Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
SAMD9L encodes a sterile alpha motif domain-containing protein. Additionally we are shipping Sterile alpha Motif Domain Containing 9-Like Antibodies (27) and and many more products for this protein.
Showing 10 out of 11 products:
Progressive loss of mutated SAMD9 through the development of monosomy 7 (-7), deletions of 7q (7q-), and secondary somatic loss-of-function (nonsense and frameshift) mutations in SAMD9 rescued the growth-restricting effects of mutant SAMD9 proteins in bone marrow and was associated with increased length of survival.
SAMD9 mutation is associated with MIRAGE syndrome.
Gain-of-function SAMD9L mutations cause a syndrome of cytopenia, immunodeficiency, MDS (show PAFAH1B1 ELISA Kits), and neurological symptoms in two unrelated Caucasian families.
Missense Mutations in SAMD9L gene is Associated with Ataxia-Pancytopenia Syndrome.
Replication of the K1L(-)C7L(-) mutant vaccinia virus virus was enabled by multiple siRNAs to SAMD9 or WDR6 (show WDR6 ELISA Kits).
SAMD9 is down-regulated in non-small cell lung cancer. Knockdown of SAMD9 expression increased the invasion, migration and proliferation in H1299 cells in vitro and overexpression of SAMD9 suppressed proliferation and invasion in A549 cells.
When SAMD9 is stimulated due to failure of the viral antagonism during infection, the resulting antiviral granules exhibit properties different from those of the canonical stress granules.
The findings highlight a novel tumor-suppressive role of SAMD9L inactivation by somatic mutation and decreased expression in human HBV-related HCC (show FAM126A ELISA Kits)
Over-expression of SAMD9 is correlated with the metastasis of esophageal squamous cell carcinoma
M062 also binds and antagonizes cellular SAMD9 in human cells, suggesting that SAMD9 is a novel innate antiviral factor against poxviruses.
Haploinsufficiency of SAMD9L, an endosome fusion facilitator, causes myeloid malignancies in mice mimicking human diseases with monosomy 7.
Mouse Samd9l is not a functional paralogue of the human SAMD9.
mouse Samd9L revealed near-ubiquitous expression, with the highest level in the kidney, a major organ regulating calcium-phosphate homeostasis and the site of calcitonin (show CALCA ELISA Kits) hormonal action.
This gene encodes a sterile alpha motif domain-containing protein. The encoded protein localizes to the cytoplasm and may play a role in regulating cell proliferation and apoptosis. Mutations in this gene are the cause of normophosphatemic familial tumoral calcinosis. Alternate splicing results in multiple transcript variants that encode the same protein.
SAM domain-containing protein 9
, expressed in aggressive fibromatosis
, sterile alpha motif domain-containing protein 9
, SAM domain-containing protein 9-like
, sterile alpha motif domain-containing protein 9-like
, v-myc myelocytomatosis viral related oncogene, neuroblastoma derived