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Src Kinase Associated Phosphoprotein 2 (SKAP2) ELISA Kits

The protein encoded by SKAP2 belongs to the src family kinases. Additionally we are shipping SKAP2 Antibodies (65) and SKAP2 Proteins (12) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Mouse SKAP2 SKAP2 54353 Q3UND0
Anti-Human SKAP2 SKAP2 8935 O75563
Anti-Rat SKAP2 SKAP2 155183 Q920G0
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More ELISA Kits for SKAP2 Interaction Partners

Mouse (Murine) Src Kinase Associated Phosphoprotein 2 (SKAP2) interaction partners

  1. Macrophages assemble the appropriate motile machinery to infiltrate tumors and promote disease progression, and implicate SKAP2 as an attractive candidate for therapeutically targeting TAMs.

  2. RA70/Scap2 may be necessary for RA-induced neuronal differentiation from the posterior neuroectoderm.

  3. a novel role of SKAP-Hom and its phosphorylation in the regulation of cellular motility.

  4. integrin activation by the ADAP (show APP ELISA Kits)-SKAP55 (show SKAP1 ELISA Kits)-signaling module controls the stability and duration of T cell-dendritic cell contacts during the progressive phases necessary for optimal T cell activation.

  5. Sirpalpha is not exclusively immunoinhibitory, and illuminate previously unexplained observations implicating Skap2 and Sirpalpha in mouse models of inflammatory disease.

  6. These results revealed an essential role for HSF4-mediated SKAP2 expression in the regulation of actin reorganization during lens differentiation.

  7. M-CSF receptor induces tyrosine phosphorylation of SKAP55R adaptor and its association with actin

  8. SKAP-HOM is required for proper activation of the immune system, likely by regulating the cross-talk between immunoreceptors and integrins.

  9. A signaling module comprising the cytosolic adapter proteins ADAP (show APP ELISA Kits) and SKAP55 (show SKAP1 ELISA Kits) is involved in TCR-mediated inside-out signaling and, the interaction between ADAP (show APP ELISA Kits) and SKAP55 (show SKAP1 ELISA Kits) is mandatory for integrin activation.

  10. Results describe a link between ADAP (show APP ELISA Kits)/SKAP-55 (show SKAP1 ELISA Kits) and the Rap1 (show TERF2IP ELISA Kits)/RIAM (show APBB1IP ELISA Kits) complex and provide a potential new mechanism for T cell receptor-mediated integrin activation.

Human Src Kinase Associated Phosphoprotein 2 (SKAP2) interaction partners

  1. Macrophages assemble the appropriate motile machinery to infiltrate tumors and promote disease progression, and implicate SKAP2 as an attractive candidate for therapeutically targeting TAMs.

  2. Skap2 is necessary for macrophage migration, chemotaxis, global actin reorganization and local actin reorganization upon integrin engagement.

  3. SKAP2 expression levels in NSCLC tissues could be a powerful biomarker of poor prognosis. Therefore, SKAP2 is a promising candidate molecular target for Non-small cell lung cancer treatment.

  4. results suggest that SKAP2 negatively regulates cell migration and tumor invasion in fibroblasts and glioblastoma cells by suppressing actin assembly induced by the WAVE2 (show WASF2 ELISA Kits)-cortactin (show CTTN ELISA Kits) complex

  5. analysis of substrate specificity of lymphoid-specific tyrosine phosphatase (Lyp (show PTPN22 ELISA Kits)) and identification of Src kinase (show CSK ELISA Kits)-associated protein of 55 kDa homolog (SKAP-HOM) as a Lyp (show PTPN22 ELISA Kits) substrate

  6. cloning & characterization of an adaptor protein that functions as a downstream target for RAFTK (show PTK2B ELISA Kits) & plays a role in alpha-synuclein (show SNCA ELISA Kits) phosphorylation

  7. studies provide insights into the molecular mechanism ofrelated adhesion focal tyrosine kinase (show TXK ELISA Kits) (RAFTK (show PTK2B ELISA Kits)) autophosphorylation and the specific role of Src (show SRC ELISA Kits) in the regulation of RAFTK (show PTK2B ELISA Kits) activation

  8. Overexpression of SKAP2 is associated with the development of pancreatic ductal adenocarcinoma

SKAP2 Antigen Profile

Antigen Summary

The protein encoded by this gene belongs to the src family kinases. This protein is similar to the src kinase associated phosphoprotein 1. It is an adaptor protein that is thought to play an essential role in the src signaling pathway in various cells. It inhibits PTK2B/RAFTK activity and regulates alpha-synuclein phosphorylation.

Gene names and symbols associated with SKAP2

  • src kinase associated phosphoprotein 2 (skap2-b) antibody
  • SRC kinase associated phosphoprotein 2 (CCC13826_0176) antibody
  • src family associated phosphoprotein 2 (Skap2) antibody
  • src kinase associated phosphoprotein 2 (SKAP2) antibody
  • src kinase associated phosphoprotein 2 (Skap2) antibody
  • src kinase associated phosphoprotein 2 (skap2) antibody
  • 2610021A10Rik antibody
  • AA960083 antibody
  • BB137539 antibody
  • mSKAP55R antibody
  • PRAP antibody
  • RA70 antibody
  • SAPS antibody
  • SCAP2 antibody
  • Scap55r antibody
  • si:dz31b14.4 antibody
  • si:dz227h09.6 antibody
  • SKAP-HOM antibody
  • SKAP55 antibody
  • SKAP55R antibody
  • zgc:65975 antibody
  • zgc:158223 antibody

Protein level used designations for SKAP2

src kinase-associated phosphoprotein 2-B , SRC kinase associated phosphoprotein 2 , SKAP55 homolog , SKAP55 homologue , Src-associated adaptor protein , pyk2/RAFTK-associated protein , src family-associated phosphoprotein 2 , src kinase-associated phosphoprotein 2 , src kinase-associated phosphoprotein 55-related protein , src-associated adapter protein with PH and SH3 domains , Fyn-associated phosphoprotein SKAP55 homologue , Pyk2/RAFTK-associated protein , SKAP-55HOM , retinoic acid-induced protein 70 , src family associated phosphoprotein 2 , src kinase-associated phosphoprotein of 55-related protein , src-associated adaptor protein , SKAP-HOM , SKAP55-HOM , Src kinase-associated phosphoprotein 2

GENE ID SPECIES
495326 Xenopus laevis
5596751 Campylobacter concisus 13826
54353 Mus musculus
8935 Homo sapiens
482366 Canis lupus familiaris
616545 Bos taurus
155183 Rattus norvegicus
100171875 Pongo abelii
368564 Danio rerio
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