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Scrapie-responsive gene 1 is associated with neurodegenerative changes observed in transmissible spongiform encephalopathies. Additionally we are shipping SCRG1 Kits (2) and and many more products for this protein.
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Scrg1 is associated with the secretory pathway of neuronal cells.
Taken together, our results indicate that Scrg1 is associated with neurodegenerative processes in TSE, but is not directly linked to dysregulation of prion protein (show PRNP Proteins).
Aomatsu et al. identified a novel SCRG1/BST1 (CD157 (show BST1 Proteins)) ligand-receptor combination that maintains human mesenchymal stem cells expressions of stem cell markers Oct-4 (show POU5F1 Proteins) and CD271 (show NGFR Proteins) (LNGFR (show NGFR Proteins)), as well as self-renewal, migration, and osteogenic differentiation potentials during ex vivo expansion.
Scrapie-responsive gene 1 is associated with neurodegenerative changes observed in transmissible spongiform encephalopathies. It may play a role in host response to prion-associated infections. The scrapie responsive protein 1 may be partly included in the membrane or secreted by the cells due to its hydrophobic N-terminus.
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