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Splicing Factor, Arginine/Serine Rich 7 Proteins (SFRS7)

The protein encoded by SFRS7 is a member of the serine/arginine (SR)-rich family of pre-mRNA splicing factors, which constitute part of the spliceosome. Additionally we are shipping Splicing Factor, Arginine/Serine Rich 7 Antibodies (52) and Splicing Factor, Arginine/Serine Rich 7 Kits (3) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
SFRS7 6432 Q16629
SFRS7 225027 Q8BL97
Rat SFRS7 SFRS7 362687  
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Top Splicing Factor, Arginine/Serine Rich 7 Proteins at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
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Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,594.17
Details

SFRS7 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

More Proteins for Splicing Factor, Arginine/Serine Rich 7 (SFRS7) Interaction Partners

Human Splicing Factor, Arginine/Serine Rich 7 (SFRS7) interaction partners

  1. Genome-wide identification of CD95 antigen (show FAS Proteins) alternative splicing regulators, such as SRSF7, reveals links with iron homeostasis.

  2. Coexpression of Dyrk1A (show DYRK1A Proteins) and splicing factor 9G8 leads to their translocation from the nucleus to the cytoplasm and suppresses their ability to regulate tau exon 10 splicing.

  3. Cyclic AMP-dependent protein kinase regulates 9G8-mediated alternative splicing of tau exon 10

  4. Upregulation of total tau expression (SFRS7-independent) and tau exon 10 splicing (SFRS7-dependent), as shown in this study to be both affected by STOX1A, is known to have implications in neurodegeneration.

  5. The authors report that siRNA knockdown of SRp20 or 9G8 resulted in about a 10 fold decrease in herpes simplex virus 1 yields and in nuclear accumulation of polyA+ RNA.

  6. SR proteins 9G8, SC35 (show SRSF2 Proteins), ASF/SF2 (show SRSF1 Proteins), and SRp40 (show SRSF5 Proteins) have effects on the utilization of the A1 to A5 splicing sites of HIV-1 RNA

  7. SR proteins 9G8 and ASF/SF2 (show SRSF1 Proteins) exhibit higher affinity for TAP/NXF1 (show NXF1 Proteins) when hypophosphorylated

  8. SR proteins ASF/SF2 (show SRSF1 Proteins), SC35 (show SRSF2 Proteins) and 9G8 can down-regulate the late steps of HIV-1 replication via negative impact on RNA splicing and virion production.

  9. These results indicate that 9G8 plays a key role in regulation of exon 10 splicing and imply a pathogenic role in neurodegenerative diseases.

  10. 9G8 was shown to enhance expression of unspliced RNA containing either the Mason-Pfizer monkey virus constitutive transport element

Mouse (Murine) Splicing Factor, Arginine/Serine Rich 7 (SFRS7) interaction partners

  1. 9G8 binds to an element in exon 3 and strongly enhances the excision of GnRH intron A in the presence of minimal amount of other nuclear components

Splicing Factor, Arginine/Serine Rich 7 (SFRS7) Protein Profile

Protein Summary

The protein encoded by this gene is a member of the serine/arginine (SR)-rich family of pre-mRNA splicing factors, which constitute part of the spliceosome. Each of these factors contains an RNA recognition motif (RRM) for binding RNA and an RS domain for binding other proteins. The RS domain is rich in serine and arginine residues and facilitates interaction between different SR splicing factors. In addition to being critical for mRNA splicing, the SR proteins have also been shown to be involved in mRNA export from the nucleus and in translation. Two transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with SFRS7

  • serine/arginine-rich splicing factor 7 (SRSF7)
  • serine/arginine-rich splicing factor 7 (Srsf7)
  • serine/arginine-rich splicing factor 7 (srsf7)
  • serine/arginine-rich splicing factor 7b (srsf7b)
  • 9g8 protein
  • 35kDa protein
  • 9430065L19Rik protein
  • aag3 protein
  • NX-96 protein
  • sfrs7 protein
  • srsf7 protein
  • zgc:114203 protein

Protein level used designations for SFRS7

SR splicing factor 7 , aging-associated protein 3 , splicing factor 9G8 , splicing factor, arginine/serine-rich 7, 35kDa , splicing factor, arginine/serine-rich 7 , serine/arginine-rich splicing factor 7

GENE ID SPECIES
6432 Homo sapiens
225027 Mus musculus
446584 Xenopus laevis
426265 Gallus gallus
507066 Bos taurus
362687 Rattus norvegicus
572211 Danio rerio
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