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Src Kinase Associated Phosphoprotein 2 Proteins (SKAP2)

The protein encoded by SKAP2 belongs to the src family kinases. Additionally we are shipping SKAP2 Antibodies (67) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
SKAP2 54353 Q3UND0
SKAP2 8935 O75563
SKAP2 155183 Q920G0
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Top SKAP2 Proteins at antibodies-online.com

Showing 10 out of 12 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 11 to 12 Days
$246.96
Details
Yeast Xenopus tropicalis His tag   1 mg Log in to see 56 to 66 Days
$2,883.83
Details
Yeast Takifugu rubripes His tag   1 mg Log in to see 56 to 66 Days
$2,887.50
Details
Yeast Zebrafish His tag   1 mg Log in to see 56 to 66 Days
$2,924.17
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,977.33
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,977.33
Details
Yeast Pongo abelii His tag   1 mg Log in to see 56 to 66 Days
$2,979.17
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

SKAP2 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human , ,
,
Rat (Rattus)

More Proteins for Src Kinase Associated Phosphoprotein 2 (SKAP2) Interaction Partners

Mouse (Murine) Src Kinase Associated Phosphoprotein 2 (SKAP2) interaction partners

  1. Macrophages assemble the appropriate motile machinery to infiltrate tumors and promote disease progression, and implicate SKAP2 as an attractive candidate for therapeutically targeting TAMs.

  2. RA70/Scap2 may be necessary for RA-induced neuronal differentiation from the posterior neuroectoderm.

  3. a novel role of SKAP-Hom and its phosphorylation in the regulation of cellular motility.

  4. integrin activation by the ADAP (show APP Proteins)-SKAP55 (show SKAP1 Proteins)-signaling module controls the stability and duration of T cell-dendritic cell contacts during the progressive phases necessary for optimal T cell activation.

  5. Sirpalpha is not exclusively immunoinhibitory, and illuminate previously unexplained observations implicating Skap2 and Sirpalpha in mouse models of inflammatory disease.

  6. These results revealed an essential role for HSF4-mediated SKAP2 expression in the regulation of actin reorganization during lens differentiation.

  7. M-CSF receptor induces tyrosine phosphorylation of SKAP55R adaptor and its association with actin

  8. SKAP-HOM is required for proper activation of the immune system, likely by regulating the cross-talk between immunoreceptors and integrins.

  9. A signaling module comprising the cytosolic adapter proteins ADAP (show APP Proteins) and SKAP55 (show SKAP1 Proteins) is involved in TCR-mediated inside-out signaling and, the interaction between ADAP (show APP Proteins) and SKAP55 (show SKAP1 Proteins) is mandatory for integrin activation.

  10. Results describe a link between ADAP (show APP Proteins)/SKAP-55 (show SKAP1 Proteins) and the Rap1 (show TERF2IP Proteins)/RIAM (show APBB1IP Proteins) complex and provide a potential new mechanism for T cell receptor-mediated integrin activation.

Human Src Kinase Associated Phosphoprotein 2 (SKAP2) interaction partners

  1. Macrophages assemble the appropriate motile machinery to infiltrate tumors and promote disease progression, and implicate SKAP2 as an attractive candidate for therapeutically targeting TAMs.

  2. Skap2 is necessary for macrophage migration, chemotaxis, global actin reorganization and local actin reorganization upon integrin engagement.

  3. SKAP2 expression levels in NSCLC tissues could be a powerful biomarker of poor prognosis. Therefore, SKAP2 is a promising candidate molecular target for Non-small cell lung cancer treatment.

  4. results suggest that SKAP2 negatively regulates cell migration and tumor invasion in fibroblasts and glioblastoma cells by suppressing actin assembly induced by the WAVE2 (show WASF2 Proteins)-cortactin (show CTTN Proteins) complex

  5. analysis of substrate specificity of lymphoid-specific tyrosine phosphatase (Lyp (show PTPN22 Proteins)) and identification of Src kinase (show CSK Proteins)-associated protein of 55 kDa homolog (SKAP-HOM) as a Lyp (show PTPN22 Proteins) substrate

  6. cloning & characterization of an adaptor protein that functions as a downstream target for RAFTK & plays a role in alpha-synuclein phosphorylation

  7. studies provide insights into the molecular mechanism ofrelated adhesion focal tyrosine kinase (show TXK Proteins) (RAFTK (show PTK2B Proteins)) autophosphorylation and the specific role of Src (show SRC Proteins) in the regulation of RAFTK (show PTK2B Proteins) activation

  8. Overexpression of SKAP2 is associated with the development of pancreatic ductal adenocarcinoma

SKAP2 Protein Profile

Protein Summary

The protein encoded by this gene belongs to the src family kinases. This protein is similar to the src kinase associated phosphoprotein 1. It is an adaptor protein that is thought to play an essential role in the src signaling pathway in various cells. It inhibits PTK2B/RAFTK activity and regulates alpha-synuclein phosphorylation.

Gene names and symbols associated with SKAP2

  • src kinase associated phosphoprotein 2 (skap2-b)
  • SRC kinase associated phosphoprotein 2 (CCC13826_0176)
  • src family associated phosphoprotein 2 (Skap2)
  • src kinase associated phosphoprotein 2 (SKAP2)
  • src kinase associated phosphoprotein 2 (Skap2)
  • src kinase associated phosphoprotein 2 (skap2)
  • 2610021A10Rik protein
  • AA960083 protein
  • BB137539 protein
  • mSKAP55R protein
  • PRAP protein
  • RA70 protein
  • SAPS protein
  • SCAP2 protein
  • Scap55r protein
  • si:dz31b14.4 protein
  • si:dz227h09.6 protein
  • SKAP-HOM protein
  • SKAP55 protein
  • SKAP55R protein
  • zgc:65975 protein
  • zgc:158223 protein

Protein level used designations for SKAP2

src kinase-associated phosphoprotein 2-B , SRC kinase associated phosphoprotein 2 , SKAP55 homolog , SKAP55 homologue , Src-associated adaptor protein , pyk2/RAFTK-associated protein , src family-associated phosphoprotein 2 , src kinase-associated phosphoprotein 2 , src kinase-associated phosphoprotein 55-related protein , src-associated adapter protein with PH and SH3 domains , Fyn-associated phosphoprotein SKAP55 homologue , Pyk2/RAFTK-associated protein , SKAP-55HOM , retinoic acid-induced protein 70 , src family associated phosphoprotein 2 , src kinase-associated phosphoprotein of 55-related protein , src-associated adaptor protein , SKAP-HOM , SKAP55-HOM , Src kinase-associated phosphoprotein 2

GENE ID SPECIES
495326 Xenopus laevis
5596751 Campylobacter concisus 13826
54353 Mus musculus
8935 Homo sapiens
482366 Canis lupus familiaris
616545 Bos taurus
155183 Rattus norvegicus
100171875 Pongo abelii
368564 Danio rerio
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