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anti-SplA/ryanodine Receptor Domain and SOCS Box Containing 1 (SPSB1) Antibodies

Probable substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity). Additionally we are shipping SPSB1 Proteins (8) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SPSB1 80176 Q96BD6
SPSB1 74646 Q9D5L7
SPSB1    
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Top anti-SPSB1 Antibodies at antibodies-online.com

Showing 7 out of 9 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB WB Suggested Anti-SPSB1 AntibodyTitration: 1.0 µg/mL  Positive Control: Fetal Lung 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB   50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Mouse Un-conjugated ELISA Detection limit for recombinant GST tagged SPSB1 is 1 ng/ml as a capture antibody. 100 μg Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated IHC, ELISA   50 μL Log in to see 9 to 11 Days
$313.50
Details
Human Mouse Un-conjugated WB Western Blot analysis of SPSB1 expression in transfected 293T cell line by SPSB1 MaxPab polyclonal antibody.Lane 1: SPSB1 transfected lysate(30.14 KDa).Lane 2: Non-transfected lysate. 50 μg Log in to see 9 Days
$430.00
Details
Human Mouse Un-conjugated ELISA   100 μg Log in to see 11 to 16 Days
$553.14
Details
Human Rabbit Un-conjugated   50 μL Log in to see 9 to 14 Days
$417.00
Details

SPSB1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human ,
,
,
Mouse (Murine)


Rat (Rattus)


More Antibodies against SPSB1 Interaction Partners

Human SplA/ryanodine Receptor Domain and SOCS Box Containing 1 (SPSB1) interaction partners

  1. SPSB1 negatively regulates the TGF-beta signaling pathway through its interaction with both endogenous and overexpressed TbetaRII (and not TbetaRI) via its Spry domain.

  2. SSB1 (show SSBP1 Antibodies)/2 is part of an ssDNA-binding heterotrimeric complex, SOSS which is involved in the maintenance of genome stability.

Mouse (Murine) SplA/ryanodine Receptor Domain and SOCS Box Containing 1 (SPSB1) interaction partners

  1. SPSB1 negatively regulates the TGF-beta signaling pathway through its interaction with both endogenous and overexpressed TbetaRII (and not TbetaRI) via its Spry domain.

  2. Collectively, these results demonstrate essential roles of Ssb1 in embryogenesis, spermatogenesis, and genome stability in vivo.

  3. These results suggest that SPSB1 acts through a negative-feedback loop that, together with SPSB2 (show SPSB2 Antibodies), controls the extent of iNOS (show NOS2 Antibodies) induction and nitric oxide production.

  4. SPSB1 and SPSB4 bind strongly to both Par-4 (show F2RL3 Antibodies) and VASA (show DDX4 Antibodies) peptides.

  5. Spsb1 is responsive to stress caused by ethanol exposure in the mouse brain, which suggests that Spsb genes have acquired different regulatory mechanisms.

SPSB1 Antigen Profile

Protein Summary

Probable substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity).

Gene names and symbols associated with SPSB1

  • splA/ryanodine receptor domain and SOCS box containing 1 (SPSB1) antibody
  • splA/ryanodine receptor domain and SOCS box containing 1 (Spsb1) antibody
  • 1110014L01Rik antibody
  • 4930422J18Rik antibody
  • AI596360 antibody
  • AI854583 antibody
  • SSB-1 antibody
  • SSB1 antibody

Protein level used designations for SPSB1

SPRY domain-containing SOCS box protein 1 , SPRY domain-containing SOCS box protein SSB-1 , novel SPRY domain containing protein , SSB-1

GENE ID SPECIES
80176 Homo sapiens
74646 Mus musculus
504407 Bos taurus
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