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The protein encoded by SOAT1 belongs to the acyltransferase family. Additionally we are shipping SOAT1 Antibodies (17) and SOAT1 Kits (2) and many more products for this protein.
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Higher Gleason grade was associated with lower LDLR (show LDLR Proteins) expression, lower SOAT1 and higher SQLE (show SQLE Proteins) expression. Besides high SQLE (show SQLE Proteins) expression, cancers that became lethal despite primary treatment were characterized by low LDLR (show LDLR Proteins) expression (odds ratio for highest versus lowest quintile, 0.37; 95% CI 0.18-0.76) and by low SOAT1 expression (odds ratio, 0.41; 95% CI 0.21-0.83).
Data indicate that mitotane confers adrenal-specific cytotoxicity and down-regulates steroidogenesis by inhibition of sterol-O-acyl-transferase 1 (SOAT1) leading to lipid-induced endoplasmic reticulum (ER) stress.
Suggest retinal pigment epithelium metabolism of 7-ketocholesterol occurs by esterification to fatty acids via cPLA2alpha (show PLA2G4A Proteins) and SOAT1 followed by selective efflux to HDL (show HSD11B1 Proteins).
These studies demonstrate that both SIAE and SOAT activities seem to be responsible for the enhanced level of Neu5,9Ac(2) in lymphoblasts, which is a hallmark in acute lymphoblastic leukemia
the polymorphism of rs1044925 in the ACAT-1 gene is mainly associated with female serum total cholesterol, LDL-C and ApoB levels in the Bai Ku Yao population
These findings suggest the potential involvement of MAPK (show MAPK1 Proteins) and STAT (show STAT1 Proteins) pathways in norcantharidin-induced apoptogenesis.
SF-1 (show NR5A1 Proteins)-dependent up-regulation of SOAT1 may be important for maintaining readily-releasable cholesterol reserves needed for active steroidogenesis and during episodes of recurrent stress.
Results show that signaling through ACAT/cholesterol esterification is a novel pathway for the CCK2R (show CCKBR Proteins) that contributes to tumor cell proliferation and invasion.
polymorphism of the gene encoding acyl-coenzyme A (show SOAT2 Proteins): cholesterol acyltransferase 1 (SOAT1) is involved in the regulation of beta-amyloid peptide (show APP Proteins) generation, is associated with low brain amyloid load and with low cerebrospinal fluid levels of cholesterol
ACAT-1 transcripts predominate in human liver and ACAT-2 transcripts predominate in human duodenum and support the notion that ACAT-2 has an important regulatory role in liver and intestine.
a potential regulatory relationship between the sterol O-acetyltransferase 1 gene and Hoxc13 gene
Soat1 is a quantitative trait loci gene contributing to hyperlipidemia.
soat1 had an important role in normal hair formation
ACAT1 activity plays a central role in the proper trafficking of cholesterol and in cholesterol-sensing in the macrophage.
The protein encoded by this gene belongs to the acyltransferase family. It is located in the endoplasmic reticulum, and catalyzes the formation of fatty acid-cholesterol esters. This gene has been implicated in the formation of beta-amyloid and atherosclerotic plaques by controlling the equilibrium between free cholesterol and cytoplasmic cholesteryl esters. Alternatively spliced transcript variants have been found for this gene.
sterol O-acyltransferase (acyl-Coenzyme A: cholesterol acyltransferase) 1
, sterol O-acyltransferase 1
, sterol O-acyltransferase 1-like
, sterol O-acyltransferase
, acyl-coenzyme A:cholesterol acyltransferase 1
, acyl coenzyme A:cholesterol acyltransferase 1
, adrenocortical lipid depletion
, cholesterol acyltransferase 1
, acyltransferase wax synthase
, Acyl-coenzyme A:cholesterol acyltransferase 1
, Cholesterol acyltransferase 1