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Streptolysin O Proteins

(Streptolysin O (SLO))
Sulfhydryl-activated toxin that causes cytolysis by forming pores in cholesterol containing host membranes. After binding to target membranes, the protein undergoes a major conformation change, leading to its insertion in the host membrane and formation of an oligomeric pore complex. Cholesterol may be required for binding to host membranes, membrane insertion and pore formation. Can be reversibly inactivated by oxidation (By similarity).
Streptolysin O Protein (SLO) Streptolysin O Protein (SLO) Streptolysin O Protein (SLO) (ABIN2452205)

SLO Origin: Streptococcus pyogenes Host: Escherichia coli (E. coli) Recombinant > 98 % by SDS-PAGE ELISA, WB, SDS Active

Streptolysin O Protein (SLO) (ABIN2017554)

SLO Origin: Streptococcus pyogenes Host: Escherichia coli (E. coli) Recombinant

Streptolysin O Protein (SLO) (ABIN1543636)

SLO Origin: Human Host: Escherichia coli (E. coli) Recombinant Pure ELISA, WB

Streptolysin O Proteins by Origin

Find Streptolysin O Proteins for a variety of species such as anti-Streptococcus pyogenes Streptolysin O, anti-Human Streptolysin O. The species listed below are among those available. Click on a link to go to the corresponding products.

Streptolysin O Proteins by Source

Here you will find Streptolysin O Proteins proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

Streptolysin O Proteins by Protein Type

Here you can find Streptolysin O Proteins proteins categorized by available protein types. Additional protein types can be located using our search function.

Streptolysin O Proteins by Application

Find Streptolysin O Proteins validated for a specific application such as ELISA, WB, SDS. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Streptolysin O Proteins by Biological Activity

Find Streptolysin O Proteins with a specific Biological Activity. The Biological Activity listed below are among those available. Click on a link to go to the corresponding products.

Popular Streptolysin O Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Streptococcus pyogenes
Source Escherichia coli (E. coli)
Validations
  • (3)
  • (2)
Cat. No. ABIN2452205
Quantity 20 μg
Datasheet Datasheet
Reactivity Streptococcus pyogenes
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN2017554
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN1543636
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN1543635
Quantity 100 μg
Datasheet Datasheet
Reactivity Streptococcus pyogenes
Source Bacteria
Validations
Cat. No. ABIN1045131
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our Streptolysin O Proteins

Maeda, Ide, Koike, Uchiyama, Kinoshita: "GPHR is a novel anion channel critical for acidification and functions of the Golgi apparatus." in: Nature cell biology, Vol. 10, Issue 10, pp. 1135-45, (2008) (PubMed).

Walev, Bhakdi, Hofmann, Djonder, Valeva, Aktories, Bhakdi: "Delivery of proteins into living cells by reversible membrane permeabilization with streptolysin-O." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 98, Issue 6, pp. 3185-90, (2001) (PubMed).

Palmer: "The family of thiol-activated, cholesterol-binding cytolysins." in: Toxicon : official journal of the International Society on Toxinology, Vol. 39, Issue 11, pp. 1681-9, (2001) (PubMed).

Aliases for Streptolysin O Proteins

streptolysin O (slo) Proteins
streptolysin O (M6_Spy0188) Proteins
Streptolysin O (slo) Proteins
Thiol-activated cytolysin (slo) Proteins
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