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Splicing Factor 3b, Subunit 1, 155kDa (SF3B1) ELISA Kits

SF3B1 encodes subunit 1 of the splicing factor 3b protein complex. Additionally we are shipping SF3B1 Antibodies (61) and SF3B1 Proteins (3) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Mouse SF3B1 SF3B1 81898  
Anti-Rat SF3B1 SF3B1 84486  
SF3B1 23451 O75533
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Top SF3B1 ELISA Kits at antibodies-online.com

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Catalog No. Reactivity Sensitivity Range Quantity Supplier Delivery Price Details
Human 11.7 pg/ml 46.88-3000 pg/mL 96 Tests Log in to see 11 to 13 Days
$910.56
Details

More ELISA Kits for SF3B1 Interaction Partners

Zebrafish Splicing Factor 3b, Subunit 1, 155kDa (SF3B1) interaction partners

  1. Data indicate that splicing factor 3b, subunit 1 (sf3b1) mutation causes aberrant splicing of sf3b1 resulting in functional and predicted non-functional transcripts and a 90% reduction in full-length Sf3b1 protein.

Mouse (Murine) Splicing Factor 3b, Subunit 1, 155kDa (SF3B1) interaction partners

  1. myocardial hypoxia actuates fructose metabolism in human and mouse models of pathological cardiac hypertrophy through hypoxia-inducible factor 1alpha (HIF1alpha (show HIF1A ELISA Kits)) activation of SF3B1 and SF3B1-mediated splice switching of KHK (show KHK ELISA Kits)-A to KHK (show KHK ELISA Kits)-C

  2. Sf3b1 isrequired for the blastocyst formation.

  3. SF3B1 plays an important role in the regulation of hematopoietic stem cells, whereas SF3B1 haploinsufficiency itself is not associated with the myelodysplastic syndrome phenotype with ring sideroblasts.

  4. The level of Sf3b1 expression is critical for the proliferative capacity of hematopoietic stem cells. Depletion of Sf3b1 impairs proliferative capacity of hematopoietic stem cells but is not sufficient to induce myelodysplasia.

  5. SF3B1 haploinsufficiency leads to formation of ring sideroblasts in myelodysplastic syndromes.

  6. the active spliceosome, containing SAP155 phosphorylated by DYRKIA, performs pre-mRNA splicing in spermatogonia during testicular development

  7. active spliceosome, containing phosphorylated SAP155, performs pre-mRNA splicing on chromatin concomitant with transcription during testicular development.

  8. Sf3b1 and Polycomb (show CBX2 ELISA Kits) group (PcG) proteins interaction is essential for true PcG-mediated repression of Hox (show MSH2 ELISA Kits) genes.

Human Splicing Factor 3b, Subunit 1, 155kDa (SF3B1) interaction partners

  1. The finding of this study showed that an SF3B1 or EIF1AX (show EIF1AX ELISA Kits) mutation is present in a substantial subset of primary LMNs underscores that these tumors genetically resemble uveal melanoma and are different from cutaneous melanoma at the genetic level.

  2. SF3B1-mutated myelodysplastic syndrome with ring sideroblasts harbors more severe iron overload and corresponding over-erythropoiesis.

  3. studies reveal new mechanistic insight into SF3B1 as a principal player in the spliceosome and as a target of inhibitor compounds

  4. SF3B1 - novel candidate genes validated in a large case-control sample of schizophrenia.

  5. In uveal melanoma, the SF3B1(R625/K666) mutation results in deregulated splicing at a subset of junctions, mostly by the use of alternative 3'ss.

  6. Data show that tet methylcytosine dioxygenase 2 TET2 (show TET2 ELISA Kits), isocitrate dehydrogenases 1/2 IDH1 (show IDH1 ELISA Kits)/IDH2 (show IDH2 ELISA Kits), serine/arginine-rich splicing factor 2 SRSF2 (show SRSF2 ELISA Kits), splicing factor 3b subunit 1 SF3B1, and ras proteins (KRAS/NRAS) are not conserved in dog mast Cell tumors.

  7. SF3B1 mutations can propagate from hematopoietic stem cells to myeloid progeny causing myelodysplastic syndromes.

  8. Data suggest SF3B1 mutations as a biomarker that can aid in the diagnosis of patients with sideroblastic anemia (SA), allowing for the differentiation between clonal and non-clonal cases of SA.

  9. SF3B1 is associated with nucleosomes positioned over exons. SF3B1 binding of nucleosomes facilitates the splicing recognition of exons.

  10. Studying transcriptome sequencing data from chronic lymphocytic leukemia, breast cancer and uveal melanoma tumor samples, we show that hundreds of cryptic 3' splice sites (3'SSs) are used in cancers with SF3B1 mutations.

SF3B1 Antigen Profile

Antigen Summary

This gene encodes subunit 1 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. The carboxy-terminal two-thirds of subunit 1 have 22 non-identical, tandem HEAT repeats that form rod-like, helical structures. Alternative splicing results in multiple transcript variants encoding different isoforms.

Gene names and symbols associated with SF3B1

  • splicing factor 3b, subunit 1, 155kDa (SF3B1) antibody
  • splicing factor 3b, subunit 1, 155kDa (sf3b1) antibody
  • splicing factor 3b, subunit 1 (sf3b1) antibody
  • splicing factor 3b, subunit 1 (Sf3b1) antibody
  • 155kDa antibody
  • 2810001M05Rik antibody
  • AA409119 antibody
  • Hsh155 antibody
  • MDS antibody
  • PRP10 antibody
  • PRPF10 antibody
  • sap155 antibody
  • SF3B1 antibody
  • SF3b155 antibody
  • TA-8 antibody
  • Targ4 antibody
  • wu:fb99f09 antibody

Protein level used designations for SF3B1

splicing factor 3b, subunit 1, 155kDa , splicing factor 3B subunit 1 , splicing factor 3B subunit 1-like , tst , SAP 155 , pre-mRNA-splicing factor SF3b 155 kDa subunit , spliceosome-associated protein 155 , splicing factor 3b, subunit 1, 155 kDa , transforming growth factor alpha regulated gene 4 , splicing factor 3b, subunit 1, 155kD , 146 kDa nuclear protein , SF3b155 , pre-mRNA processing 10 , pre-mRNA splicing factor SF3b, 155 kDa subunit

GENE ID SPECIES
459850 Pan troglodytes
510177 Bos taurus
697773 Macaca mulatta
100022236 Monodelphis domestica
100070506 Equus caballus
100413687 Callithrix jacchus
100477819 Ailuropoda melanoleuca
100547422 Meleagris gallopavo
100559157 Anolis carolinensis
100604147 Nomascus leucogenys
446117 Danio rerio
81898 Mus musculus
84486 Rattus norvegicus
399336 Xenopus laevis
424056 Gallus gallus
23451 Homo sapiens
488456 Canis lupus familiaris
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