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SplA/ryanodine Receptor Domain and SOCS Box Containing 2 Proteins (SPSB2)

SPSB2 encodes encodes a suppressor of cytokine signaling (SOCS) family member, and it belongs to the subfamily of proteins containing a central SPRY (repeats in splA and RyR) domain and a C-terminal SOCS box. Additionally we are shipping SplA/ryanodine Receptor Domain and SOCS Box Containing 2 Antibodies (30) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
SPSB2 84727 Q99619
SPSB2 14794 O88838
SPSB2 297592 Q5M877
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Top SplA/ryanodine Receptor Domain and SOCS Box Containing 2 Proteins at antibodies-online.com

Showing 7 out of 8 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 7 to 8 Days
$319.00
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,684.00
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 3 to 4 Days
$382.86
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

SPSB2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

Rat (Rattus)

Top referenced SplA/ryanodine Receptor Domain and SOCS Box Containing 2 Proteins

  1. Human SPSB2 Protein expressed in Escherichia coli (E. coli) - ABIN1098440 : Wang, Li, Messing, Wu: The SPRY domain-containing SOCS box protein 1 (SSB-1) interacts with MET and enhances the hepatocyte growth factor-induced Erk-Elk-1-serum response element pathway. in The Journal of biological chemistry 2005 (PubMed)

More Proteins for SplA/ryanodine Receptor Domain and SOCS Box Containing 2 (SPSB2) Interaction Partners

Human SplA/ryanodine Receptor Domain and SOCS Box Containing 2 (SPSB2) interaction partners

Mouse (Murine) SplA/ryanodine Receptor Domain and SOCS Box Containing 2 (SPSB2) interaction partners

  1. structural changes limit high-affinity interactions for SPSB2 to aspartate-containing sequences

  2. The SPRY domain-containing SOCS (show CISH Proteins) box protein SPSB2 targets iNOS (show NOS2 Proteins) for proteasomal degradation.

  3. Genetic deletion of SOCS (show CISH Proteins) Box Protein 2 results in a very mild thrombocytopenia.

  4. Determined the first SPRY-domain structure of SSB-2 that adopts a novel fold and contains conserved structural determinants for binding to prostate apoptosis response protein-4 (PAR-4 (show PAWR Proteins)).

  5. Backbone dynamics of SSB-2 by means of Modelfree analysis.

  6. The binding site on SSB-2 for the prostate apoptosis response-4 (Par-4 (show F2RL3 Proteins)) protein has been mapped in finer detail using mutational analyses.

SplA/ryanodine Receptor Domain and SOCS Box Containing 2 (SPSB2) Protein Profile

Protein Summary

This gene encodes encodes a suppressor of cytokine signaling (SOCS) family member, and it belongs to the subfamily of proteins containing a central SPRY (repeats in splA and RyR) domain and a C-terminal SOCS box. This gene is present in a gene-rich cluster on chromosome 12p13 in the vicinity of the CD4 antigen and triosephosphate isomerase genes. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with SPSB2

  • splA/ryanodine receptor domain and SOCS box containing 2 (SPSB2)
  • splA/ryanodine receptor domain and SOCS box containing 2 (Spsb2)
  • AI461677 protein
  • C9 protein
  • Grcc9 protein
  • SSB2 protein

Protein level used designations for SPSB2

SPRY domain-containing SOCS box protein 2 , SPRY domain-containing SOCS box protein SSB-2 , gene-rich cluster protein C9 , SSB-2 , gene rich cluster, C9 , gene rich cluster, C9 gene protein

GENE ID SPECIES
84727 Homo sapiens
14794 Mus musculus
297592 Rattus norvegicus
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