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Stearoyl-CoA desaturase (SCD\; EC 188.8.131.52) is an integral membrane protein of the endoplasmic reticulum that catalyzes the formation of monounsaturated fatty acids from saturated fatty acids. Additionally we are shipping Stearoyl-CoA Desaturase 5 Kits (2) and and many more products for this protein.
Showing 10 out of 23 products:
Human Polyclonal SCD5 Primary Antibody for WB - ABIN656967
Jugessur, Shi, Gjessing, Lie, Wilcox, Weinberg, Christensen, Boyles, Daack-Hirsch, Nguyen, Christiansen, Lidral, Murray: Maternal genes and facial clefts in offspring: a comprehensive search for genetic associations in two population-based cleft studies from Scandinavia. in PLoS ONE 2010
Human Polyclonal SCD5 Primary Antibody for EIA, WB - ABIN954682
Komura, Uchiba, Mizuochi, Arai, Harada, Katsuya, Okajima: Antithrombin inhibits lipopolysaccharide-induced tumor necrosis factor-alpha production by monocytes in vitro through inhibition of Egr-1 expression. in Journal of thrombosis and haemostasis : JTH 2008
SCD5 appears to functionally connect tumour cells and the surrounding stroma toward modification of the tumour microenvironment, with consequences on tumour spread and resistance to treatment.
The protective effect of TO901317 was lost after gene silencing of Scd-1 (show SCD Antibodies)/-2, thereby confirming that the protective effect of TO901317 is mediated by Scd-1 (show SCD Antibodies)/-2.
Data suggest that, by a coordinated modulation of key lipogenic pathways and transduction signaling cascades, SCD5 participates in the regulation of neuronal cell growth and differentiation.
SCD4 demonstrates tissue-specific regulation by leptin (show LEP Antibodies) and dietary factors
The identification and characterization of SCD2, and its relationship to human SCD1 and mouse SCD2, are reported.
In this paper, we describe for the first time a second SCD (show SCD Antibodies) isoform in cattle, which appears to be an ortholog of human SCD5 rather than a homolog of bovine SCD1 (show SCD Antibodies) or any of the described murine SCD (show SCD Antibodies) isoforms
This is the first study examining a potential role for SCD5 in providing 18:1n-9 for brain lipids.
This is the first report of potential regulators of SCD5 transcription.
Stearoyl-CoA desaturase (SCD\; EC 184.108.40.206) is an integral membrane protein of the endoplasmic reticulum that catalyzes the formation of monounsaturated fatty acids from saturated fatty acids. SCD may be a key regulator of energy metabolism with a role in obesity and dislipidemia. Four SCD isoforms, Scd1 through Scd4, have been identified in mouse. In contrast, only 2 SCD isoforms, SCD1 (MIM 604031) and SCD5, have been identified in human. SCD1 shares about 85% amino acid identity with all 4 mouse SCD isoforms, as well as with rat Scd1 and Scd2. In contrast, SCD5 shares limited homology with the rodent SCDs and appears to be unique to primates (Wang et al., 2005
, stearoyl-CoA 9-desaturase
, stearoyl-CoA desaturase 4