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SF3B3 encodes subunit 3 of the splicing factor 3b protein complex. Additionally we are shipping SF3B3 Antibodies (62) and SF3B3 Proteins (5) and many more products for this protein.
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our findings suggest a role for the elevated expression of SF3B3 in poor prognosis and tamoxifen resistance, leading to recurrence of estrogen receptor (show ESR1 ELISA Kits)-positive breast cancer
Report detection of SF3B3 gene mutations in oral cancer using high resolution melting analysis.
This gene encodes subunit 3 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. Subunit 3 has also been identified as a component of the STAGA (SPT3-TAF(II)31-GCN5L acetylase) transcription coactivator-HAT (histone acetyltransferase) complex, and the TFTC (TATA-binding-protein-free TAF(II)-containing complex). These complexes may function in chromatin modification, transcription, splicing, and DNA repair.
splicing factor 3b, subunit 3, 130kDa
, splicing factor 3b, subunit 3
, splicing factor 3B subunit 3
, SAP 130
, spliceosome-associated protein 130
, pre-mRNA-splicing factor SF3b 130 kDa subunit
, splicing factor 3B subunit 3-like
, pre-mRNA splicing factor SF3b, 130 kDa subunit