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anti-Stearoyl-CoA Desaturase (Delta-9-Desaturase) (SCD) Antibodies

SCD encodes an enzyme involved in fatty acid biosynthesis, primarily the synthesis of oleic acid. Additionally we are shipping Stearoyl-CoA Desaturase (Delta-9-Desaturase) Kits (26) and Stearoyl-CoA Desaturase (Delta-9-Desaturase) Proteins (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SCD 6319 O00767
SCD 83792 Q6P7B9
SCD 20249 P13516
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Top anti-Stearoyl-CoA Desaturase (Delta-9-Desaturase) Antibodies at

Showing 10 out of 87 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated IHC, WB WB Suggested Anti-SCD  Antibody Titration: 1.0 µg/mL  Positive Control: Human Liver 100 μL Log in to see 2 to 3 Days
Human Goat Un-conjugated EIA, IHC (p) AP22447PU-N SCD antibody staining of Paraffin Embedded Human Liver at 5 µg/ml. Steamed antigen retrieval with citrate buffer pH 6, AP-staining. 0.1 mg Log in to see 6 to 8 Days
Human Goat Un-conjugated ELISA, FACS, IHC, IHC (p) Flow Cytometry: SCD Antibody [ABIN250924] - staining of HepG2 cells mixed in with PBL. Detected by fluorescence with PE for SCD in green and with OC515 for CD45 (CYT-450C) in red. Immunohistochemistry-Paraffin: SCD Antibody [ABIN250924] - (5ug/ml) staining Human Liver. Steamed antigen retrieval with citrate buffer pH 6, AP-staining. 0.1 mg Log in to see 7 to 9 Days
Hamster Rabbit Un-conjugated WB 100 μg Log in to see 2 to 3 Days
Human Goat Un-conjugated IHC, ELISA, WB   100 μg Log in to see 4 to 5 Days
Human Goat Un-conjugated IHC (p), ELISA Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 7 to 9 Days
Human Rabbit Un-conjugated WB Western blot analysis of SCD expression in HeLa (A), NS-1 (B), PC12 (C) whole cell lysates. 200 μL Log in to see 9 Days
Goat Rabbit Un-conjugated IHC (p), WB 100 μg Log in to see 7 to 9 Days
Human Rabbit Un-conjugated IHC, ELISA, WB 100 μg Log in to see 2 to 3 Days
Human Rabbit Un-conjugated ICC, IF, WB Immunocytochemistry/Immunofluorescence: SCD Antibody [NBP1-26393] - SCD staining in Hela cells detected with a Dylight 488 labeled secondary antibody (Green) with Hoechst 33258 nuclear counterstain (Blue). 0.1 mL Log in to see 7 to 9 Days

SCD Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Stearoyl-CoA Desaturase (Delta-9-Desaturase) Antibodies

  1. Cow (Bovine) Polyclonal SCD Primary Antibody for IHC, WB - ABIN2777599 : Cohen, Ntambi, Friedman: Stearoyl-CoA desaturase-1 and the metabolic syndrome. in Current drug targets. Immune, endocrine and metabolic disorders 2003 (PubMed)

  2. Human Polyclonal SCD Primary Antibody for ELISA, FACS - ABIN250924 : Zhang, Yang, Shi: Characterization of human SCD2, an oligomeric desaturase with improved stability and enzyme activity by cross-linking in intact cells. in The Biochemical journal 2005 (PubMed)

More Antibodies against Stearoyl-CoA Desaturase (Delta-9-Desaturase) Interaction Partners

Zebrafish Stearoyl-CoA Desaturase (Delta-9-Desaturase) (SCD) interaction partners

  1. whole-mount in situ hybridization and real-time quantitative RT-PCR to identify expression of the zebrafish SCD gene at five different stages of development

Human Stearoyl-CoA Desaturase (Delta-9-Desaturase) (SCD) interaction partners

  1. A relevant link between one-night sleep deprivation , hepatic SCD1 expression and de-novo fatty acid synthesis via epigenetically driven regulatory mechanisms was found.

  2. stearoyl-coenzyme A desaturase 1 has a role in clear cell renal cell carcinoma (show MOK Antibodies)

  3. Chronic exposure to chewing tobacco induces carcinogenesis in non-malignant oral epithelial cells and SCD plays an essential role in this process.

  4. This study illustrates for the first time that, in contrast to hepatic and adipose tissue, estrogen induces SCD-1 expression and activity in breast carcinoma cells. These results support SCD-1 as a therapeutic target in estrogen-sensitive breast cancer.

  5. The data indicate a direct inhibitory interaction of polyunsaturated fatty acids with LXRalpha (show NR1H3 Antibodies), a consequent reduction of SREBP-1 (show SREBF1 Antibodies) and of its binding to SCD1 promoter.

  6. Both siRNA-mediated and pharmacological inhibition of SCD1 impaired tumor cells migration.

  7. SCD1 is found upregulated upon renal cell transformation indicating that its activity, while not impacting proliferation, represents a critical bottleneck for tumourigenesis

  8. SCD1 negatively regulates autophagy-induced cell death in human hepatocellular carcinoma through inactivation of the AMPK (show PRKAA1 Antibodies) signaling pathway.

  9. An association with Graves ophthalmopathy was shown for SNP rs1393491 in SCD.

  10. Stearoyl-CoA desaturase is encoded by an SCD gene, which, depending on the species, may exist as different isoforms. (review)

Cow (Bovine) Stearoyl-CoA Desaturase (Delta-9-Desaturase) (SCD) interaction partners

  1. Here, the association between DGAT1 (show DGAT1 Antibodies) K232A, SCD1 A293V, and LEPR (show LEPR Antibodies) T945M markers with milk fat composition in southern Chile was evaluated. The most frequent variants for DGAT1 (show DGAT1 Antibodies), SCD1, and LEPR (show LEPR Antibodies) polymorphisms were GC/GC (show GC Antibodies), C, and C, respectively. The SCD1 CC genotype was associated with a low cholesterolemic FA content, a high ratio of linolenic acid to cholesterolemic FA, and lower conjugated-linolenic acid and PUFA content.

  2. significant effects of the SCD gene on milk medium- and long-chain unsaturated fatty acids, especially for C14 (show LGALS1 Antibodies):1 and C14 (show LGALS1 Antibodies) index in dairy cattle

  3. Studied the responsiveness of bovine SCD1 promoter to serum, insulin (show INS Antibodies), oleic acid, and NFY transcription factor in BME-UV1 cells.

  4. The results suggest that a mutation of SCD1, but not LEPR (show LEPR Antibodies) or ABCG2 (show ABCG2 Antibodies), might be useful as a DNA marker to decrease reproductive problems and improve production traits in Iranian Holstein dairy cows.

  5. Suppression of CPT1B (show CPT1B Antibodies) and induction of SCD and CEBPB (show CEBPB Antibodies) by supplemental arginine promotes increased adiposity in Angus steers.

  6. This study showed that milk somatic cells can be used as a source of mRNA to study SCD1 expression in dairy cows, offering a non-invasive alternative to mammary tissue samples obtained by biopsy.

  7. This study presents evidence that there are breed- and diet-induced variations on lipid metabolism in the muscle, which may be, at least partially, modulated by the stearoyl-CoA desaturase (SCD) gene expression levels.

  8. These results provide detailed genetic information for the SREBP1 (show SREBF1 Antibodies) signalling pathway and SCD that can be used to change milk fat composition by marker-assisted breeding.

  9. study evaluated the contributions of polymorphisms of FASN (show FASN Antibodies) and SCD genes on fatty acid composition in muscle in two different populations: 1189 and 1058 Japanese Black cattle from the Miyagi and the Yamagata populations

  10. Results suggest that SCD and FASN (show FASN Antibodies) are strong candidate genes influencing fatty acid composition in beef cattle.

Pig (Porcine) Stearoyl-CoA Desaturase (Delta-9-Desaturase) (SCD) interaction partners

  1. genetic association study in Duroc gilts/barrows in Spain: Data suggest that T allele in promoter region of SCD (2228T>C) leads to up-regulation of monounsaturated fatty acid content of biceps femoris/ham (show ATF7IP Antibodies) which is maintained in dry-cured ham (show ATF7IP Antibodies).

  2. The study provides evidence that there exists genetic variation in the SCD gene with the potential to increase monounsaturated content in pork.

  3. There was a positive relationship between stearoyl-CoA desaturase (SCD) protein expression in longissimus muscle and monounsaturated fatty acid content, and SCD protein expression and total muscle fatty acid content in Large White x Landrace breeds.

  4. The relationships between a point mutation of SCD and multiple production traits in swine are reported.

  5. The results indicate that the haplotype of the SCD gene has a strong effect on fatty acid composition and melting point of fat.

  6. Stearoyl-CoA desaturase(SCD) has a total of 21 gene polymorphisms in the 21-kb DNA sequence, adn (show CFD Antibodies) RT-PCR result indicates that the SCD gene is expressed ubiquitously in tissues.

Mouse (Murine) Stearoyl-CoA Desaturase (Delta-9-Desaturase) (SCD) interaction partners

  1. Scd1 protects cells against lipotoxicity-mediated apoptosis in proximal tubular cells.

  2. Scd1 Is Regulated by Dbc1 (show DBC1 Antibodies) and SirT1 (show SIRT1 Antibodies).

  3. Study provides new insights into the critical role of SCD1 as a regulator of adipocyte function and lipid metabolism.

  4. The study reports report the 3.25-A crystal structure of human SCD1 in complex with its substrate, stearoyl-coenzyme A, which defines the new SCD1 dimetal catalytic center and reveals the determinants of substrate binding.

  5. SCD1 is a novel oncogenic factor specifically required for tumor cell viability in anaplastic thyroid carcinoma.

  6. crystal structure of mouse SCD1 bound to stearoyl-CoA at 2.6 A resolution

  7. Data indicate that lowering stearoyl-CoA desaturase-1 (SCD-1) activity specifically activates p38 mitogen-activated protein kinase (show MAPK14 Antibodies) (P38MAPK (show MAPK14 Antibodies)).

  8. Results provide new mechanistic insight into the role of SCD1 as a regulator of fatty acid profiles and Triacylglycerol (TG) synthesis in adipocytes, and reinforce that modulating SCD1 activity may help reduce the risk of obesity-related complications.

  9. Data indicate that global DNA methylation (show HELLS Antibodies) level in adipocytes depends on stearoyl-CoA desaturase 1 (SCD1) expression/activity.

  10. Results show that SCD1 was expressed selectively in the S3 segment of proximal tubule cells, and SCD1 abundance was increased in uromodulin (show UMOD Antibodies)-associated kidney disease affected kidneys.

Arabidopsis thaliana Stearoyl-CoA Desaturase (Delta-9-Desaturase) (SCD) interaction partners

  1. SCD1 and SCD2 function in clathrin-mediated membrane trafficking essential to both cytokinesis and cell expansion.

Stearoyl-CoA Desaturase (Delta-9-Desaturase) (SCD) Antigen Profile

Protein Summary

This gene encodes an enzyme involved in fatty acid biosynthesis, primarily the synthesis of oleic acid. Transcripts of approximately 3.9 and 5.2 kb, differing only by alternative polyadenlyation signals, have been detected. A gene encoding a similar enzyme is located on chromosome 4 and a pseudogene of this gene is located on chromosome 17.

Gene names and symbols associated with SCD

  • stearoyl-CoA desaturase (delta-9-desaturase) (scd) antibody
  • stearoyl-CoA desaturase (delta-9-desaturase) (SCD) antibody
  • acyl-CoA delta-11 desaturase/conjugase (Desat1) antibody
  • acyl-CoA desaturase (Desat3) antibody
  • stearoyl-CoA desaturase (SCD) antibody
  • acyl-CoA desaturase (CIMG_08158) antibody
  • acyl-CoA desaturase (VIBHAR_06094) antibody
  • Acyl-CoA desaturase (acod) antibody
  • stearoyl-CoA desaturase 1 (LOC100346561) antibody
  • stearoyl-CoA desaturase (delta-9-desaturase) (Scd) antibody
  • stearoyl-Coenzyme A desaturase 1 (Scd1) antibody
  • stomatal cytokinesis defective / SCD1 protein (SCD1) (SCD1) antibody
  • AA589638 antibody
  • ab antibody
  • ACD antibody
  • AI265570 antibody
  • Desat2 antibody
  • F27J15.17 antibody
  • F27J15_17 antibody
  • FADS5 antibody
  • MSTP008 antibody
  • Scd antibody
  • Scd-1 antibody
  • SCD1 antibody
  • Scd2 antibody
  • SCDOS antibody

Protein level used designations for SCD

SCD1 , stearoyl-CoA desaturase 5 , stearoyl-CoA desaturase 1 , delta-9 desaturase , acyl-CoA delta-11 desaturase/conjugase , acyl CoA desaturase , pheromone gland-specific acyl-CoA desaturase , acyl-CoA desaturase , stearoyl-CoA desaturase , delta-9-desaturase , Acyl-CoA desaturase , stearoyl-CoA desaturase (delta-9-desaturase) , delta(9)-desaturase , fatty acid desaturase , predicted protein of HQ0998 , stearoyl-CoA desaturase opposite strand , stearoyl-coenzyme A desaturase , acyl-CoA desaturase 2 , delta(9)-desaturase 2 , delta-9 desaturase 2 , fatty acid desaturase 2 , stearoyl-CoA desaturase 2 , stearoyl-Coenzyme A desaturase 2 , acyl-CoA desaturase 1 , asebia , delta(9)-desaturase 1 , delta-9 desaturase 1 , fatty acid desaturase 1

386661 Danio rerio
395706 Gallus gallus
692567 Bombyx mori
692568 Bombyx mori
710155 Macaca mulatta
4560468 Coccidioides immitis RS
5556852 Vibrio campbellii ATCC BAA-1116
100126751 Papio anubis
100172656 Pongo abelii
100194951 Salmo salar
100346561 Oryctolagus cuniculus
447633 Xenopus laevis
450676 Pan troglodytes
486839 Canis lupus familiaris
613092 Xenopus (Silurana) tropicalis
6319 Homo sapiens
280924 Bos taurus
396670 Sus scrofa
443185 Ovis aries
83792 Rattus norvegicus
20249 Mus musculus
246074 Rattus norvegicus
841327 Arabidopsis thaliana
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