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SplA/ryanodine Receptor Domain and SOCS Box Containing 1 (SPSB1) ELISA Kits

Probable substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity). Additionally we are shipping SPSB1 Antibodies (9) and SPSB1 Proteins (8) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human SPSB1 SPSB1 80176 Q96BD6
Anti-Mouse SPSB1 SPSB1 74646 Q9D5L7
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More ELISA Kits for SPSB1 Interaction Partners

Human SplA/ryanodine Receptor Domain and SOCS Box Containing 1 (SPSB1) interaction partners

  1. SPSB1 negatively regulates the TGF-beta signaling pathway through its interaction with both endogenous and overexpressed TbetaRII (and not TbetaRI) via its Spry domain.

  2. SSB1 (show SSBP1 ELISA Kits)/2 is part of an ssDNA-binding heterotrimeric complex, SOSS which is involved in the maintenance of genome stability.

Mouse (Murine) SplA/ryanodine Receptor Domain and SOCS Box Containing 1 (SPSB1) interaction partners

  1. SPSB1 negatively regulates the TGF-beta signaling pathway through its interaction with both endogenous and overexpressed TbetaRII (and not TbetaRI) via its Spry domain.

  2. Collectively, these results demonstrate essential roles of Ssb1 in embryogenesis, spermatogenesis, and genome stability in vivo.

  3. These results suggest that SPSB1 acts through a negative-feedback loop that, together with SPSB2 (show SPSB2 ELISA Kits), controls the extent of iNOS (show NOS2 ELISA Kits) induction and nitric oxide production.

  4. SPSB1 and SPSB4 bind strongly to both Par-4 (show F2RL3 ELISA Kits) and VASA (show DDX4 ELISA Kits) peptides.

  5. Spsb1 is responsive to stress caused by ethanol exposure in the mouse brain, which suggests that Spsb genes have acquired different regulatory mechanisms.

SPSB1 Antigen Profile

Antigen Summary

Probable substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity).

Gene names and symbols associated with SPSB1

  • splA/ryanodine receptor domain and SOCS box containing 1 (SPSB1) antibody
  • splA/ryanodine receptor domain and SOCS box containing 1 (Spsb1) antibody
  • 1110014L01Rik antibody
  • 4930422J18Rik antibody
  • AI596360 antibody
  • AI854583 antibody
  • SSB-1 antibody
  • SSB1 antibody

Protein level used designations for SPSB1

SPRY domain-containing SOCS box protein 1 , SPRY domain-containing SOCS box protein SSB-1 , novel SPRY domain containing protein , SSB-1

GENE ID SPECIES
80176 Homo sapiens
74646 Mus musculus
504407 Bos taurus
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