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Sprouty-Related, EVH1 Domain Containing 2 (SPRED2) ELISA Kits

SPRED2 is a member of the Sprouty (see SPRY1\; MIM 602465)/SPRED family of proteins that regulate growth factor-induced activation of the MAP kinase cascade (see MAPK1\; MIM 176948) (Nonami et al., 2004 [PubMed 15465815]).[supplied by OMIM, Mar 2008].. Additionally we are shipping SPRED2 Antibodies (22) and SPRED2 Proteins (5) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human SPRED2 SPRED2 200734 Q7Z698
Anti-Mouse SPRED2 SPRED2 114716 Q924S7
Anti-Rat SPRED2 SPRED2 305539 Q3C2P8
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More ELISA Kits for SPRED2 Interaction Partners

Human Sprouty-Related, EVH1 Domain Containing 2 (SPRED2) interaction partners

  1. Cosuppression of Sprouty and Sprouty-related negative regulators of FGF signalling in prostate cancer

  2. Spred2 was involved in erythroid differentiation of chronic myeloid leukemia (show BCL11A ELISA Kits) cells and participated in imatinib induced erythroid differentiation partly through ERK (show EPHB2 ELISA Kits) signaling.

  3. Downregulation of SPRED2 mRNA is associated with prostate cancer.

  4. Data present that galectin-1 (show LGALS1 ELISA Kits), ataxin-3 (show ATXN3 ELISA Kits) and sprouty-related EVH1 domain-containing protein 2 (SPRED2) may be associated with the progression and development of Down syndrome.

  5. Tyrosines 303/343/353 within the Sprouty-related domain of Spred2 are essential for its interaction with the p85 subunit of phosphatidylinositol 3-kinase.

  6. the knockdown of Spred2 markedly enhanced tumor growth in vivo.

  7. Sprouty and Spred proteins are negative regulators of the ERK/Elk-1 (show ELK1 ELISA Kits) pathway activation induced not only by growth-factors, but also by reactive lipidic mediators.

  8. data in the present study suggests that Spred2 is a regulator of TGF-beta1 (show TGFB1 ELISA Kits)-induced malignance in transformed keratinocytes

  9. NMR assignment of the human Spred2 EVH1 domain

  10. Spred-2 (show SPRED1 ELISA Kits) was found to be strongly expressed in glandular epithelia and, at the subcellular level, its immunoreactivity was associated with secretory vesicles. It becomes most likely that Spred-2 is involved in the regulation of secretory pathways

Mouse (Murine) Sprouty-Related, EVH1 Domain Containing 2 (SPRED2) interaction partners

  1. Cosuppression of Sprouty and Sprouty-related negative regulators of FGF signalling in prostate cancer

  2. SPREDs promote self-renewal and inhibit mesodermal differentiation of murine ES cells by selective suppression of the ERK/MAPK (show MAPK1 ELISA Kits) signaling pathway in pluripotent cells

  3. Spred-2 controls the development of lipopolysaccharide-induced lung inflammation.

  4. Spred-2 negatively regulates APAP-hepatotoxicity under the control of Kupffer cells and NK cells.

  5. Identification of SPRED2 (sprouty-related protein with EVH1 domain 2) as a negative regulator of the hypothalamic-pituitary-adrenal axis.

  6. Data show that both SPRED1 (show SPRED1 ELISA Kits) and SPRED2 inhibit the ability of DYRK1A (show DYRK1A ELISA Kits) to phosphorylate its substrates.

  7. SPRED2 is likely involved in the regulation of dynamic developmental processes.

  8. Spred-2 functions as a negative regulator of aorta-gonad-mesonephros hematopoiesis by inhibiting hematopoietic cytokine signaling.

  9. These data suggest that Spreds are key regulators of RhoA (show RHOA ELISA Kits)-mediated cell motility and signal transduction. Furthermore, our study suggests that the induction of Spreds could be a novel strategy for preventing cancer cell metastasis.

  10. Spred-1 (show SPRED1 ELISA Kits) and Spred-2 were found to be expressed predominantly in brain. It becomes most likely that Spred-2 is involved in the regulation of secretory pathways

SPRED2 Antigen Profile

Antigen Summary

SPRED2 is a member of the Sprouty (see SPRY1\; MIM 602465)/SPRED family of proteins that regulate growth factor-induced activation of the MAP kinase cascade (see MAPK1\; MIM 176948) (Nonami et al., 2004

Gene names and symbols associated with SPRED2

  • sprouty-related, EVH1 domain containing 2 (SPRED2) antibody
  • sprouty-related, EVH1 domain containing 2 (spred2) antibody
  • sprouty-related, EVH1 domain containing 2b (spred2b) antibody
  • sprouty-related, EVH1 domain containing 2 (Spred2) antibody
  • C79158 antibody
  • Spred-2 antibody
  • spred2 antibody
  • wu:fb93f08 antibody
  • Xspred2 antibody
  • Xtspred2 antibody
  • zgc:77284 antibody

Protein level used designations for SPRED2

sprouty-related, EVH1 domain containing 2 , receptor tyrosine kinase inhibitor protein , sprouty-related, EVH1 domain-containing protein 2 , fb93f08 , spred-2 , sprouty-related protein 2 with EVH-1 domain , sprouty-related, EVH1 domain-containing protein 2-like , sprouty-related protein with EVH-1 domain 2 , sprouty protein with EVH-1 domain 2, related sequence

GENE ID SPECIES
421271 Gallus gallus
481397 Canis lupus familiaris
496441 Xenopus (Silurana) tropicalis
519081 Bos taurus
697196 Macaca mulatta
793290 Danio rerio
100062947 Equus caballus
100174296 Pongo abelii
100466726 Ailuropoda melanoleuca
100518067 Sus scrofa
459284 Pan troglodytes
100391761 Callithrix jacchus
100562862 Anolis carolinensis
100588144 Nomascus leucogenys
200734 Homo sapiens
114716 Mus musculus
305539 Rattus norvegicus
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