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anti-Spi-C Transcription Factor (Spi-1/PU.1 Related) (SPIC) Antibodies

Controls the development of red pulp macrophages required for red blood cells recycling and iron homeostasis. Additionally we are shipping Spi-C Transcription Factor (Spi-1/PU.1 Related) Kits (13) and Spi-C Transcription Factor (Spi-1/PU.1 Related) Proteins (6) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SPIC 97848  
SPIC 121599 Q8N5J4
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Top anti-Spi-C Transcription Factor (Spi-1/PU.1 Related) Antibodies at antibodies-online.com

Showing 10 out of 22 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Mouse Rabbit Un-conjugated WB WB Suggested Anti-SPIC Antibody Titration: 1.25ug/mlELISA Titer: 1:312500Positive Control: SP2/0 cell lysate 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from HepG2/HeLa cells, using SPIC Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Mouse Rabbit Un-conjugated WB 100 μg Log in to see 8 to 10 Days
$493.17
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Mouse Rabbit Un-conjugated ELISA, WB 100 μg Log in to see 2 to 3 Days
$343.75
Details
Human Rabbit Un-conjugated ELISA, WB 100 μL Log in to see 8 to 10 Days
$478.50
Details

SPIC Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Mouse (Murine)


Human


Top referenced anti-Spi-C Transcription Factor (Spi-1/PU.1 Related) Antibodies

  1. Cow (Bovine) Polyclonal SPIC Primary Antibody for WB - ABIN2778496 : Carlsson, Thorell, Liberg, Leanderson: SPI-C and STAT6 can cooperate to stimulate IgE germline transcription. in Biochemical and biophysical research communications 2006 (PubMed)

  2. Human Polyclonal SPIC Primary Antibody for WB - ABIN2779513 : Zhu, Schweitzer, Romer, Sulentic, DeKoter: Transgenic expression of Spi-C impairs B-cell development and function by affecting genes associated with BCR signaling. in European journal of immunology 2008 (PubMed)

  3. Human Polyclonal SPIC Primary Antibody for ELISA, WB - ABIN1534001 : Carlsson, Hjalmarsson, Liberg, Persson, Leanderson: Genomic structure of mouse SPI-C and genomic structure and expression pattern of human SPI-C. in Gene 2002 (PubMed)

  4. Mouse (Murine) Polyclonal SPIC Primary Antibody for WB - ABIN2780305 : Kosmider, Denis, Lacout, Vainchenker, Dubreuil, Moreau-Gachelin: Kit-activating mutations cooperate with Spi-1/PU.1 overexpression to promote tumorigenic progression during erythroleukemia in mice. in Cancer cell 2005 (PubMed)

More Antibodies against Spi-C Transcription Factor (Spi-1/PU.1 Related) Interaction Partners

Mouse (Murine) Spi-C Transcription Factor (Spi-1/PU.1 Related) (SPIC) interaction partners

  1. These results indicate a novel role for Spi-C as a negative regulator of B cell development and function.

  2. Study reports that Spic regulated the development of F4/80(+)VCAM1 (show VCAM1 Antibodies)(+) bone marrow macrophages (BMM) and that Spic expression in BMM and red pulp macrophages development was induced by heme, a metabolite of erythrocyte degradation.

  3. Regulation of follicular B cell differentiation by the related E26 transformation-specific transcription factors PU.1, Spi-B (show SPIB Antibodies), and Spi-C.

  4. The Kit-activating mutations cooperate with Spi-1 (show SPI1 Antibodies)/PU.1 overexpression to promote tumorigenic progression during erythroleukemia in mice.

  5. Spi-C has the potential to modulate PU.1 activity to promote B cell differentiation.

  6. data indicate that ectopic expression of Spi-C can impair B-cell development and function by affecting genes associated with BCR (show BCR Antibodies) signaling

  7. Spi-C controls development of red pulp macrophages required for red blood cell recycling and iron homeostasis

Human Spi-C Transcription Factor (Spi-1/PU.1 Related) (SPIC) interaction partners

  1. A protein interaction between SPI-C and STAT6 (show STAT6 Antibodies) is the basis for a novel mechanism for regulation of IL4 (show IL4 Antibodies) induced gene expression.

Spi-C Transcription Factor (Spi-1/PU.1 Related) (SPIC) Antigen Profile

Protein Summary

Controls the development of red pulp macrophages required for red blood cells recycling and iron homeostasis. Transcription factor that binds to the PU-box, a purine-rich DNA sequence (5'-GAGGA-3') that can act as a lymphoid-specific enhancer. Regulates VCAM1 gene expression (By similarity).

Gene names and symbols associated with SPIC

  • Spi-C transcription factor (Spi-1/PU.1 related) (LOC100349167) antibody
  • serine (or cysteine) peptidase inhibitor, clade B, member 6c (Serpinb6c) antibody
  • Spi-C transcription factor (Spi-1/PU.1 related) (SPIC) antibody
  • Spi-C transcription factor (Spi-1/PU.1 related) (Spic) antibody
  • AU019198 antibody
  • C76171 antibody
  • C76174 antibody
  • C76795 antibody
  • ovalbumin antibody
  • Prf antibody
  • Spi-C antibody
  • SPI3C antibody
  • SPIC antibody

Protein level used designations for SPIC

Spi-C transcription factor (Spi-1/PU.1 related) , serine (or cysteine) proteinase inhibitor, clade B, member 6c , serine proteinase inhibitor member 6C , transcription factor Spi-C , pu.1-related factor

GENE ID SPECIES
100349167 Oryctolagus cuniculus
97848 Mus musculus
121599 Homo sapiens
612169 Canis lupus familiaris
616438 Bos taurus
20728 Mus musculus
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