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anti-Split Hand/foot Malformation (Ectrodactyly) Type 1 (SHFM1) Antibodies

The product of SHFM1 has been localized within the split hand/split foot malformation locus SHFM1 at chromosome 7. Additionally we are shipping SHFM1 Kits (5) and SHFM1 Proteins (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SHFM1 680532  
SHFM1 7979 P60896
SHFM1 20422 P60897
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Top anti-SHFM1 Antibodies at antibodies-online.com

Showing 10 out of 40 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Goat Un-conjugated ELISA, WB   100 μg Log in to see 4 to 5 Days
$318.20
Details
Human Rabbit Un-conjugated EIA, IHC (p) 50 μg Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated IHC (p), ELISA Human Skin (formalin-fixed, paraffin-embedded) stained with SHFM1 antibody ABIN214704 at 10 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μg Log in to see 8 to 10 Days
$451.00
Details
Cow Goat Un-conjugated EIA, IF   0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Mouse Rabbit Un-conjugated ELISA   100 μg Log in to see 8 to 10 Days
$405.17
Details
Human Rabbit Un-conjugated IHC, ELISA 0.05 mg Log in to see 2 to 3 Days
$481.25
Details
Human Goat Un-conjugated ELISA   100 μg Log in to see 8 to 10 Days
$595.83
Details
Human Rabbit Un-conjugated IHC (p), ELISA 50 μg Log in to see 11 to 13 Days
$541.80
Details
Human Goat Biotin ELISA   100 μL Log in to see 16 Days
$713.43
Details
Human Goat APC ELISA   100 μL Log in to see 16 Days
$713.43
Details

SHFM1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Rat (Rattus) ,
,

Human , , ,
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Mouse (Murine) , ,
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Top referenced anti-SHFM1 Antibodies

  1. Human Polyclonal SHFM1 Primary Antibody for ELISA, WB - ABIN185118 : Wei, Trempus, Cannon, Bortner, Tennant: Identification of Dss1 as a 12-O-tetradecanoylphorbol-13-acetate-responsive gene expressed in keratinocyte progenitor cells, with possible involvement in early skin tumorigenesis. in The Journal of biological chemistry 2003 (PubMed)

More Antibodies against SHFM1 Interaction Partners

Human Split Hand/foot Malformation (Ectrodactyly) Type 1 (SHFM1) interaction partners

  1. three phenotypic subregions within the SHFM1 locus link both size and genomic position of the chromosomal aberrations to the clinical variability seen in SHFM1 patients

  2. SHFM1 confers cell cycle progression and resistance to p53 (show TP53 Antibodies) stabilizing drugs in gastric cancer cells.

  3. by targeting RPA (show RPA1 Antibodies) and mimicking DNA, DSS1 functions with BRCA2 (show BRCA2 Antibodies) in a two-component homologous recombination mediator complex in genome maintenance and tumor suppression

  4. Breast cancers with high DSS1 expression have worse prognosis and shorter relapse-free survival times.

  5. Mutation screening of the SHFM1 gene in familial breast/ovarian cancer cases.

  6. DSS1 protein is critically involved in the maintenance of the transformed phenotype in cervical cancer cells, and that it might be a specific, robust and reliable marker for early detection, diagnosis and trea (show TREH Antibodies)

  7. DSS1 has a role in homologous recombinational repair in human cells

  8. p63 (show RPE65 Antibodies) binds to an enhancer element in the SHFM1 locus and this element controls expression of DLX6 and DLX5 (show DLX5 Antibodies) which are important for limb development.

  9. The DSS1 c.143G>A variant is associated with reduced DSS1 expression at RNA and protein levels and altered traffic of the DSS1 protein from the cytoplasm to the nucleus. These alterations could impair DSS1 function and may be implicated in skin cancer.

  10. 3.1 angstrom crystal structure of approximately 90-kilodalton BRCA2 domain bound to DSS1, which reveals three oligonucleotide-binding (OB) folds and a helix-turn-helix (HTH) motif

Mouse (Murine) Split Hand/foot Malformation (Ectrodactyly) Type 1 (SHFM1) interaction partners

  1. 3.1 angstrom crystal structure of approximately 90-kilodalton BRCA2 domain bound to DSS1, which reveals three oligonucleotide-binding (OB) folds and a helix-turn-helix (HTH) motif

SHFM1 Antigen Profile

Protein Summary

The product of this gene has been localized within the split hand/split foot malformation locus SHFM1 at chromosome 7. It has been proposed to be a candidate gene for the autosomal dominant form of the heterogeneous limb developmental disorder split hand/split foot malformation type 1. In addition, it has been shown to directly interact with BRCA2. It also may play a role in the completion of the cell cycle.

Gene names and symbols associated with SHFM1

  • split hand/foot malformation (ectrodactyly) type 1 (Shfm1) antibody
  • split hand/foot malformation (ectrodactyly) type 1 (SHFM1) antibody
  • DSS1 antibody
  • ECD antibody
  • SEM1 antibody
  • SHFD1 antibody
  • Shfdg1 antibody
  • Shfg antibody
  • SHSF1 antibody

Protein level used designations for SHFM1

26S proteasome complex subunit DSS1 , candidate for split hand/foot malformation type 1 , split hand/foot malformation (ectrodactyly) type 1 , 26 proteasome complex subunit DSS1 , split hand/foot malformation type 1 protein homolog , deleted in split hand/split foot protein 1 , deleted in split-hand/split-foot 1 , split hand/foot deleted protein 1 , split hand/foot malformation type 1 protein , deleted in split hand/split foot protein 1 homolog , split hand/foot deleted gene 1 , split hand/foot deleted protein 1 homolog

GENE ID SPECIES
680532 Rattus norvegicus
698349 Macaca mulatta
747549 Pan troglodytes
772237 Gallus gallus
100038817 Taeniopygia guttata
767981 Bos taurus
7979 Homo sapiens
20422 Mus musculus
608719 Canis lupus familiaris
Selected quality suppliers for anti-SHFM1 (SHFM1) Antibodies
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