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anti-Splicing Factor 3b, Subunit 4, 49kDa (SF3B4) Antibodies

SF3B4 encodes one of four subunits of the splicing factor 3B. Additionally we are shipping Splicing Factor 3b, Subunit 4, 49kDa Proteins (6) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SF3B4 107701 Q8QZY9
SF3B4 295270 Q6AYL5
SF3B4 10262 Q15427
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Top anti-Splicing Factor 3b, Subunit 4, 49kDa Antibodies at antibodies-online.com

Showing 10 out of 68 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-SF3B4 Antibody Titration: 0.2-1 ug/mlPositive Control: Jurkat cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated IHC, WB WB Suggested Anti-SF3B4 Antibody Titration: 1.25ug/mlPositive Control: HepG2 cell lysate 100 μL Log in to see 2 to 3 Days
$229.00
Details
Cow Goat Un-conjugated WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Goat Un-conjugated ELISA, WB ABIN184797 staining (0.1µg/ml) of Hela lysate (RIPA buffer, 35µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence. 100 μg Log in to see 4 to 5 Days
$318.20
Details
Human Rabbit Un-conjugated WB SF3B4 Antibody (Center) (ABIN1881796) western blot analysis in Hela cell line lysates (35 µg/lane). This demonstrates the SF3B4 antibody detected the SF3B4 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC, ELISA, WB   100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated IHC, WB 100 μg Log in to see 8 to 10 Days
$493.17
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated ICC, IF, WB WB Image Sample (30 ug of whole cell lysate) A: Hela 10% SDS PAGE antibody diluted at 1:1000 WB Image Sample (30 ug of whole cell lysate) A: NIH-3T3 B: JC 10% SDS PAGE antibody diluted at 1:1000 100 μL Log in to see 2 to 3 Days
$358.60
Details
Human Mouse Un-conjugated ICC, IF, IHC (p), WB Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μL Log in to see 8 to 10 Days
$451.00
Details

SF3B4 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine)
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Rat (Rattus)
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Top referenced anti-Splicing Factor 3b, Subunit 4, 49kDa Antibodies

  1. Human Polyclonal SF3B4 Primary Antibody for WB - ABIN1881796 : Watanabe, Shionyu, Kimura, Kimata, Watanabe: Splicing factor 3b subunit 4 binds BMPR-IA and inhibits osteochondral cell differentiation. in The Journal of biological chemistry 2007 (PubMed)
    Show all 4 references for ABIN1881796

  2. Human Polyclonal SF3B4 Primary Antibody for IHC, ELISA - ABIN1451679 : Gregory, Barlow, McLay, Kaul, Swarbreck, Dunham, Scott, Howe, Woodfine, Spencer, Jones, Gillson, Searle, Zhou, Kokocinski, McDonald, Evans, Phillips, Atkinson, Cooper, Jones, Hall, Andrews, Lloyd et al.: The DNA sequence and biological annotation of human chromosome 1. ... in Nature 2006 (PubMed)
    Show all 2 references for ABIN1451679

  3. Cow (Bovine) Polyclonal SF3B4 Primary Antibody for WB - ABIN374245 : Champion-Arnaud, Reed: The prespliceosome components SAP 49 and SAP 145 interact in a complex implicated in tethering U2 snRNP to the branch site. in Genes & development 1994 (PubMed)

  4. Cow (Bovine) Polyclonal SF3B4 Primary Antibody for WB - ABIN2778953 : Nishanian, Waldman: Interaction of the BMPR-IA tumor suppressor with a developmentally relevant splicing factor. in Biochemical and biophysical research communications 2004 (PubMed)

More Antibodies against Splicing Factor 3b, Subunit 4, 49kDa Interaction Partners

Human Splicing Factor 3b, Subunit 4, 49kDa (SF3B4) interaction partners

  1. High SF3B4 expression is associated with hepatocellular carcinoma.

  2. SF3B4 haploinsufficiency confirmed as the major cause of Nager syndrome.

  3. SF3B4 mutation is associated with Nager syndrome.

  4. These results suggest that most cases of Nager syndrome are caused by haploinsufficiency of SF3B4.

  5. Inhibiting the induction of two proteins involved in two of the most significantly upregulated cellular processes, ribosome biogenesis (eIF6 (show EIF6 Antibodies)) and hnRNA splicing (SF3B2 (show SF3B2 Antibodies)/SF3B4), showed that human T cells can enter the cell cycle without growing in size.

  6. SAP49 is regulated by the BMPR-IA (show BMPR1A Antibodies) tumor suppressor

  7. SF3b4, known to be localized in the nucleus and involved in RNA splicing, binds BMPR-IA and specifically inhibits BMP-mediated osteochondral cell differentiation

Splicing Factor 3b, Subunit 4, 49kDa (SF3B4) Antigen Profile

Protein Summary

This gene encodes one of four subunits of the splicing factor 3B. The protein encoded by this gene cross-links to a region in the pre-mRNA immediately upstream of the branchpoint sequence in pre-mRNA in the prespliceosomal complex A. It also may be involved in the assembly of the B, C and E spliceosomal complexes. In addition to RNA-binding activity, this protein interacts directly and highly specifically with subunit 2 of the splicing factor 3B. This protein contains two N-terminal RNA-recognition motifs (RRMs), consistent with the observation that it binds directly to pre-mRNA.

Gene names and symbols associated with SF3B4

  • Protein SAP-49 (sap-49) antibody
  • splicing factor 3b, subunit 4 (sf3b4) antibody
  • splicing factor 3b, subunit 4 (Sf3b4) antibody
  • splicing factor 3b, subunit 4, 49kDa (sf3b4) antibody
  • splicing factor 3b, subunit 4, 49kDa (SF3B4) antibody
  • 49kDa antibody
  • AFD1 antibody
  • chunp6902 antibody
  • fb36a04 antibody
  • Hsh49 antibody
  • SAP49 antibody
  • SF3b49 antibody
  • SF3b50 antibody
  • spx antibody
  • wu:fb36a04 antibody

Protein level used designations for SF3B4

splicing factor 3B subunit 4 , splicing factor 3b, subunit 4, 49kD , spliceosome associated protein 49 , SAP 49 , SF3b50 , pre-mRNA-splicing factor SF3b 49 kDa subunit , spliceosomal protein , spliceosome-associated protein (U2 snRNP) , spliceosome-associated protein 49

GENE ID SPECIES
4363023 Caenorhabditis elegans
192318 Danio rerio
107701 Mus musculus
295270 Rattus norvegicus
379792 Xenopus laevis
10262 Homo sapiens
483177 Canis lupus familiaris
506123 Bos taurus
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