription Factor (Spi-1/PU.1 Related) (SPIB) interaction partners

  1. Findings establish a molecular hierarchy among POU2F2, SPIB and ID2 during B-cell differentiation, and suggest that aberrant expression of these transcription factors plays an important role in arresting plasmacytic differentiation in WM.

  2. The SRC (show SRC Antibodies) family tyrosine kinase (show TXK Antibodies) HCK (show HCK Antibodies) and the ETS (show ETS1 Antibodies) family transcription factors SPIB and EHF (show EHF Antibodies) regulate transcytosis across a human follicle-associated epithelium model.

  3. Our data indicate that the CBFbeta (show CBFB Antibodies)-SMMHC's C-terminus is essential to induce embryonic hematopoietic defects and leukemogenesis.

  4. Fine mapping identified 26 single-nucleotide polymorphisms (SNPs) across the CLEC16A (show CLEC16A Antibodies)-SOCS1 (show SOCS1 Antibodies) and 11 SNPs across the SPIB locus with significant association to primary biliary cirrhosis.

  5. Data show that in a cereblon (show CRBN Antibodies)-dependent fashion, lenalidomide downregulates IRF4 (show IRF4 Antibodies) and SPIB, transcription factors that together prevent IFNbeta production.

  6. The transcription factor Spi-B regulates human plasmacytoid dendritic cell survival through direct induction of the antiapoptotic gene BCL2 (show BCL2 Antibodies)-A1.

  7. The effect of mutating Spi-B-binding sites within the JC virus promoter/enhancer on early viral gene expression strongly suggests a role for Spi-B binding to the viral promoter/enhancer in the activation of early viral gene expression.

  8. These results suggest that Spi-B could regulate JC virus gene expression in susceptible cells, and may play an important role in JC virus activity in the immune and nervous systems.

  9. Spi-B is expressed in plasmacytoid dendritic cell precursors and inhibits T-, B-, and NK-cell development

  10. Spi-B is a key regulator of human pDC (show PNKD Antibodies) development.

Mouse (Murine) Spi-B Transcription Factor (Spi-1/PU.1 Related) (SPIB) interaction partners

  1. Our results suggest that complementary biological functions of PU.1 and Spi-B may be explained by their interaction with a similar set of regions in the genome of B cells.

  2. Nfkb1 (show NFKB1 Antibodies) transcriptional activation by PU.1 and Spi-B promotes toll (show TLR4 Antibodies)-like receptor-mediated B cell proliferation.

  3. Data show that transcription factor Spi-B-mediated negative feedback regulation limited medullary thymic epithelial cells (mTECs) development.

  4. there is a small M-cell population with developmental regulation that is Spi-B independent; however, Spi-B is probably a candidate master regulator of M-cell functional maturation and development by another pathway.

  5. Data indicate that the developmental defects of plasmacytoid dendritic cells (pDC (show PDC Antibodies)) in Spi-B-deficient mice were more prominent in the bone marrow.

  6. The Blnk (show BLNK Antibodies) promoter contains a predicted PU.1 and/or Spi-B binding site that is required for promoter activity and occupied by PU.1 and/or Spi-B.

  7. RankL (show TNFSF11 Antibodies)-induced expression of SpiB is essential for Lgr5 (show LGR5 Antibodies) stem cell-derived epithelial precursors to develop into Peyer's patch M cells

  8. Spi-B is an essential transcription factor that regulates M-cell differentiation.

  9. Regulation of follicular B cell differentiation by the related E26 transformation-specific transcription factors PU.1, Spi-B, and Spi-C (show SPIC Antibodies).

  10. DNA microarray analyses enabled us to identify two genes inhibited by v-Abl (show ABL1 Antibodies) that encode the Igk 3' enhancer-binding transcription factors Spi-B and IRF-4 (show IRF4 Antibodies).

SPIB Antigen Profile

Protein Summary

The protein encoded by this gene is a transcriptional activator that binds to the PU-box (5'-GAGGAA-3') and acts as a lymphoid-specific enhancer. Four transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with SPIB

  • Spi-B transcription factor (Spi-1/PU.1 related) (spib-a) antibody
  • Spi-B transcription factor (Spi-1/PU.1 related) (SPIB) antibody
  • Spi-B transcription factor (Spi-1/PU.1 related) (Spib) antibody
  • B42b-like antibody
  • Spi-B antibody
  • spib antibody
  • spiba antibody

Protein level used designations for SPIB

Spi-B transcription factor (Spi-1/PU.1 related) a , transcription factor Spi-B , Ets transcription factor Spi-B , Spi-1/PU.1 related

GENE ID SPECIES
379335 Xenopus laevis
6689 Homo sapiens
100688036 Canis lupus familiaris
784460 Bos taurus
272382 Mus musculus
499146 Rattus norvegicus
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