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promotes cell adhesion and outgrowth of embryonic hippocampal neurons [RGD, Feb 2006].. Additionally we are shipping SPON2 Kits (22) and SPON2 Proteins (10) and many more products for this protein.
Showing 10 out of 84 products:
Human Polyclonal SPON2 Primary Antibody for ELISA, WB - ABIN4334535
Manda, Kohno, Matsuno, Takenoshita, Kuwano, Yokota: Identification of genes (SPON2 and C20orf2) differentially expressed between cancerous and noncancerous lung cells by mRNA differential display. in Genomics 1999
Cow (Bovine) Polyclonal SPON2 Primary Antibody for WB - ABIN2784890
Choy, Wang, Ogura, Lau, Rogers, Ikeo, Gojobori, Lam, Pang: Genomic annotation of 15,809 ESTs identified from pooled early gestation human eyes. in Physiological genomics 2006
Human Polyclonal SPON2 Primary Antibody for ELISA, WB - ABIN1451895
Hillier, Graves, Fulton, Fulton, Pepin, Minx, Wagner-McPherson, Layman, Wylie, Sekhon, Becker, Fewell, Delehaunty, Miner, Nash, Kremitzki, Oddy, Du, Sun, Bradshaw-Cordum, Ali, Carter, Cordes, Harris et al.: Generation and annotation of the DNA sequences of human chromosomes 2 and 4. ... in Nature 2005
SPON2 is a transcriptional target of the metastasis gene MACC1 (show MACC1 Antibodies). SPON2 induces cell motility in vitro and CRC (show CALR Antibodies) metastasis in mice. In patients, SPON2 serves as prognostic indicator for CRC (show CALR Antibodies) metastasis and survival, and might represent a promising target for therapeutic approaches.
Data suggest that spondin-2 could be an independent diagnostic and prognostic biomarker of colon cancer.
Mindin protects against vascular hyperplasia by suppression of abnormal VSMC proliferation, migration and phenotypic switching in an AKT (show AKT1 Antibodies)-dependent manner.
Using tissue microarray by immunohistostaining, we found SPON2 to be over-expressed in prostate cancer (PCa (show FLVCR1 Antibodies)). SPON2 staining was more intense in Gleason score sum 7-8 and in PCa (show FLVCR1 Antibodies) patients with metastasis.
mindin serves as a novel mediator that protects against cardiac hypertrophy and the transition to heart failure by blocking AKT (show AKT1 Antibodies)/GSK3beta (show GSK3b Antibodies) and TGF-beta1 (show TGFB1 Antibodies)-Smad (show SMAD1 Antibodies) signalling.
High Mindin is associated with diabetic nephropathy in type 2 diabetes.
Spondin 2, which is regulated by T(3), has an important role in cell invasion, cell migration, and hepatoma tumor progression.
The structure of the F-spondin (show SPON1 Antibodies) domain of mindin was determined at 1.8-A resolution.
Mindin is a novel modulator of hepatic I/R injury through regulating inflammatory responses, as well as hepatocyte apoptosis and proliferation via inactivation of the Akt (show AKT1 Antibodies) signaling pathway.
Spondin 2 regulates hepatic lipid metabolism and alleviates hepatic steatosis, obesity, inflammation, and insulin (show INS Antibodies) resistance via its interaction with PPARalpha (show PPARA Antibodies).
The data of this study demonstrated that mindin is a critical mediator of ischemic brain injury in an experimental stroke model.
Data show that mindin, as an intrinsic cardioprotective factor, prevents maladaptive remodelling and the transition to heart failure by blocking AKT (show AKT1 Antibodies)/GSK3beta (show GSK3b Antibodies) signalling.
Mindin expression is upregulated during intestinal inflammation and may induce NF-kappaBp65 promoter activation in a TLR-9 (show TLR9 Antibodies) mediated manner.
Mindin is a pattern-recognition molecule for microbial pathogens.
Mindin-integrin interactions play a key role in regulating Rho GTPase (show RACGAP1 Antibodies) expression in DCs and DC priming of T lymphocytes.
mindin plays an essential role in the host innate immune response to influenza virus infection and suggest that mindin may be used as an immune-enhancing agent in influenza infection.
mindin participates in integrin-dependent trafficking of eosinophils and can contribute to the severity of allergic airways disease.
promotes cell adhesion and outgrowth of embryonic hippocampal neurons
, differentially expressed in cancerous and non-cancerous lung cells 1