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Splicing Factor 3b, Subunit 4, 49kDa (SF3B4) ELISA Kits

SF3B4 encodes one of four subunits of the splicing factor 3B. Additionally we are shipping Splicing Factor 3b, Subunit 4, 49kDa Antibodies (89) and Splicing Factor 3b, Subunit 4, 49kDa Proteins (6) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Mouse SF3B4 SF3B4 107701 Q8QZY9
Anti-Rat SF3B4 SF3B4 295270 Q6AYL5
Anti-Human SF3B4 SF3B4 10262 Q15427
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More ELISA Kits for Splicing Factor 3b, Subunit 4, 49kDa Interaction Partners

Human Splicing Factor 3b, Subunit 4, 49kDa (SF3B4) interaction partners

  1. High SF3B4 expression is associated with hepatocellular carcinoma.

  2. SF3B4 haploinsufficiency confirmed as the major cause of Nager syndrome.

  3. SF3B4 mutation is associated with Nager syndrome.

  4. These results suggest that most cases of Nager syndrome are caused by haploinsufficiency of SF3B4.

  5. Inhibiting the induction of two proteins involved in two of the most significantly upregulated cellular processes, ribosome biogenesis (eIF6 (show EIF6 ELISA Kits)) and hnRNA splicing (SF3B2/SF3B4), showed that human T cells can enter the cell cycle without growing in size.

  6. SAP49 is regulated by the BMPR-IA (show BMPR1A ELISA Kits) tumor suppressor

  7. SF3b4, known to be localized in the nucleus and involved in RNA splicing, binds BMPR-IA and specifically inhibits BMP-mediated osteochondral cell differentiation

Splicing Factor 3b, Subunit 4, 49kDa (SF3B4) Antigen Profile

Antigen Summary

This gene encodes one of four subunits of the splicing factor 3B. The protein encoded by this gene cross-links to a region in the pre-mRNA immediately upstream of the branchpoint sequence in pre-mRNA in the prespliceosomal complex A. It also may be involved in the assembly of the B, C and E spliceosomal complexes. In addition to RNA-binding activity, this protein interacts directly and highly specifically with subunit 2 of the splicing factor 3B. This protein contains two N-terminal RNA-recognition motifs (RRMs), consistent with the observation that it binds directly to pre-mRNA.

Gene names and symbols associated with SF3B4

  • Protein SAP-49 (sap-49) antibody
  • splicing factor 3b, subunit 4 (sf3b4) antibody
  • splicing factor 3b, subunit 4 (Sf3b4) antibody
  • splicing factor 3b, subunit 4, 49kDa (sf3b4) antibody
  • splicing factor 3b, subunit 4, 49kDa (SF3B4) antibody
  • 49kDa antibody
  • AFD1 antibody
  • chunp6902 antibody
  • fb36a04 antibody
  • Hsh49 antibody
  • SAP49 antibody
  • SF3b49 antibody
  • SF3b50 antibody
  • spx antibody
  • wu:fb36a04 antibody

Protein level used designations for SF3B4

splicing factor 3B subunit 4 , splicing factor 3b, subunit 4, 49kD , spliceosome associated protein 49 , SAP 49 , SF3b50 , pre-mRNA-splicing factor SF3b 49 kDa subunit , spliceosomal protein , spliceosome-associated protein (U2 snRNP) , spliceosome-associated protein 49

GENE ID SPECIES
4363023 Caenorhabditis elegans
192318 Danio rerio
107701 Mus musculus
295270 Rattus norvegicus
379792 Xenopus laevis
10262 Homo sapiens
483177 Canis lupus familiaris
506123 Bos taurus
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