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Splicing Factor 3a, Subunit 1 Proteins (SF3A1)

SF3A1 encodes subunit 1 of the splicing factor 3a protein complex. Additionally we are shipping Splicing Factor 3a, Subunit 1 Antibodies (39) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
SF3A1 67465 Q8K4Z5
Rat SF3A1 SF3A1 305479  
SF3A1 10291 Q15459
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Top Splicing Factor 3a, Subunit 1 Proteins at antibodies-online.com

Showing 4 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

SF3A1 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human , ,
,

More Proteins for Splicing Factor 3a, Subunit 1 (SF3A1) Interaction Partners

Mouse (Murine) Splicing Factor 3a, Subunit 1 (SF3A1) interaction partners

  1. once inside the nucleus, P2X6 (show P2RX6 Proteins) subunit interacts with the splicing factor 3A1, which ultimately results in a reduction of the mRNA splicing activity

Human Splicing Factor 3a, Subunit 1 (SF3A1) interaction partners

  1. Polymorphisms in SF3A1 gene is associated with pancreatic cancer.

  2. SF3A1 polymorphisms are not associated with Colorectal Cancer Risk.

  3. show that U1-SL4 interacts with the SF3A1 protein of the U2 snRNP (show LSM2 Proteins)

  4. SF3a60 (show SF3A3 Proteins), 66, and 120, but not SF1 (show NR5A1 Proteins), are essential for pre-mRNA splicing

Splicing Factor 3a, Subunit 1 (SF3A1) Protein Profile

Protein Summary

This gene encodes subunit 1 of the splicing factor 3a protein complex. The splicing factor 3a heterotrimer includes subunits 1, 2 and 3 and is necessary for the in vitro conversion of 15S U2 snRNP into an active 17S particle that performs pre-mRNA splicing. Subunit 1 belongs to the SURP protein family\; named for the SURP (also called SWAP or Suppressor-of-White-APricot) motifs that are thought to mediate RNA binding. Subunit 1 has tandemly repeated SURP motifs in its amino-terminal half while its carboxy-terminal half contains a proline-rich region and a ubiquitin-like domain. Binding studies with truncated subunit 1 derivatives demonstrated that the two SURP motifs are necessary for binding to subunit 3 while contacts with subunit 2 may occur through sequences carboxy-terminal to the SURP motifs. Alternative splicing results in multiple transcript variants encoding different isoforms.

Gene names and symbols associated with SF3A1

  • CG16941 gene product from transcript CG16941-RA (CG16941)
  • SWAP/Surp domain-containing protein (sf3a1)
  • splicing factor 3a, subunit 1 (sf3a1)
  • splicing factor 3a, subunit 1 (spl1)
  • splicing factor 3a, subunit 1 (Sf3a1)
  • splicing factor 3a, subunit 1, 120kDa (SF3A1)
  • 1200014H24Rik protein
  • 5930416L09Rik protein
  • AI159724 protein
  • DDBDRAFT_0168938 protein
  • DDBDRAFT_0233180 protein
  • DDB_0168938 protein
  • DDB_0233180 protein
  • Dmel\\CG16941 protein
  • PRP21 protein
  • PRPF21 protein
  • SAP114 protein
  • SF3a1 protein
  • SF3A120 protein
  • si:dz150f13.2 protein
  • wu:fc38e01 protein
  • wu:fc50a11 protein
  • wu:fj37c05 protein
  • zgc:65786 protein

Protein level used designations for SF3A1

CG16941-PA , splicing factor 3a, subunit 1 , splicing factor 3A subunit 1 , ubiquitin domain-containing protein , Splicing factor 3 subunit 1 , SF3a120 , splicing factor 3 subunit 1 , splicing factor 3a, subunit 1, 120kDa , SAP 114 , pre-mRNA processing 21 , pre-mRNA splicing factor SF3a (120 kDa subunit) , spliceosome-associated protein 114

GENE ID SPECIES
42048 Drosophila melanogaster
8618597 Dictyostelium discoideum AX4
100196723 Salmo salar
9615678 Volvox carteri f. nagariensis
67465 Mus musculus
305479 Rattus norvegicus
796388 Danio rerio
10291 Homo sapiens
427717 Gallus gallus
477538 Canis lupus familiaris
504381 Bos taurus
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