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SF3B4 encodes one of four subunits of the splicing factor 3B. Additionally we are shipping Splicing Factor 3b, Subunit 4, 49kDa Proteins (6) and many more products for this protein.
Showing 10 out of 89 products:
Human Polyclonal SF3B4 Primary Antibody for WB - ABIN1881796
Watanabe, Shionyu, Kimura, Kimata, Watanabe: Splicing factor 3b subunit 4 binds BMPR-IA and inhibits osteochondral cell differentiation. in The Journal of biological chemistry 2007
Show all 4 references for ABIN1881796
Human Polyclonal SF3B4 Primary Antibody for IHC, ELISA - ABIN1451679
Gregory, Barlow, McLay, Kaul, Swarbreck, Dunham, Scott, Howe, Woodfine, Spencer, Jones, Gillson, Searle, Zhou, Kokocinski, McDonald, Evans, Phillips, Atkinson, Cooper, Jones, Hall, Andrews, Lloyd et al.: The DNA sequence and biological annotation of human chromosome 1. ... in Nature 2006
Show all 2 references for ABIN1451679
Cow (Bovine) Polyclonal SF3B4 Primary Antibody for WB - ABIN374245
Champion-Arnaud, Reed: The prespliceosome components SAP 49 and SAP 145 interact in a complex implicated in tethering U2 snRNP to the branch site. in Genes & development 1994
Cow (Bovine) Polyclonal SF3B4 Primary Antibody for WB - ABIN2778953
Nishanian, Waldman: Interaction of the BMPR-IA tumor suppressor with a developmentally relevant splicing factor. in Biochemical and biophysical research communications 2004
High SF3B4 expression is associated with hepatocellular carcinoma.
SF3B4 haploinsufficiency confirmed as the major cause of Nager syndrome.
SF3B4 mutation is associated with Nager syndrome.
These results suggest that most cases of Nager syndrome are caused by haploinsufficiency of SF3B4.
Inhibiting the induction of two proteins involved in two of the most significantly upregulated cellular processes, ribosome biogenesis (eIF6 (show EIF6 Antibodies)) and hnRNA splicing (SF3B2 (show SF3B2 Antibodies)/SF3B4), showed that human T cells can enter the cell cycle without growing in size.
SAP49 is regulated by the BMPR-IA (show BMPR1A Antibodies) tumor suppressor
SF3b4, known to be localized in the nucleus and involved in RNA splicing, binds BMPR-IA and specifically inhibits BMP-mediated osteochondral cell differentiation
This gene encodes one of four subunits of the splicing factor 3B. The protein encoded by this gene cross-links to a region in the pre-mRNA immediately upstream of the branchpoint sequence in pre-mRNA in the prespliceosomal complex A. It also may be involved in the assembly of the B, C and E spliceosomal complexes. In addition to RNA-binding activity, this protein interacts directly and highly specifically with subunit 2 of the splicing factor 3B. This protein contains two N-terminal RNA-recognition motifs (RRMs), consistent with the observation that it binds directly to pre-mRNA.
splicing factor 3B subunit 4
, splicing factor 3b, subunit 4, 49kD
, spliceosome associated protein 49
, SAP 49
, pre-mRNA-splicing factor SF3b 49 kDa subunit
, spliceosomal protein
, spliceosome-associated protein (U2 snRNP)
, spliceosome-associated protein 49